[BioRuby] FFI to Smith/Waterman and Needleman/Wunsh C-extension

Michael Barton mail at michaelbarton.me.uk
Mon Feb 21 17:06:07 UTC 2011


Hi,

Does anyone know of a ruby library for doing local and global sequence
alignment? I'm interested in performing these kind of alignments in ruby but
would prefer not to call command line tools such as EMBOSS. I think it could be
useful to have a ruby gem which installs a C-extension for allowing for
reasonably fast alignment. A cursory look on pubmed turned these links for
C libraries.

http://www.ncbi.nlm.nih.gov/pubmed/18959793
http://www.ncbi.nlm.nih.gov/books/NBK7151/

Mike


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