[BioPython] Lowess function for nonparametric regression
Michiel Jan Laurens de Hoon
mdehoon at ims.u-tokyo.ac.jp
Fri Apr 30 02:58:29 EDT 2004
Dear Biopythoneers,
Recently I wrote a pure Python implementation of the Lowess function for
nonparametric regression. For an example, see
http://bonsai.ims.u-tokyo.ac.jp/~mdehoon/lowess.png
the red line is a nonparametric regression curve fitted to the scatterplot. The
value on the x-axis is the mean of replicated gene expression measurements; the
y-axis is the associated measurement error. Such plots are used to find out how
large the measurement error typically is for a given magnitude of a measured
gene expression level.
If this function is useful for other computational biologists, I can submit it
to Biopython. In that case, which module would this fall under? Or can I just
make a Lowess.py under Bio? The code is very short, about 25 lines of Python for
the actual function.
--Michiel
--
Michiel de Hoon, Assistant Professor
University of Tokyo, Institute of Medical Science
Human Genome Center
4-6-1 Shirokane-dai, Minato-ku
Tokyo 108-8639
Japan
http://bonsai.ims.u-tokyo.ac.jp/~mdehoon
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