[Biopython] Looking for Python DNA melting temp calculator

Ogan ABAAN oda.gumail at gmail.com
Tue Apr 19 13:15:31 EDT 2011


I have code I generated a few year back that I use on a daily bases for 
Tm calculations. It is based on NN with all the monovalent ion, Mg+2, 
dNTP, DNA and even DMSO concentration corrections. I included all the 
references in the function it self if anyone is interested.

I don't know what the proper way to post the function, so please advice. 
I will be happy to share it.

Ogan


On 4/17/11 12:54 PM, Uri Laserson wrote:
> For simple oligo Tm calculations, I use this code which I inherited from
> someone (based on the NN model):
>
> http://goo.gl/buoQc
>
> A more fully-fledged package is available as part of Brad Chapman's code
> from Codon Devices:
>
> http://goo.gl/fPdAN
>
> I was under the impression that Primer3 uses a less accurate model for Tm
> calculations.
>
> ...................................................................................
> Uri Laserson
> Graduate Student, Biomedical Engineering
> Harvard-MIT Division of Health Sciences and Technology
> M +1 917 742 8019
> laserson at mit.edu
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