[Dynamite] Is this working now then?

Ian Holmes ihh@fruitfly.org
Mon, 6 Mar 2000 15:04:41 -0800 (PST)


On Tue, 7 Mar 2000, Ewan Birney wrote:

> 
> 
> On Mon, 6 Mar 2000, Ian Holmes wrote:
> 
> > On Mon, 6 Mar 2000, Ewan Birney wrote:
> > 
> > > > > (NB I think all alignment algorithms should be global at the minute. Doing
> > > > > local alignment is effectively an optimisation step, equivalent to saying
> > > > > that some cells are zero throughout the matrix)
> > > > 
> > > > No!  I'm v.against implementing everything as global and hacking in
> > > > local alignments later.  Something like that needs to work from the start.
> > > 
> > > I am with Guy here actually. We will need global/local switches to be
> > > nicely placed in the models.
> > 
> > I feel like I am swimming upstream here Ewan. This is not the first time
> > we've discussed global/local models, only the first time on this list...
> > have you changed your mind recently?
> 
> Bugger. I am now caught agree with *both* you and Guy. I have to think 
> about this a bit more.
> 

Yes please do -- I don't think what I proposed is hacky. But it also has
to be comprehensible. So feedback == good.