[Bioperl-l] amino acid index

Heikki Lehvaslaiho heikki@ebi.ac.uk
Thu, 04 Jul 2002 13:37:39 +0100


Navdeep,


How about Bio::ProteinProperty::AAIndex?


First you better think how to represent the index information. You need a 
class for that, You could put that in
Bio::Tools::AAIndex::Index  or  Bio::ProteinProperty::AAindex::Index. 
Bio::ProteinProperty::AAIndex::Indexer could know about a Index and a 
protein sequence (Bio::PrimarySeqI object with alphabet('protein')).

Then you need to think how to get a index. 
Bio::ProteinProperty::AAIndex::IO.pm could read and write the flat file 
format with the help of Bio::ProteinProperty::AAIndex::IO::aaindex.pm 
module, - or if you think there ever will be only flat fie format the Index 
class could do the IO.

Next you need to get  the indexes. If it comes over the web from the AAIndex 
   database, write a module Bio::DB::AAIndex. There are many other options 
if plan to support local databases.

	-Heikki



Navdeep Jaitly wrote:
> I was planning to write some for my use, if there wasn't an 
> implementation already. I could make it available / submit changes to 
> the bioperl cvs.
> I think Bio::Tools::AAIndex would be a good place to provide AAIndex 
> access. Comments/suggestions ?
> Deep
> 
> 
> 
>> From: Heikki Lehvaslaiho <heikki@ebi.ac.uk>
>> To: Navdeep Jaitly <ndjaitly@hotmail.com>
>> CC: bioperl-l@bioperl.org
>> Subject: Re: [Bioperl-l] amino acid index
>> Date: Thu, 04 Jul 2002 09:16:12 +0100
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>>
>> There isn't. Are planning to write something?
>>
>>     -Heikki
>>
>>
>>
>> Navdeep Jaitly wrote:
>>
>>> Hi!
>>> Is there any on-going work that would allow users to calculate 
>>> AAIndex values for a peptide by specifying an accession number for an 
>>> AAIndex ?
>>> Cheers!
>>> Deep
>>>
>>>
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>>
>>
>> -- 
>> ______ _/      _/_____________________________________________________
>>       _/      _/                      http://www.ebi.ac.uk/mutations/
>>      _/  _/  _/  Heikki Lehvaslaiho          heikki@ebi.ac.uk
>>     _/_/_/_/_/  EMBL Outstation, European Bioinformatics Institute
>>    _/  _/  _/  Wellcome Trust Genome Campus, Hinxton
>>   _/  _/  _/  Cambs. CB10 1SD, United Kingdom
>>      _/      Phone: +44 (0)1223 494 644   FAX: +44 (0)1223 494 468
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-- 
______ _/      _/_____________________________________________________
       _/      _/                      http://www.ebi.ac.uk/mutations/
      _/  _/  _/  Heikki Lehvaslaiho          heikki@ebi.ac.uk
     _/_/_/_/_/  EMBL Outstation, European Bioinformatics Institute
    _/  _/  _/  Wellcome Trust Genome Campus, Hinxton
   _/  _/  _/  Cambs. CB10 1SD, United Kingdom
      _/      Phone: +44 (0)1223 494 644   FAX: +44 (0)1223 494 468
___ _/_/_/_/_/________________________________________________________