[Biopython-dev] [Bug 2366] Ambiguous nucleotides in (Reverse)complement functions in Bio.Seq

[bugzilla-daemon at portal.open-bio.org]

http://bugzilla.open-bio.org/show_bug.cgi?id=2366





------- Comment #7 from biopython-bugzilla at maubp.freeserve.co.uk  2007-10-17 04:46 EST -------
Fixed, I think.

I had some RNA/DNA with the U and T the wrong way round... and when I recently
tweaked the alphabet detection in Bio/Seq.py this had an impact.

The root issue is that we don't check the Alphabet's letters agree with the
sequence when creating a Seq object (where the Alphabet supplied has an
explicit list of letters).  That would have caught the error in the test suite
much earlier.  Maybe I should file an enhancement bug on this issue.


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