[Biopython] topology of transmembrane proteins in BioPython
Afonso Duarte
aduarte at itqb.unl.pt
Tue Nov 20 16:50:26 UTC 2012
>> Or would a simple linear protein diagram work, with one or more
>> blocks/shapes along the length (from N terminus to C terminus), as
>> often used for showing protein domains? That should be possible using
>> Biopython's GenomeDiagram (normally used for showing genes or regions
>> on a genome, but you could equally show domains or regions on a
>> protein).
>>That would give something a bit like this:
>>http://www0.cs.ucl.ac.uk/staff/T.Nugent/images/BACS2_NATPH_consensus.png
Actually this one I'm also interested in and so far works ok, but does not
produce the topology as in my previous message .
Thank
Afonso
-----Mensagem original-----
De: Peter Cock [mailto:p.j.a.cock at googlemail.com]
Enviada: terça-feira, 20 de Novembro de 2012 15:28
Para: Fields, Christopher J
Cc: Afonso Duarte; <biopython at lists.open-bio.org>
Assunto: Re: [Biopython] topology of transmembrane proteins in BioPython
On Tue, Nov 20, 2012 at 3:23 PM, Fields, Christopher J
<cjfields at illinois.edu> wrote:
> There was some code submitted to BioPerl a while back that does this, it's
now in Lincoln's Bio-Graphics module (which uses libgd2):
>
>
> https://github.com/GMOD/Bio-Graphics/blob/master/lib/Bio/Graphics/Draw
> Transmembrane.pm
>
> I recall testing it and it worked well, but it's been quite a while. It
seemed pretty straightforward if someone wanted to try porting it.
>
> chris
That produces images like this does it?
http://www0.cs.ucl.ac.uk/staff/T.Nugent/images/CLN3_Consensus_Labelled.png
>From here:
http://www0.cs.ucl.ac.uk/staff/T.Nugent/code.html
> On Nov 20, 2012, at 9:12 AM, Peter Cock <p.j.a.cock at googlemail.com>
>>
>> Do you want to draw a protein threading through a membrane?
See above, I was meaning something like this:
http://www0.cs.ucl.ac.uk/staff/T.Nugent/images/CLN3_Consensus_Labelled.png
>> Or would a simple linear protein diagram work, with one or more
>> blocks/shapes along the length (from N terminus to C terminus), as
>> often used for showing protein domains? That should be possible using
>> Biopython's GenomeDiagram (normally used for showing genes or regions
>> on a genome, but you could equally show domains or regions on a
>> protein).
That would give something a bit like this:
http://www0.cs.ucl.ac.uk/staff/T.Nugent/images/BACS2_NATPH_consensus.png
Again, from here:
http://www0.cs.ucl.ac.uk/staff/T.Nugent/code.html
Peter
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