[EMBOSS] needle question!
    Karen Hayden 
    kehayden at gmail.com
       
    Thu Feb  8 22:17:52 UTC 2007
    
    
  
Hello,
 I am currently using needle to generate an alignment between two
sequences which contain non-informative bases (ie, identified low
quality bases (phred scores) and have been changed to  "N").
Presently,  these bases are penalized as any other non-matching
character.  Is there any way to change needle to "overlook" these
bases when generating the best scoring alignment (or, do I need to
write my own version of needle?)
Thank you in advance for any advise you can offer!
Best regards,
Karen
    
    
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