[Biopython] align single sequence to MSA

Frank Kauff fkauff at biologie.uni-kl.de
Mon Sep 26 14:54:15 UTC 2011


Hi,

Yes, clustal can do this easily. If I remember correctly the command 
line should be something like

clustalw -sequences -profile1=mas_file.fas -profile2=new_sequences.fas

Frank


On 09/12/2011 03:00 AM, Nasos Dousis wrote:
> Hello,
>
> First, thank you to everyone who has contributed to the BioPython
> codebase and to the mailing list.
>
> I have a FASTA sequence, and I'd like to find the optimal alignment of
> that sequence to an MSA.  I don't want to alter the MSA-- I just want
> to map the single sequence onto the MSA.  Is there a simple way to do
> this by ClustalW or MUSCLE?
>
> Thanks,
> Nasos
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