[BioPython] problem with Blast/NCBIWWW parser ?
Catherine Letondal
letondal@pasteur.fr
Sat, 25 May 2002 19:21:49 +0200
--M9NhX3UHpAaciwkO
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Hi,
I have dowloaded the last version of
biopython/Bio/Blast/NCBIWWW.py file from CVS, and
I still get an error when I run it on a Blast report just obtained from
the NCBI:
Traceback (most recent call last):
File "exercises/blast_swissprot_parse.py", line 6, in ?
record = blast_parser.parse(blast_results)
File "/usr/local/lib/python2.2/site-packages/Bio/Blast/NCBIWWW.py",
line 47, i
n parse
self._scanner.feed(handle, self._consumer)
File "/usr/local/lib/python2.2/site-packages/Bio/Blast/NCBIWWW.py",
line 99, i
n feed
self._scan_rounds(uhandle, consumer)
File "/usr/local/lib/python2.2/site-packages/Bio/Blast/NCBIWWW.py",
line 203,
read_and_call(uhandle, consumer.score, start=' Score')
File "/usr/local/lib/python2.2/site-packages/Bio/ParserSupport.py",
line 331,
in read_and_call
raise SyntaxError, errmsg
SyntaxError: Line does not start with ' Score':
I attach the remote blast result.
Could someone help?
Thanks in advance,
--
Catherine Letondal -- Pasteur Institute Computing Center
--M9NhX3UHpAaciwkO
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<IMG SRC="images/head_results.gif" ALT="Header of the page" BORDER="0"NAME="BlastHeaderGif" WIDTH="600" HEIGHT="45" ALIGN="middle">
<form action="Blast.cgi" enctype="application/x-www-form-urlencoded" method="POST"><input name="ALIGNMENTS" type="hidden" value="50"><input name="AUTO_FORMAT" type="hidden" value="on"><input name="CLIENT" type="hidden" value="web"><input name="DESCRIPTIONS" type="hidden" value="100"><input name="EXPECT" type="hidden" value="1"><input name="HITLIST_SIZE" type="hidden" value="100"><input name="I_THRESH" type="hidden" value="0.001"><input name="LAYOUT" type="hidden" value="OneWindow"><input name="NCBI_GI" type="hidden" value="checked"><input name="PAGE" type="hidden" value="Proteins"><input name="RID" type="hidden" value="1022346244-01943-22277"><input name="RTOE" type="hidden" value="4"><input name="SHOW_OVERVIEW" type="hidden" value="checked"><input name="STEP_NUMBER" type="hidden" value="1"><input name="defline" type="hidden" value="Click on the image below for detailed CD-Search results"><input name="CMD" type="hidden" value="Get"></form>
<form action="Blast.cgi" enctype="application/x-www-form-urlencoded" method="POST" TARGET=""><input name="ALIGNMENTS" type="hidden" value="50"><input name="AUTO_FORMAT" type="hidden" value="on"><input name="CLIENT" type="hidden" value="web"><input name="DESCRIPTIONS" type="hidden" value="100"><input name="EXPECT" type="hidden" value="1"><input name="HITLIST_SIZE" type="hidden" value="100"><input name="I_THRESH" type="hidden" value="0.001"><input name="LAYOUT" type="hidden" value="OneWindow"><input name="NCBI_GI" type="hidden" value="checked"><input name="PAGE" type="hidden" value="Proteins"><input name="RID" type="hidden" value="1022346244-01943-22277"><input name="RTOE" type="hidden" value="4"><input name="SHOW_OVERVIEW" type="hidden" value="checked"><input name="STEP_NUMBER" type="hidden" value="1"><input name="CMD" type="hidden" value="Put">
<p><!--
QBlastInfoBegin
Status=READY
QBlastInfoEnd
--><p><TITLE> RID=1022346244-01943-22277, CERU_HUMAN STANDARD; PRT; 1065 AA., 1065 bases, 78C9415D checksum. </TITLE>
<b>BLASTP 2.2.3 [Apr-24-2002]</b>
<pre>
<b><a href="http://www.ncbi.nlm.nih.gov/htbin-
post/Entrez/query?uid=9254694&form=6&db=m&Dopt=r">Reference</a>:</b>
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
<p>
RID: 1022346244-01943-22277
<p>
<b>Query=</b> CERU_HUMAN STANDARD; PRT; 1065 AA., 1065
bases, 78C9415D checksum.
(1065 letters)
<p>
<b>Database:</b> Non-redundant SwissProt sequences
109,592 sequences; 40,014,366 total letters
<p> <p>If you have any problems or questions with the results of this search <br>please refer to the <b><a href=http://www.ncbi.nlm.nih.gov/blast/blast_FAQs.html>BLAST FAQs</a></b><br><p>
<a href="Blast.cgi?CMD=Get&RID=1022346244-01943-22277&FORMAT_OBJECT=TaxBlast" TARGET="Taxonomy BLAST Results for 1022346244-01943-22277">Taxonomy reports</a>
<BR>
<PRE>
Score E
Sequences producing significant alignments: (bits) Value
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=00116117&dopt=GenPept" >sp|P00450|CERU_HUMAN</a> CERULOPLASMIN PRECURSOR (FERROXIDASE) <a href = #116117>2235</a> 0.0
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02493322&dopt=GenPept" >sp|Q61147|CERU_MOUSE</a> CERULOPLASMIN PRECURSOR (FERROXIDASE) <a href = #2493322>1868</a> 0.0
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02506226&dopt=GenPept" >sp|P13635|CERU_RAT</a> CERULOPLASMIN PRECURSOR (FERROXIDASE) <a href = #2506226>1851</a> 0.0
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=00119767&dopt=GenPept" >sp|P00451|FA8_HUMAN</a> Coagulation factor VIII precursor (Proc... <a href = #119767>426</a> e-119
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=00544272&dopt=GenPept" >sp|Q06194|FA8_MOUSE</a> Coagulation factor VIII precursor (Proc... <a href = #544272>417</a> e-116
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02506228&dopt=GenPept" >sp|P12263|FA8_PIG</a> Coagulation factor VIII precursor (Procoa... <a href = #2506228>416</a> e-115
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02493324&dopt=GenPept" >sp|Q28107|FA5_BOVIN</a> Coagulation factor V precursor (Activat... <a href = #2493324>405</a> e-112
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=18202922&dopt=GenPept" >sp|Q9GLP1|FA5_PIG</a> Coagulation factor V precursor (Activated... <a href = #18202922>402</a> e-111
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=00462045&dopt=GenPept" >sp|P12259|FA5_HUMAN</a> Coagulation factor V precursor (Activat... <a href = #462045>399</a> e-110
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=01351670&dopt=GenPept" >sp|Q09920|YAK8_SCHPO</a> Putative multicopper oxidase C1F7.08 p... <a href = #1351670> 55</a> 9e-07
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02833227&dopt=GenPept" >sp|Q12541|LAC1_AGABI</a> LACCASE I PRECURSOR (BENZENEDIOL:OXYGE... <a href = #2833227> 46</a> 3e-04
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02833228&dopt=GenPept" >sp|Q12542|LAC2_AGABI</a> LACCASE II PRECURSOR (BENZENEDIOL:OXYG... <a href = #2833228> 46</a> 3e-04
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02493321&dopt=GenPept" >sp|Q40588|ASO_TOBAC</a> L-ASCORBATE OXIDASE PRECURSOR (ASCORBAS... <a href = #2493321> 45</a> 0.001
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=00114270&dopt=GenPept" >sp|P14133|ASO_CUCSA</a> L-ASCORBATE OXIDASE PRECURSOR (ASCORBAS... <a href = #114270> 44</a> 0.002
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=00543859&dopt=GenPept" >sp|P37064|ASO_CUCPM</a> L-ASCORBATE OXIDASE (ASCORBASE) (ASO) <a href = #543859> 43</a> 0.003
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02827764&dopt=GenPept" >sp|P24792|ASO_CUCMA</a> L-ASCORBATE OXIDASE PRECURSOR (ASCORBASE) <a href = #2827764> 42</a> 0.005
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02833234&dopt=GenPept" >sp|Q12719|LAC4_TRAVE</a> LACCASE 4 PRECURSOR (BENZENEDIOL:OXYGE... <a href = #2833234> 42</a> 0.008
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02842755&dopt=GenPept" >sp|Q99055|LAC4_TRAVI</a> LACCASE 4 PRECURSOR (BENZENEDIOL:OXYGE... <a href = #2842755> 42</a> 0.008
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02833229&dopt=GenPept" >sp|Q12570|LAC1_BOTCI</a> LACCASE (BENZENEDIOL:OXYGEN OXIDOREDUC... <a href = #2833229> 40</a> 0.017
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02829462&dopt=GenPept" >sp|P56193|LAC1_THACU</a> LACCASE 1 PRECURSOR (BENZENEDIOL:OXYGE... <a href = #2829462> 40</a> 0.023
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02833189&dopt=GenPept" >sp|Q02075|LAC2_THACU</a> LACCASE 2 PRECURSOR (BENZENEDIOL:OXYGE... <a href = #2833189> 40</a> 0.023
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=00400156&dopt=GenPept" >sp|Q01679|LAC1_PHLRA</a> Laccase precursor (Benzenediol:oxygen ... <a href = #400156> 39</a> 0.039
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02833199&dopt=GenPept" >sp|Q03966|LAC1_CRYPA</a> LACCASE PRECURSOR (BENZENEDIOL:OXYGEN ... <a href = #2833199> 39</a> 0.050
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02493323&dopt=GenPept" >sp|P78591|FET3_CANAL</a> IRON TRANSPORT MULTICOPPER OXIDASE PRE... <a href = #2493323> 39</a> 0.050
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=18281739&dopt=GenPept" >sp|Q99056|LAC5_TRAVI</a> Laccase 5 precursor (Benzenediol:oxyge... <a href = #18281739> 39</a> 0.050
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02842752&dopt=GenPept" >sp|Q99044|LAC1_TRAVI</a> LACCASE 1 PRECURSOR (BENZENEDIOL:OXYGE... <a href = #2842752> 38</a> 0.086
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=01730082&dopt=GenPept" >sp|Q02497|LAC1_CORHI</a> Laccase precursor (Benzenediol:oxygen ... <a href = #1730082> 38</a> 0.086
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02842753&dopt=GenPept" >sp|Q99046|LAC2_TRAVI</a> LACCASE 2 PRECURSOR (BENZENEDIOL:OXYGE... <a href = #2842753> 38</a> 0.11
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=01175947&dopt=GenPept" >sp|P43561|FET5_YEAST</a> Iron transport multicopper oxidase FET... <a href = #1175947> 38</a> 0.11
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02833233&dopt=GenPept" >sp|Q12718|LAC2_TRAVE</a> Laccase 2 precursor (Benzenediol:oxyge... <a href = #2833233> 38</a> 0.11
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02833190&dopt=GenPept" >sp|Q02079|LAC3_THACU</a> LACCASE 3 PRECURSOR (BENZENEDIOL:OXYGE... <a href = #2833190> 37</a> 0.15
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02833237&dopt=GenPept" >sp|Q12739|LAC2_PLEOS</a> LACCASE 2 PRECURSOR (BENZENEDIOL:OXYGE... <a href = #2833237> 37</a> 0.15
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02833232&dopt=GenPept" >sp|Q12717|LAC5_TRAVE</a> LACCASE 5 PRECURSOR (BENZENEDIOL:OXYGE... <a href = #2833232> 37</a> 0.15
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02833235&dopt=GenPept" >sp|Q12729|LAC1_PLEOS</a> LACCASE 1 PRECURSOR (BENZENEDIOL:OXYGE... <a href = #2833235> 37</a> 0.19
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02833200&dopt=GenPept" >sp|Q04399|YD56_YEAST</a> PUTATIVE MULTICOPPER OXIDASE YDR506C <a href = #2833200> 37</a> 0.19
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02828219&dopt=GenPept" >sp|P38993|FET3_YEAST</a> Iron transport multicopper oxidase FET... <a href = #2828219> 37</a> 0.25
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02827765&dopt=GenPept" >sp|P25006|NIR_ACHCY</a> COPPER-CONTAINING NITRITE REDUCTASE PRE... <a href = #2827765> 36</a> 0.43
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=13632794&dopt=GenPept" >sp|Q47452|PCOA_ECOLI</a> Copper resistance protein A precursor <a href = #13632794> 36</a> 0.43
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=20137839&dopt=GenPept" >sp|Q8ZRS2|CUEO_SALTY</a> Blue copper oxidase cueO precursor (Co... <a href = #20137839> 35</a> 0.56
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=20137822&dopt=GenPept" >sp|Q8Z9E1|CUEO_SALTI</a> Blue copper oxidase cueO precursor (Co... <a href = #20137822> 35</a> 0.56
<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=00116921&dopt=GenPept" >sp|P12374|COPA_PSESM</a> Copper resistance protein A precursor <a href = #116921> 35</a> 0.73
</PRE>
<CENTER><b><FONT color="green">Alignments</FONT></b></CENTER>
<PRE>
><a name = 116117></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=00116117&dopt=GenPept" >sp|P00450|CERU_HUMAN</a> CERULOPLASMIN PRECURSOR (FERROXIDASE)
Length = 1065
Score = 2235 bits (5792), Expect = 0.0
Identities = 1065/1065 (100%), Positives = 1065/1065 (100%)
Query: 1 MKILILGIFLFLCSTPAWAKEKHYYIGIIETTWDYASDHGEKKLISVDTEHSNIYLQNGP 60
MKILILGIFLFLCSTPAWAKEKHYYIGIIETTWDYASDHGEKKLISVDTEHSNIYLQNGP
Sbjct: 1 MKILILGIFLFLCSTPAWAKEKHYYIGIIETTWDYASDHGEKKLISVDTEHSNIYLQNGP 60
Query: 61 DRIGRLYKKALYLQYTDETFRTTIEKPVWLGFLGPIIKAETGDKVYVHLKNLASRPYTFH 120
DRIGRLYKKALYLQYTDETFRTTIEKPVWLGFLGPIIKAETGDKVYVHLKNLASRPYTFH
Sbjct: 61 DRIGRLYKKALYLQYTDETFRTTIEKPVWLGFLGPIIKAETGDKVYVHLKNLASRPYTFH 120
Query: 121 SHGITYYKEHEGAIYPDNTTDFQRADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYH 180
SHGITYYKEHEGAIYPDNTTDFQRADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYH
Sbjct: 121 SHGITYYKEHEGAIYPDNTTDFQRADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYH 180
Query: 181 SHIDAPKDIASGLIGPLIICKKDSLDKEKEKHIDREFVVMFSVVDENFSWYLEDNIKTYC 240
SHIDAPKDIASGLIGPLIICKKDSLDKEKEKHIDREFVVMFSVVDENFSWYLEDNIKTYC
Sbjct: 181 SHIDAPKDIASGLIGPLIICKKDSLDKEKEKHIDREFVVMFSVVDENFSWYLEDNIKTYC 240
Query: 241 SEPEKVDKDNEDFQESNRMYSVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFH 300
SEPEKVDKDNEDFQESNRMYSVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFH
Sbjct: 241 SEPEKVDKDNEDFQESNRMYSVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFH 300
Query: 301 GQALTNKNYRIDTINLFPATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQVQECNKS 360
GQALTNKNYRIDTINLFPATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQVQECNKS
Sbjct: 301 GQALTNKNYRIDTINLFPATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQVQECNKS 360
Query: 361 SSKDNIRGKHVRHYYIAAEEIIWNYAPSGIDIFTKENLTAPGSDSAVFFEQGTTRIGGSY 420
SSKDNIRGKHVRHYYIAAEEIIWNYAPSGIDIFTKENLTAPGSDSAVFFEQGTTRIGGSY
Sbjct: 361 SSKDNIRGKHVRHYYIAAEEIIWNYAPSGIDIFTKENLTAPGSDSAVFFEQGTTRIGGSY 420
Query: 421 KKLVYREYTDASFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGV 480
KKLVYREYTDASFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGV
Sbjct: 421 KKLVYREYTDASFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGV 480
Query: 481 RFNKNNEGTYYSPNYNPQSRSVPPSASHVAPTETFTYEWTVPKEVGPTNADPVCLAKMYY 540
RFNKNNEGTYYSPNYNPQSRSVPPSASHVAPTETFTYEWTVPKEVGPTNADPVCLAKMYY
Sbjct: 481 RFNKNNEGTYYSPNYNPQSRSVPPSASHVAPTETFTYEWTVPKEVGPTNADPVCLAKMYY 540
Query: 541 SAVDPTKDIFTGLIGPMKICKKGSLHANGRQKDVDKEFYLFPTVFDENESLLLEDNIRMF 600
SAVDPTKDIFTGLIGPMKICKKGSLHANGRQKDVDKEFYLFPTVFDENESLLLEDNIRMF
Sbjct: 541 SAVDPTKDIFTGLIGPMKICKKGSLHANGRQKDVDKEFYLFPTVFDENESLLLEDNIRMF 600
Query: 601 TTAPDQVDKEDEDFQESNKMHSMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGIYF 660
TTAPDQVDKEDEDFQESNKMHSMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGIYF
Sbjct: 601 TTAPDQVDKEDEDFQESNKMHSMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGIYF 660
Query: 661 SGNTYLWRGERRDTANLFPQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTVNQCRR 720
SGNTYLWRGERRDTANLFPQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTVNQCRR
Sbjct: 661 SGNTYLWRGERRDTANLFPQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTVNQCRR 720
Query: 721 QSEDSTFYLGERTYYIAAVEVEWDYSPQREWEKELHHLQEQNVSNAFLDKGEFYIGSKYK 780
QSEDSTFYLGERTYYIAAVEVEWDYSPQREWEKELHHLQEQNVSNAFLDKGEFYIGSKYK
Sbjct: 721 QSEDSTFYLGERTYYIAAVEVEWDYSPQREWEKELHHLQEQNVSNAFLDKGEFYIGSKYK 780
Query: 781 KVVYRQYTDSTFRVPVERKAEEEHLGILGPQLHADVGDKVKIIFKNMATRPYSIHAHGVQ 840
KVVYRQYTDSTFRVPVERKAEEEHLGILGPQLHADVGDKVKIIFKNMATRPYSIHAHGVQ
Sbjct: 781 KVVYRQYTDSTFRVPVERKAEEEHLGILGPQLHADVGDKVKIIFKNMATRPYSIHAHGVQ 840
Query: 841 TESSTVTPTLPGETLTYVWKIPERSGAGTEDSACIPWAYYSTVDQVKDLYSGLIGPLIVC 900
TESSTVTPTLPGETLTYVWKIPERSGAGTEDSACIPWAYYSTVDQVKDLYSGLIGPLIVC
Sbjct: 841 TESSTVTPTLPGETLTYVWKIPERSGAGTEDSACIPWAYYSTVDQVKDLYSGLIGPLIVC 900
Query: 901 RRPYLKVFNPRRKLEFALLFLVFDENESWYLDDNIKTYSDHPEKVNKDDEEFIESNKMHA 960
RRPYLKVFNPRRKLEFALLFLVFDENESWYLDDNIKTYSDHPEKVNKDDEEFIESNKMHA
Sbjct: 901 RRPYLKVFNPRRKLEFALLFLVFDENESWYLDDNIKTYSDHPEKVNKDDEEFIESNKMHA 960
Query: 961 INGRMFGNLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRGVYSSDVFDIFP 1020
INGRMFGNLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRGVYSSDVFDIFP
Sbjct: 961 INGRMFGNLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRGVYSSDVFDIFP 1020
Query: 1021 GTYQTLEMFPRTPGIWLLHCHVTDHIHAGMETTYTVLQNEDTKSG 1065
GTYQTLEMFPRTPGIWLLHCHVTDHIHAGMETTYTVLQNEDTKSG
Sbjct: 1021 GTYQTLEMFPRTPGIWLLHCHVTDHIHAGMETTYTVLQNEDTKSG 1065
</PRE>
<PRE>
><a name = 2493322></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02493322&dopt=GenPept" >sp|Q61147|CERU_MOUSE</a> CERULOPLASMIN PRECURSOR (FERROXIDASE)
Length = 1062
Score = 1868 bits (4838), Expect = 0.0
Identities = 889/1067 (83%), Positives = 963/1067 (89%), Gaps = 7/1067 (0%)
Query: 1 MKILILGIFLFLCSTPAWAKEKHYYIGIIETTWDYASDHGEKKLISVDTEHSNIYLQNGP 60
MK L+L F+FL S+ A A++KHY+IGI E WDYAS EKKLISVDTE SN YLQNGP
Sbjct: 1 MKFLLLSTFIFLYSSLALARDKHYFIGITEAVWDYASGTEEKKLISVDTEQSNFYLQNGP 60
Query: 61 DRIGRLYKKALYLQYTDETFRTTIEKPVWLGFLGPIIKAETGDKVYVHLKNLASRPYTFH 120
DRIGR YKKALY +YTD TF TI+KP WLGFLGP+IKAE DKVYVHLKNLASR YTFH
Sbjct: 61 DRIGRKYKKALYFEYTDGTFSKTIDKPAWLGFLGPVIKAEVEDKVYVHLKNLASRIYTFH 120
Query: 121 SHGITYYKEHEGAIYPDNTTDFQRADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYH 180
+HG+TY KE+EGA+YPDNTTDFQRADDKV PG+QY Y+L A E SPGEGD NCVTRIYH
Sbjct: 121 AHGVTYTKEYEGAVYPDNTTDFQRADDKVLPGQQYVYVLHANEP-SPGEGDSNCVTRIYH 179
Query: 181 SHIDAPKDIASGLIGPLIICKKDSLDKEKEKHIDREFVVMFSVVDENFSWYLEDNIKTYC 240
SH+DAPKDIASGLIGPLI+CKK SL KEKEK+ID+EFV+MFSVVDEN SWYLEDNIKT+C
Sbjct: 180 SHVDAPKDIASGLIGPLILCKKGSLYKEKEKNIDQEFVLMFSVVDENLSWYLEDNIKTFC 239
Query: 241 SEPEKVDKDNEDFQESNRMYSVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFH 300
SEPEKVDKDNEDFQESNRMYS+NGYTFGSLPGLSMCA DRVKWYLFGMGNEVDVH+AFFH
Sbjct: 240 SEPEKVDKDNEDFQESNRMYSINGYTFGSLPGLSMCAADRVKWYLFGMGNEVDVHSAFFH 299
Query: 301 GQALTNKNYRIDTINLFPATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQVQECNKS 360
GQALT++NY+ D INLFPATL DAYMVAQNPG WMLSCQNLNHLKAGLQAFFQVQ+CNK
Sbjct: 300 GQALTSRNYQTDIINLFPATLIDAYMVAQNPGVWMLSCQNLNHLKAGLQAFFQVQDCNKP 359
Query: 361 SSKDNIRGKHVRHYYIAAEEIIWNYAPSGIDIFTKENLTAPGSDSAVFFEQGTTRIGGSY 420
SSKDNIRGKHVRHYYIAAEE+IWNYAPSGIDIFT+E LTA GSDS VFFEQG TRIGGSY
Sbjct: 360 SSKDNIRGKHVRHYYIAAEEVIWNYAPSGIDIFTEEKLTASGSDSGVFFEQGATRIGGSY 419
Query: 421 KKLVYREYTDASFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGV 480
KK+ YREYTD SFTNRKERGP+EEHLGILGPVIWAEVGDTI+VTFHNKG + LSI+P+GV
Sbjct: 420 KKMAYREYTDGSFTNRKERGPDEEHLGILGPVIWAEVGDTIKVTFHNKGQHHLSIQPMGV 479
Query: 481 RFNKNNEGTYYSPNYNPQSRSVPPSASHVAPTETFTYEWTVPKEVGPTNADPVCLAKMYY 540
F NEGTY Y P S +ASHVAP TFTYEWTVPKE+GPT ADPVCL+KMYY
Sbjct: 480 SFTAENEGTY----YGPPGASSQQAASHVAPKXTFTYEWTVPKEMGPTYADPVCLSKMYY 535
Query: 541 SAVDPTKDIFTGLIGPMKICKKGSLHANGRQKDVDKEFYLFPTVFDENESLLLEDNIRMF 600
SAVDPTKDIFTGLIGPMKICKKGSL A+GRQKDVDKEFYLFPTVFDENESLLL+DNIRMF
Sbjct: 536 SAVDPTKDIFTGLIGPMKICKKGSLLADGRQKDVDKEFYLFPTVFDENESLLLDDNIRMF 595
Query: 601 TTAPDQVDKEDEDFQESNKMHSMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGIYF 660
T APDQVDKEDEDFQESNKMHSMNGFMYGNQ MC G+S+VWYLFSAGNEADVHGIYF
Sbjct: 596 THAPDQVDKEDEDFQESNKMHSMNGFMYGNQSWPHMCLGESIVWYLFSAGNEADVHGIYF 655
Query: 661 SGNTYLWRGERRDTANLFPQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTVNQCRR 720
SGNTYL +GE RDTANLFP SLTL M PDT+GTF+VECLTTDHYTGGMKQKYTVNQC+R
Sbjct: 656 SGNTYLCKGEERDTANLFPHKSLTLLMNPDTKGTFDVECLTTDHYTGGMKQKYTVNQCQR 715
Query: 721 QSEDSTFYLGERTYYIAAVEVEWDYSPQREWEKELHHLQEQNVSNAFLDKGEFYIGSKYK 780
Q ED T YLGERTYY+ AVEVEWDYSP R WEKELHHLQEQNVSN FLDK EF+IGSKYK
Sbjct: 716 QFEDFTVYLGERTYYVDAVEVEWDYSPSRAWEKELHHLQEQNVSNVFLDKEEFFIGSKYK 775
Query: 781 KVVYRQYTDSTFRVPVERKAEE-EHLGILGPQLHADVGDKVKIIFKNMATRPYSIHAHGV 839
KVVYRQ+TDS+FR V+R+AEE EHLGILGP +HA+VGDKVK++FKNMATRPYSIHAHGV
Sbjct: 776 KVVYRQFTDSSFREQVKRRAEEDEHLGILGPPIHANVGDKVKVVFKNMATRPYSIHAHGV 835
Query: 840 QTESSTVTPTLPGETLTYVWKIPERSGAGTEDSACIPWAYYSTVDQVKDLYSGLIGPLIV 899
+TESSTV PTLPGE TY W+IPERSGAG EDSACIPWAYYSTVD+VKDLYSGLIGPLIV
Sbjct: 836 KTESSTVVPTLPGEVATYTWQIPERSGAGREDSACIPWAYYSTVDRVKDLYSGLIGPLIV 895
Query: 900 CRRPYLKVFNPRRKLEFALLFLVFDENESWYLDDNIKTYSDHPEKVNKDDEEFIESNKMH 959
CR+ Y+KVF+P++K+EF LLFLVFDENESWYLDDNIKTYS+HPEKVNKD+EEF+ESNKMH
Sbjct: 896 CRKSYVKVFSPKKKMEFFLLFLVFDENESWYLDDNIKTYSEHPEKVNKDNEEFLESNKMH 955
Query: 960 AINGRMFGNLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRGVYSSDVFDIF 1019
AING+MFGNLQGLTMHV DEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRGVYSSDVFD+F
Sbjct: 956 AINGKMFGNLQGLTMHVKDEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRGVYSSDVFDLF 1015
Query: 1020 PGTYQTLEMFPRTPGIWLLHCHVTDHIHAGMETTYTVLQ-NEDTKSG 1065
PGTYQTLEMFP+TPG WLLHCHVTDH+HAGM TTYTVL ++TKSG
Sbjct: 1016 PGTYQTLEMFPQTPGTWLLHCHVTDHVHAGMATTYTVLPVEQETKSG 1062
</PRE>
<PRE>
><a name = 2506226></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02506226&dopt=GenPept" >sp|P13635|CERU_RAT</a> CERULOPLASMIN PRECURSOR (FERROXIDASE)
Length = 1059
Score = 1851 bits (4794), Expect = 0.0
Identities = 874/1065 (82%), Positives = 953/1065 (89%), Gaps = 6/1065 (0%)
Query: 1 MKILILGIFLFLCSTPAWAKEKHYYIGIIETTWDYASDHGEKKLISVDTEHSNIYLQNGP 60
MK L+L LFL S+ AW +EKHYYIGI E WDYAS EK+LISVDTE SN YL+NGP
Sbjct: 1 MKFLLLSALLFLHSSLAWTREKHYYIGITEAVWDYASGSEEKELISVDTEQSNFYLRNGP 60
Query: 61 DRIGRLYKKALYLQYTDETFRTTIEKPVWLGFLGPIIKAETGDKVYVHLKNLASRPYTFH 120
DRIGR YKKALY +YTD TF TI+KP WLGFLGP+IKAE GDKV VH+KN ASRPYTFH
Sbjct: 61 DRIGRKYKKALYSEYTDGTFTKTIDKPAWLGFLGPVIKAEVGDKVSVHVKNFASRPYTFH 120
Query: 121 SHGITYYKEHEGAIYPDNTTDFQRADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYH 180
+HG+TY K +EGAIYPDNTTDFQRADDK++PG+QY Y+L A E SPGEGD NCVTRIYH
Sbjct: 121 AHGVTYTKANEGAIYPDNTTDFQRADDKLFPGQQYLYVLRANEP-SPGEGDSNCVTRIYH 179
Query: 181 SHIDAPKDIASGLIGPLIICKKDSLDKEKEKHIDREFVVMFSVVDENFSWYLEDNIKTYC 240
SH+DAPKDIASGLIGPLI+CKK SL KEKE++ID+EFV+MFSVVDEN SWYLEDNIKT+C
Sbjct: 180 SHVDAPKDIASGLIGPLILCKKGSLHKEKEENIDQEFVLMFSVVDENLSWYLEDNIKTFC 239
Query: 241 SEPEKVDKDNEDFQESNRMYSVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFH 300
SEPEKVDKDNEDFQESNRMYS+NGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVH+ FH
Sbjct: 240 SEPEKVDKDNEDFQESNRMYSINGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHSELFH 299
Query: 301 GQALTNKNYRIDTINLFPATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQVQECNKS 360
GQALT+KNY D INLFPATL D MVAQNPG WMLSCQNLNHLKAGLQAFFQV++CNK
Sbjct: 300 GQALTSKNYHTDIINLFPATLIDVSMVAQNPGVWMLSCQNLNHLKAGLQAFFQVRDCNKP 359
Query: 361 SSKDNIRGKHVRHYYIAAEEIIWNYAPSGIDIFTKENLTAPGSDSAVFFEQGTTRIGGSY 420
S D+I+ +HVRHYYIAAEE IW+YAPSG D FT EN T+ GSDS VFFEQG TRIGGSY
Sbjct: 360 SPDDDIQDRHVRHYYIAAEETIWDYAPSGTDTFTGENFTSLGSDSRVFFEQGATRIGGSY 419
Query: 421 KKLVYREYTDASFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGV 480
KKLVYREYTD SFTNRKERGP+EEHLGILGPVIWAEVGD IRVTFHNKG +PLSI+P+GV
Sbjct: 420 KKLVYREYTDDSFTNRKERGPDEEHLGILGPVIWAEVGDIIRVTFHNKGQFPLSIQPMGV 479
Query: 481 RFNKNNEGTYYSPNYNPQSRSVPPSASHVAPTETFTYEWTVPKEVGPTNADPVCLAKMYY 540
RF K NEGTYY P+ + ASHVAP ETFTYEWTVPKE+GPT ADPVCL+KMYY
Sbjct: 480 RFTKENEGTYYGPDGRSSKQ-----ASHVAPKETFTYEWTVPKEMGPTYADPVCLSKMYY 534
Query: 541 SAVDPTKDIFTGLIGPMKICKKGSLHANGRQKDVDKEFYLFPTVFDENESLLLEDNIRMF 600
S VD TKDIFTGLIGPMKICKKGSL A+GRQKDVDKEFYLF TVFDENESLLL+DNIRMF
Sbjct: 535 SGVDLTKDIFTGLIGPMKICKKGSLLADGRQKDVDKEFYLFATVFDENESLLLDDNIRMF 594
Query: 601 TTAPDQVDKEDEDFQESNKMHSMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGIYF 660
TTAP+ VDKEDEDFQESNKMHSMNGFMYGN PGL MC G+S+VWYLFSAGNEADVHGIYF
Sbjct: 595 TTAPENVDKEDEDFQESNKMHSMNGFMYGNLPGLNMCLGESIVWYLFSAGNEADVHGIYF 654
Query: 661 SGNTYLWRGERRDTANLFPQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTVNQCRR 720
SGNTYL +GERRDTANLFP SLTL M PDTEG+F+VECLTTDHYTGGMKQKYTVNQC+
Sbjct: 655 SGNTYLSKGERRDTANLFPHKSLTLLMTPDTEGSFDVECLTTDHYTGGMKQKYTVNQCKG 714
Query: 721 QSEDSTFYLGERTYYIAAVEVEWDYSPQREWEKELHHLQEQNVSNAFLDKGEFYIGSKYK 780
Q ED T Y GERTYYIAAVEVEWDYSP R+WE ELHHLQEQNVSNAFLDK EF+IGSKYK
Sbjct: 715 QFEDVTLYQGERTYYIAAVEVEWDYSPSRDWEMELHHLQEQNVSNAFLDKEEFFIGSKYK 774
Query: 781 KVVYRQYTDSTFRVPVERKAEEEHLGILGPQLHADVGDKVKIIFKNMATRPYSIHAHGVQ 840
KVVYR++TDSTFR V+R+AEEEHLG+LGP +HADVG KVK++FKNMATRPYSIHAHGV+
Sbjct: 775 KVVYREFTDSTFREQVKRRAEEEHLGMLGPLIHADVGAKVKVVFKNMATRPYSIHAHGVK 834
Query: 841 TESSTVTPTLPGETLTYVWKIPERSGAGTEDSACIPWAYYSTVDQVKDLYSGLIGPLIVC 900
T+SSTV PTLPGE TY+W+IPERSGAGTEDS CIPWAYYSTVD+VKDLYSGLIGPLIVC
Sbjct: 835 TKSSTVAPTLPGEVRTYIWQIPERSGAGTEDSPCIPWAYYSTVDRVKDLYSGLIGPLIVC 894
Query: 901 RRPYLKVFNPRRKLEFALLFLVFDENESWYLDDNIKTYSDHPEKVNKDDEEFIESNKMHA 960
R+ Y+KVFNP++K+EF+LLFLVFDENESWYLDDNI TY DHPEK NKD+EEFIESNKMHA
Sbjct: 895 RKSYVKVFNPKKKMEFSLLFLVFDENESWYLDDNINTYPDHPEKDNKDNEEFIESNKMHA 954
Query: 961 INGRMFGNLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRGVYSSDVFDIFP 1020
ING+MFGNLQGLTMHVGDEVNWY+M MGNEIDLHTVHFHGHSFQYKHRG++SSDVFD FP
Sbjct: 955 INGKMFGNLQGLTMHVGDEVNWYVMAMGNEIDLHTVHFHGHSFQYKHRGIHSSDVFDFFP 1014
Query: 1021 GTYQTLEMFPRTPGIWLLHCHVTDHIHAGMETTYTVLQNEDTKSG 1065
GTYQTLEMFP+TPG WLLHCHVTDHIHAGM TTYTVL N++TKSG
Sbjct: 1015 GTYQTLEMFPQTPGTWLLHCHVTDHIHAGMVTTYTVLPNQETKSG 1059
</PRE>
<PRE>
><a name = 119767></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=00119767&dopt=GenPept" >sp|P00451|FA8_HUMAN</a> Coagulation factor VIII precursor (Procoagulant component)
(Antihemophilic factor) (AHF)
Length = 2351
Score = 426 bits (1096), Expect = e-119
Identities = 261/766 (34%), Positives = 391/766 (50%), Gaps = 81/766 (10%)
Query: 6 LGIFLFLCSTP-AWAKEKHYYIGIIETTWDY-ASDHGEKKLISVDTEHSNIYLQNGPDRI 63
L FLC ++ + YY+G +E +WDY SD GE + VD ++ P
Sbjct: 5 LSTCFFLCLLRFCFSATRRYYLGAVELSWDYMQSDLGE---LPVDARFPPRVPKSFPFNT 61
Query: 64 GRLYKKALYLQYTDETFRTTIEKPVWLGFLGPIIKAETGDKVYVHLKNLASRPYTFHSHG 123
+YKK L++++TD F +P W+G LGP I+AE D V + LKN+AS P + H+ G
Sbjct: 62 SVVYKKTLFVEFTDHLFNIAKPRPPWMGLLGPTIQAEVYDTVVITLKNMASHPVSLHAVG 121
Query: 124 ITYYKEHEGAIYPDNTTDFQRADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHI 183
++Y+K EGA Y D T+ ++ DDKV+PG +TY+ +E P D C+T Y SH+
Sbjct: 122 VSYWKASEGAEYDDQTSQREKEDDKVFPGGSHTYVWQVLKENGPMASDPLCLTYSYLSHV 181
Query: 184 DAPKDIASGLIGPLIICKKDSLDKEKEKHIDREFVVMFSVVDENFSWYLEDNIKTYCSEP 243
D KD+ SGLIG L++C++ SL KEK + + +F+++F+V DE SW+ E
Sbjct: 182 DLVKDLNSGLIGALLVCREGSLAKEKTQTL-HKFILLFAVFDEGKSWHSE------TKNS 234
Query: 244 EKVDKDNEDFQESNRMYSVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFHGQA 303
D+D + +M++VNGY SLPGL C V W++ GMG +VH+ F G
Sbjct: 235 LMQDRDAASARAWPKMHTVNGYVNRSLPGLIGCHRKSVYWHVIGMGTTPEVHSIFLEGHT 294
Query: 304 LTNKNYRIDTINLFPATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQVQEC------ 357
+N+R ++ + P T A + + G+++L C +H G++A+ +V C
Sbjct: 295 FLVRNHRQASLEISPITFLTAQTLLMDLGQFLLFCHISSHQHDGMEAYVKVDSCPEEPQL 354
Query: 358 ---NKSSSKD------------------------NIRGKHVRH-----YYIAAEEIIWNY 385
N ++D IR +H +YIAAEE W+Y
Sbjct: 355 RMKNNEEAEDYDDDLTDSEMDVVRFDDDNSPSFIQIRSVAKKHPKTWVHYIAAEEEDWDY 414
Query: 386 APSGIDIFTKENLTAPGSDS--AVFFEQGTTRIGGSYKKLVYREYTDASFTNRKERGPEE 443
AP + AP S + + G RIG YKK+ + YTD +F K R +
Sbjct: 415 APL---------VLAPDDRSYKSQYLNNGPQRIGRKYKKVRFMAYTDETF---KTREAIQ 462
Query: 444 EHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGVRFNKNNEGTYYSPNYNPQSRSVP 503
GILGP+++ EVGDT+ + F N+ + P +I P G+ T P Y SR +P
Sbjct: 463 HESGILGPLLYGEVGDTLLIIFKNQASRPYNIYPHGI--------TDVRPLY---SRRLP 511
Query: 504 PSASH-----VAPTETFTYEWTVPKEVGPTNADPVCLAKMYYSAVDPTKDIFTGLIGPMK 558
H + P E F Y+WTV E GPT +DP CL + Y S V+ +D+ +GLIGP+
Sbjct: 512 KGVKHLKDFPILPGEIFKYKWTVTVEDGPTKSDPRCLTRYYSSFVNMERDLASGLIGPLL 571
Query: 559 ICKKGSLHANGRQKDVDKEFYLFPTVFDENESLLLEDNIRMFTTAPDQVDKEDEDFQESN 618
IC K S+ G Q DK + +VFDEN S L +NI+ F P V ED +FQ SN
Sbjct: 572 ICYKESVDQRGNQIMSDKRNVILFSVFDENRSWYLTENIQRFLPNPAGVQLEDPEFQASN 631
Query: 619 KMHSMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGIYFSGNTYLWRGERRDTANLF 678
MHS+NG+++ + L++C + WY+ S G + D ++FSG T+ + DT LF
Sbjct: 632 IMHSINGYVFDSLQ-LSVCLHEVAYWYILSIGAQTDFLSVFFSGYTFKHKMVYEDTLTLF 690
Query: 679 PQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTVNQCRRQSED 724
P + T+ M + G + + C +D GM V+ C + + D
Sbjct: 691 PFSGETVFMSMENPGLWILGCHNSDFRNRGMTALLKVSSCDKNTGD 736
</PRE>
<PRE>
Score = 369 bits (948), Expect = e-101
Identities = 241/736 (32%), Positives = 367/736 (49%), Gaps = 93/736 (12%)
Query: 372 RHYYIAAEEIIWNYAPSGIDIFTKENLTAPGSDSAVFFEQGTTRIGGSYKKLVYREYTDA 431
R YY+ A E+ W+Y S + + P + F YKK ++ E+TD
Sbjct: 22 RRYYLGAVELSWDYMQSDLGELPVDARFPPRVPKSFPFNTSVV-----YKKTLFVEFTDH 76
Query: 432 SFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGVRFNKNNEGTYY 491
F K R P +G+LGP I AEV DT+ +T N ++P+S+ +GV + K +EG
Sbjct: 77 LFNIAKPRPP---WMGLLGPTIQAEVYDTVVITLKNMASHPVSLHAVGVSYWKASEGA-- 131
Query: 492 SPNYNPQSRSVPPSASHVAPTETFTYEWTVPKEVGPTNADPVCLAKMYYSAVDPTKDIFT 551
Y+ Q+ V P + TY W V KE GP +DP+CL Y S VD KD+ +
Sbjct: 132 --EYDDQTSQREKEDDKVFPGGSHTYVWQVLKENGPMASDPLCLTYSYLSHVDLVKDLNS 189
Query: 552 GLIGPMKICKKGSLHANGRQKDVDKEFYLFPTVFDENESLLLEDNIRMFTTAPDQVDKED 611
GLIG + +C++GSL A + + + K LF VFDE +S E + D++
Sbjct: 190 GLIGALLVCREGSL-AKEKTQTLHKFILLF-AVFDEGKSWHSETKNSLMQ------DRDA 241
Query: 612 EDFQESNKMHSMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGIYFSGNTYLWRGER 671
+ KMH++NG++ + PGL C SV W++ G +VH I+ G+T+L R R
Sbjct: 242 ASARAWPKMHTVNGYVNRSLPGLIGCHRKSVYWHVIGMGTTPEVHSIFLEGHTFLVRNHR 301
Query: 672 RDTANLFPQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTVNQC-------RRQSED 724
+ + + P T LT G F + C + H GM+ V+ C + +E+
Sbjct: 302 QASLEISPITFLTAQTLLMDLGQFLLFCHISSHQHDGMEAYVKVDSCPEEPQLRMKNNEE 361
Query: 725 STFYLGERT--------------------------------YYIAAVEVEWDYSPQREWE 752
+ Y + T +YIAA E +WDY+P
Sbjct: 362 AEDYDDDLTDSEMDVVRFDDDNSPSFIQIRSVAKKHPKTWVHYIAAEEEDWDYAPL---- 417
Query: 753 KELHHLQEQNVSNAFLDKGEFYIGSKYKKVVYRQYTDSTFRVPVERKAEEEHLGILGPQL 812
+ +++ + +L+ G IG KYKKV + YTD TF+ R+A + GILGP L
Sbjct: 418 --VLAPDDRSYKSQYLNNGPQRIGRKYKKVRFMAYTDETFKT---REAIQHESGILGPLL 472
Query: 813 HADVGDKVKIIFKNMATRPYSIHAHGVQTESSTVT-------------PTLPGETLTYVW 859
+ +VGD + IIFKN A+RPY+I+ HG+ + P LPGE Y W
Sbjct: 473 YGEVGDTLLIIFKNQASRPYNIYPHGITDVRPLYSRRLPKGVKHLKDFPILPGEIFKYKW 532
Query: 860 KIPERSGAGTEDSACIPWAYYSTVDQVKDLYSGLIGPLIVCRRPYL-----KVFNPRRKL 914
+ G D C+ Y S V+ +DL SGLIGPL++C + + ++ + +R +
Sbjct: 533 TVTVEDGPTKSDPRCLTRYYSSFVNMERDLASGLIGPLLICYKESVDQRGNQIMSDKRNV 592
Query: 915 EFALLFLVFDENESWYLDDNIKTYSDHPEKVNKDDEEFIESNKMHAINGRMFGNLQGLTM 974
+LF VFDEN SWYL +NI+ + +P V +D EF SN MH+ING +F +LQ L++
Sbjct: 593 ---ILFSVFDENRSWYLTENIQRFLPNPAGVQLEDPEFQASNIMHSINGYVFDSLQ-LSV 648
Query: 975 HVGDEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRGVYSSDVFDIFPGTYQTLEMFPRTPG 1034
+ + WY++ +G + D +V F G++F KH+ VY D +FP + +T+ M PG
Sbjct: 649 CLHEVAYWYILSIGAQTDFLSVFFSGYTF--KHKMVY-EDTLTLFPFSGETVFMSMENPG 705
Query: 1035 IWLLHCHVTDHIHAGM 1050
+W+L CH +D + GM
Sbjct: 706 LWILGCHNSDFRNRGM 721
</PRE>
<PRE>
Score = 248 bits (632), Expect = 5e-65
Identities = 132/339 (38%), Positives = 188/339 (54%), Gaps = 8/339 (2%)
Query: 24 YYIGIIETTWDYASDHGEKKLISVDTEHSNIYLQNGPDRIGRLYKKALYLQYTDETFRTT 83
+YI E WDYA L D + + YL NGP RIGR YKK ++ YTDETF+T
Sbjct: 403 HYIAAEEEDWDYAP----LVLAPDDRSYKSQYLNNGPQRIGRKYKKVRFMAYTDETFKTR 458
Query: 84 IEKPVWLGFLGPIIKAETGDKVYVHLKNLASRPYTFHSHGITYYKEHEGAIYPDNTTDFQ 143
G LGP++ E GD + + KN ASRPY + HGIT + P +
Sbjct: 459 EAIQHESGILGPLLYGEVGDTLLIIFKNQASRPYNIYPHGITDVRPLYSRRLPKGVKHLK 518
Query: 144 RADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASGLIGPLIICKKD 203
D + PGE + Y T E P + D C+TR Y S ++ +D+ASGLIGPL+IC K+
Sbjct: 519 --DFPILPGEIFKYKWTVTVEDGPTKSDPRCLTRYYSSFVNMERDLASGLIGPLLICYKE 576
Query: 204 SLDKEKEKHI-DREFVVMFSVVDENFSWYLEDNIKTYCSEPEKVDKDNEDFQESNRMYSV 262
S+D+ + + D+ V++FSV DEN SWYL +NI+ + P V ++ +FQ SN M+S+
Sbjct: 577 SVDQRGNQIMSDKRNVILFSVFDENRSWYLTENIQRFLPNPAGVQLEDPEFQASNIMHSI 636
Query: 263 NGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFHGQALTNKNYRIDTINLFPATLF 322
NGY F SL LS+C + WY+ +G + D + FF G +K DT+ LFP +
Sbjct: 637 NGYVFDSLQ-LSVCLHEVAYWYILSIGAQTDFLSVFFSGYTFKHKMVYEDTLTLFPFSGE 695
Query: 323 DAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQVQECNKSS 361
+M +NPG W+L C N + G+ A +V C+K++
Sbjct: 696 TVFMSMENPGLWILGCHNSDFRNRGMTALLKVSSCDKNT 734
</PRE>
<PRE>
Score = 243 bits (619), Expect = 2e-63
Identities = 125/360 (34%), Positives = 193/360 (52%), Gaps = 22/360 (6%)
Query: 710 KQKYTVNQCRRQSEDSTFYLGERTYYIAAVEVEWDYSPQREWEKELHHLQEQNVSNAFLD 769
K+ + + +F R Y+IAAVE WDY H L+ + S +
Sbjct: 1693 KEDFDIYDEDENQSPRSFQKKTRHYFIAAVERLWDYG----MSSSPHVLRNRAQSGSV-- 1746
Query: 770 KGEFYIGSKYKKVVYRQYTDSTFRVPVERKAEEEHLGILGPQLHADVGDKVKIIFKNMAT 829
++KKVV++++TD +F P+ R EHLG+LGP + A+V D + + F+N A+
Sbjct: 1747 -------PQFKKVVFQEFTDGSFTQPLYRGELNEHLGLLGPYIRAEVEDNIMVTFRNQAS 1799
Query: 830 RPYSIHAHGVQTESST---VTP----TLPGETLTYVWKIPERSGAGTEDSACIPWAYYST 882
RPYS ++ + E P P ET TY WK+ ++ C WAY+S
Sbjct: 1800 RPYSFYSSLISYEEDQRQGAEPRKNFVKPNETKTYFWKVQHHMAPTKDEFDCKAWAYFSD 1859
Query: 883 VDQVKDLYSGLIGPLIVCRRPYLKVFNPRRKL--EFALLFLVFDENESWYLDDNIKTYSD 940
VD KD++SGLIGPL+VC L + R+ EFAL F +FDE +SWY +N++
Sbjct: 1860 VDLEKDVHSGLIGPLLVCHTNTLNPAHGRQVTVQEFALFFTIFDETKSWYFTENMERNCR 1919
Query: 941 HPEKVNKDDEEFIESNKMHAINGRMFGNLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHG 1000
P + +D F E+ + HAING + L GL M + WYL+ MG+ ++H++HF G
Sbjct: 1920 APCNIQMEDPTFKENYRFHAINGYIMDTLPGLVMAQDQRIRWYLLSMGSNENIHSIHFSG 1979
Query: 1001 HSFQYKHRGVYSSDVFDIFPGTYQTLEMFPRTPGIWLLHCHVTDHIHAGMETTYTVLQNE 1060
H F + + Y +++++PG ++T+EM P GIW + C + +H+HAGM T + V N+
Sbjct: 1980 HVFTVRKKEEYKMALYNLYPGVFETVEMLPSKAGIWRVECLIGEHLHAGMSTLFLVYSNK 2039
</PRE>
<PRE>
Score = 211 bits (537), Expect = 6e-54
Identities = 126/357 (35%), Positives = 185/357 (51%), Gaps = 33/357 (9%)
Query: 369 KHVRHYYIAAEEIIWNYAPSGIDIFTKENLTAPGSDSAVFFEQGTTRIGGSYKKLVYREY 428
K RHY+IAA E +W+Y S S V + + +KK+V++E+
Sbjct: 1712 KKTRHYFIAAVERLWDYGMS--------------SSPHVLRNRAQSGSVPQFKKVVFQEF 1757
Query: 429 TDASFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGVRFNKNNEG 488
TD SFT RG EHLG+LGP I AEV D I VTF N+ + P S + + ++
Sbjct: 1758 TDGSFTQPLYRGELNEHLGLLGPYIRAEVEDNIMVTFRNQASRPYSFYSSLISYEED--- 1814
Query: 489 TYYSPNYNPQSRSVPPSASHVAPTETFTYEWTVPKEVGPTNADPVCLAKMYYSAVDPTKD 548
Q + P + V P ET TY W V + PT + C A Y+S VD KD
Sbjct: 1815 ---------QRQGAEPRKNFVKPNETKTYFWKVQHHMAPTKDEFDCKAWAYFSDVDLEKD 1865
Query: 549 IFTGLIGPMKICKKGSLH-ANGRQKDVDKEFYLFPTVFDENESLLLEDNIRMFTTAPDQV 607
+ +GLIGP+ +C +L+ A+GRQ V +EF LF T+FDE +S +N+ AP +
Sbjct: 1866 VHSGLIGPLLVCHTNTLNPAHGRQVTV-QEFALFFTIFDETKSWYFTENMERNCRAPCNI 1924
Query: 608 DKEDEDFQESNKMHSMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGIYFSGNTYLW 667
ED F+E+ + H++NG++ PGL M + + WYL S G+ ++H I+FSG+ +
Sbjct: 1925 QMEDPTFKENYRFHAINGYIMDTLPGLVMAQDQRIRWYLLSMGSNENIHSIHFSGHVFTV 1984
Query: 668 RGE---RRDTANLFPQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTV--NQCR 719
R + + NL+P T+ M P G + VECL +H GM + V N+C+
Sbjct: 1985 RKKEEYKMALYNLYPGVFETVEMLPSKAGIWRVECLIGEHLHAGMSTLFLVYSNKCQ 2041
</PRE>
<PRE>
Score = 197 bits (501), Expect = 8e-50
Identities = 112/377 (29%), Positives = 183/377 (47%), Gaps = 31/377 (8%)
Query: 20 KEKHYYIGIIETTWDYASDHGEKKLISVDTEHSNIYLQNGPDRIGRL--YKKALYLQYTD 77
K +HY+I +E WDY S+ ++ + G + +KK ++ ++TD
Sbjct: 1713 KTRHYFIAAVERLWDYGMS-------------SSPHVLRNRAQSGSVPQFKKVVFQEFTD 1759
Query: 78 ETFRTTI---EKPVWLGFLGPIIKAETGDKVYVHLKNLASRPYTFHSHGITYYKEHEGAI 134
+F + E LG LGP I+AE D + V +N ASRPY+F+S I+Y ++
Sbjct: 1760 GSFTQPLYRGELNEHLGLLGPYIRAEVEDNIMVTFRNQASRPYSFYSSLISYEEDQRQGA 1819
Query: 135 YPDNTTDFQRADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASGLI 194
P V P E TY +P + + +C Y S +D KD+ SGLI
Sbjct: 1820 EPRKNF--------VKPNETKTYFWKVQHHMAPTKDEFDCKAWAYFSDVDLEKDVHSGLI 1871
Query: 195 GPLIICKKDSLDKEKEKHID-REFVVMFSVVDENFSWYLEDNIKTYCSEPEKVDKDNEDF 253
GPL++C ++L+ + + +EF + F++ DE SWY +N++ C P + ++ F
Sbjct: 1872 GPLLVCHTNTLNPAHGRQVTVQEFALFFTIFDETKSWYFTENMERNCRAPCNIQMEDPTF 1931
Query: 254 QESNRMYSVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFHGQALT---NKNYR 310
+E+ R +++NGY +LPGL M + R++WYL MG+ ++H+ F G T + Y+
Sbjct: 1932 KENYRFHAINGYIMDTLPGLVMAQDQRIRWYLLSMGSNENIHSIHFSGHVFTVRKKEEYK 1991
Query: 311 IDTINLFPATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQVQECNKSSSKDNIRGKH 370
+ NL+P M+ G W + C HL AG+ F V NK + + H
Sbjct: 1992 MALYNLYPGVFETVEMLPSKAGIWRVECLIGEHLHAGMSTLFLVYS-NKCQTPLGMASGH 2050
Query: 371 VRHYYIAAEEIIWNYAP 387
+R + I A +AP
Sbjct: 2051 IRDFQITASGQYGQWAP 2067
</PRE>
<PRE>
Score = 171 bits (432), Expect = 8e-42
Identities = 110/335 (32%), Positives = 161/335 (47%), Gaps = 31/335 (9%)
Query: 732 RTYYIAAVEVEWDYSPQREWEKELHHLQEQNVSNAFLDKGEFYIGSKYKKVVYRQYTDST 791
R YY+ AVE+ WDY E + V +F F YKK ++ ++TD
Sbjct: 22 RRYYLGAVELSWDYMQSDLGELPVDARFPPRVPKSF----PFNTSVVYKKTLFVEFTDHL 77
Query: 792 FRVPVERKAEEEHLGILGPQLHADVGDKVKIIFKNMATRPYSIHAHGVQTESSTV----- 846
F + K +G+LGP + A+V D V I KNMA+ P S+HA GV ++
Sbjct: 78 FNIA---KPRPPWMGLLGPTIQAEVYDTVVITLKNMASHPVSLHAVGVSYWKASEGAEYD 134
Query: 847 ----------TPTLPGETLTYVWKIPERSGAGTEDSACIPWAYYSTVDQVKDLYSGLIGP 896
PG + TYVW++ + +G D C+ ++Y S VD VKDL SGLIG
Sbjct: 135 DQTSQREKEDDKVFPGGSHTYVWQVLKENGPMASDPLCLTYSYLSHVDLVKDLNSGLIGA 194
Query: 897 LIVCRRPYLKVFNPRRKLEFALLFLVFDENESWYLDDNIKTYSDHPEKVNKDDEEFIESN 956
L+VCR L + +F LLF VFDE +SW+ + D +D
Sbjct: 195 LLVCREGSLAKEKTQTLHKFILLFAVFDEGKSWHSETKNSLMQD------RDAASARAWP 248
Query: 957 KMHAINGRMFGNLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRGVYSSDVF 1016
KMH +NG + +L GL V W+++GMG ++H++ GH+F ++ S
Sbjct: 249 KMHTVNGYVNRSLPGLIGCHRKSVYWHVIGMGTTPEVHSIFLEGHTFLVRNHRQAS---L 305
Query: 1017 DIFPGTYQTLEMFPRTPGIWLLHCHVTDHIHAGME 1051
+I P T+ T + G +LL CH++ H H GME
Sbjct: 306 EISPITFLTAQTLLMDLGQFLLFCHISSHQHDGME 340
</PRE>
<PRE>
><a name = 544272></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=00544272&dopt=GenPept" >sp|Q06194|FA8_MOUSE</a> Coagulation factor VIII precursor (Procoagulant component)
Length = 2319
Score = 417 bits (1072), Expect = e-116
Identities = 250/769 (32%), Positives = 395/769 (50%), Gaps = 78/769 (10%)
Query: 1 MKILILGIFLFLCSTPAWAKEKHYYIGIIETTWDYASDHGEKKLISV---DTEHSNIYLQ 57
M+I + F + + YY+G +E +W+Y + L+SV D+
Sbjct: 1 MQIALFACFFLSLFNFCSSAIRRYYLGAVELSWNYI----QSDLLSVLHTDSRFLPRMST 56
Query: 58 NGPDRIGRLYKKALYLQYTDETFRTTIEKPVWLGFLGPIIKAETGDKVYVHLKNLASRPY 117
+ P +YKK ++++Y D+ F +P W+G LGP I E D V + LKN+AS P
Sbjct: 57 SFPFNTSIMYKKTVFVEYKDQLFNIAKPRPPWMGLLGPTIWTEVHDTVVITLKNMASHPV 116
Query: 118 TFHSHGITYYKEHEGAIYPDNTTDFQRADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTR 177
+ H+ G++Y+K EG Y D T+ ++ DDKV+PGE +TY+ +E P D C+T
Sbjct: 117 SLHAVGVSYWKASEGDEYEDQTSQMEKEDDKVFPGESHTYVWQVLKENGPMASDPPCLTY 176
Query: 178 IYHSHIDAPKDIASGLIGPLIICKKDSLDKEKEKHIDREFVVMFSVVDENFSWYLEDNIK 237
Y SH+D KD+ SGLIG L++CK+ SL KE+ + + +FV++F+V DE SW+ E N
Sbjct: 177 SYMSHVDLVKDLNSGLIGALLVCKEGSLSKERTQML-YQFVLLFAVFDEGKSWHSETN-- 233
Query: 238 TYCSEPEKVDKDNEDFQESNRMYSVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAA 297
+ D+ ++ +M++VNGY SLPGL C V W++ GMG ++H+
Sbjct: 234 ----DSYTQSMDSASARDWPKMHTVNGYVNRSLPGLIGCHRKSVYWHVIGMGTTPEIHSI 289
Query: 298 FFHGQALTNKNYRIDTINLFPATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQVQEC 357
F G +N+R ++ + P T A + + G+++L C +H G++A+ +V C
Sbjct: 290 FLEGHTFFVRNHRQASLEISPITFLTAQTLLIDLGQFLLFCHISSHKHDGMEAYVKVDSC 349
Query: 358 NKSS---SKDN-----------------------------IRGKHVRH-----YYIAAEE 380
+ S K+N IR ++ +YI+AEE
Sbjct: 350 PEESQWQKKNNNEEMEDYDDDLYSEMDMFTLDYDSSPFIQIRSVAKKYPKTWIHYISAEE 409
Query: 381 IIWNYAPSGIDIFTKENLTAPGSDSAVFFEQGTTRIGGSYKKLVYREYTDASFTNRKERG 440
W+YAPS + T +N GS + + G RIG YKK+ + YTD +F K R
Sbjct: 410 EDWDYAPS---VPTSDN----GSYKSQYLSNGPHRIGRKYKKVRFIAYTDETF---KTRE 459
Query: 441 PEEEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGVRFNKNNEGTYYSPNYNPQSR 500
+ G+LGP+++ EVGDT+ + F N+ + P +I P G+ T SP + +R
Sbjct: 460 TIQHESGLLGPLLYGEVGDTLLIIFKNQASRPYNIYPHGI--------TDVSPLH---AR 508
Query: 501 SVPPSASHVA-----PTETFTYEWTVPKEVGPTNADPVCLAKMYYSAVDPTKDIFTGLIG 555
+P HV P E F Y+WTV E GPT +DP CL + Y S ++P +D+ +GLIG
Sbjct: 509 RLPRGIKHVKDLPIHPGEIFKYKWTVTVEDGPTKSDPRCLTRYYSSFINPERDLASGLIG 568
Query: 556 PMKICKKGSLHANGRQKDVDKEFYLFPTVFDENESLLLEDNIRMFTTAPDQVDKEDEDFQ 615
P+ IC K S+ G Q DK + ++FDEN+S + +N++ F + +D FQ
Sbjct: 569 PLLICYKESVDQRGNQMMSDKRNVILFSIFDENQSWYITENMQRFLPNAAKTQPQDPGFQ 628
Query: 616 ESNKMHSMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGIYFSGNTYLWRGERRDTA 675
SN MHS+NG+++ + LT+C + W++ S G + D I+FSG T+ + DT
Sbjct: 629 ASNIMHSINGYVFDSLE-LTVCLHEVAYWHILSVGAQTDFLSIFFSGYTFKHKMVYEDTL 687
Query: 676 NLFPQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTVNQCRRQSED 724
LFP + T+ M + G + + C +D GM V+ C + + D
Sbjct: 688 TLFPFSGETVFMSMENPGLWVLGCHNSDFRKRGMTALLKVSSCDKSTSD 736
</PRE>
<PRE>
Score = 366 bits (940), Expect = e-100
Identities = 236/743 (31%), Positives = 363/743 (48%), Gaps = 93/743 (12%)
Query: 365 NIRGKHVRHYYIAAEEIIWNYAPSGI-DIFTKENLTAPGSDSAVFFEQGTTRIGGSYKKL 423
N +R YY+ A E+ WNY S + + ++ P ++ F YKK
Sbjct: 15 NFCSSAIRRYYLGAVELSWNYIQSDLLSVLHTDSRFLPRMSTSFPFNTSIM-----YKKT 69
Query: 424 VYREYTDASFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGVRFN 483
V+ EY D F K R P +G+LGP IW EV DT+ +T N ++P+S+ +GV +
Sbjct: 70 VFVEYKDQLFNIAKPRPP---WMGLLGPTIWTEVHDTVVITLKNMASHPVSLHAVGVSYW 126
Query: 484 KNNEGTYYSPNYNPQSRSVPPSASHVAPTETFTYEWTVPKEVGPTNADPVCLAKMYYSAV 543
K +EG Y Q+ + V P E+ TY W V KE GP +DP CL Y S V
Sbjct: 127 KASEGD----EYEDQTSQMEKEDDKVFPGESHTYVWQVLKENGPMASDPPCLTYSYMSHV 182
Query: 544 DPTKDIFTGLIGPMKICKKGSLHANGRQKDVDKEFYLFPTVFDENESLLLEDNIRMFTTA 603
D KD+ +GLIG + +CK+GSL Q + +F L VFDE +S E N +T +
Sbjct: 183 DLVKDLNSGLIGALLVCKEGSLSKERTQ--MLYQFVLLFAVFDEGKSWHSETN-DSYTQS 239
Query: 604 PDQVDKEDEDFQESNKMHSMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGIYFSGN 663
D D KMH++NG++ + PGL C SV W++ G ++H I+ G+
Sbjct: 240 MDSASARDWP-----KMHTVNGYVNRSLPGLIGCHRKSVYWHVIGMGTTPEIHSIFLEGH 294
Query: 664 TYLWRGERRDTANLFPQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTVNQCRRQSE 723
T+ R R+ + + P T LT G F + C + H GM+ V+ C +S+
Sbjct: 295 TFFVRNHRQASLEISPITFLTAQTLLIDLGQFLLFCHISSHKHDGMEAYVKVDSCPEESQ 354
Query: 724 ----------------------------DSTFYLGERT----------YYIAAVEVEWDY 745
DS+ ++ R+ +YI+A E +WDY
Sbjct: 355 WQKKNNNEEMEDYDDDLYSEMDMFTLDYDSSPFIQIRSVAKKYPKTWIHYISAEEEDWDY 414
Query: 746 SPQREWEKELHHLQEQNVSNAFLDKGEFYIGSKYKKVVYRQYTDSTFRVPVERKAEEEHL 805
+P + + + +L G IG KYKKV + YTD TF+ R+ +
Sbjct: 415 APS------VPTSDNGSYKSQYLSNGPHRIGRKYKKVRFIAYTDETFKT---RETIQHES 465
Query: 806 GILGPQLHADVGDKVKIIFKNMATRPYSIHAHGVQTESSTVT-------------PTLPG 852
G+LGP L+ +VGD + IIFKN A+RPY+I+ HG+ S P PG
Sbjct: 466 GLLGPLLYGEVGDTLLIIFKNQASRPYNIYPHGITDVSPLHARRLPRGIKHVKDLPIHPG 525
Query: 853 ETLTYVWKIPERSGAGTEDSACIPWAYYSTVDQVKDLYSGLIGPLIVCRRPYL-----KV 907
E Y W + G D C+ Y S ++ +DL SGLIGPL++C + + ++
Sbjct: 526 EIFKYKWTVTVEDGPTKSDPRCLTRYYSSFINPERDLASGLIGPLLICYKESVDQRGNQM 585
Query: 908 FNPRRKLEFALLFLVFDENESWYLDDNIKTYSDHPEKVNKDDEEFIESNKMHAINGRMFG 967
+ +R + +LF +FDEN+SWY+ +N++ + + K D F SN MH+ING +F
Sbjct: 586 MSDKRNV---ILFSIFDENQSWYITENMQRFLPNAAKTQPQDPGFQASNIMHSINGYVFD 642
Query: 968 NLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRGVYSSDVFDIFPGTYQTLE 1027
+L+ LT+ + + W+++ +G + D ++ F G++F KH+ VY D +FP + +T+
Sbjct: 643 SLE-LTVCLHEVAYWHILSVGAQTDFLSIFFSGYTF--KHKMVY-EDTLTLFPFSGETVF 698
Query: 1028 MFPRTPGIWLLHCHVTDHIHAGM 1050
M PG+W+L CH +D GM
Sbjct: 699 MSMENPGLWVLGCHNSDFRKRGM 721
</PRE>
<PRE>
Score = 242 bits (618), Expect = 2e-63
Identities = 132/345 (38%), Positives = 189/345 (54%), Gaps = 18/345 (5%)
Query: 24 YYIGIIETTWDYA-----SDHGEKKLISVDTEHSNIYLQNGPDRIGRLYKKALYLQYTDE 78
+YI E WDYA SD+G K + YL NGP RIGR YKK ++ YTDE
Sbjct: 403 HYISAEEEDWDYAPSVPTSDNGSYK---------SQYLSNGPHRIGRKYKKVRFIAYTDE 453
Query: 79 TFRTTIEKPVWLGFLGPIIKAETGDKVYVHLKNLASRPYTFHSHGITYYKEHEGAIYPDN 138
TF+T G LGP++ E GD + + KN ASRPY + HGIT P
Sbjct: 454 TFKTRETIQHESGLLGPLLYGEVGDTLLIIFKNQASRPYNIYPHGITDVSPLHARRLPRG 513
Query: 139 TTDFQRADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASGLIGPLI 198
+ D ++PGE + Y T E P + D C+TR Y S I+ +D+ASGLIGPL+
Sbjct: 514 IKHVK--DLPIHPGEIFKYKWTVTVEDGPTKSDPRCLTRYYSSFINPERDLASGLIGPLL 571
Query: 199 ICKKDSLDKEKEKHI-DREFVVMFSVVDENFSWYLEDNIKTYCSEPEKVDKDNEDFQESN 257
IC K+S+D+ + + D+ V++FS+ DEN SWY+ +N++ + K + FQ SN
Sbjct: 572 ICYKESVDQRGNQMMSDKRNVILFSIFDENQSWYITENMQRFLPNAAKTQPQDPGFQASN 631
Query: 258 RMYSVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFHGQALTNKNYRIDTINLF 317
M+S+NGY F SL L++C + W++ +G + D + FF G +K DT+ LF
Sbjct: 632 IMHSINGYVFDSLE-LTVCLHEVAYWHILSVGAQTDFLSIFFSGYTFKHKMVYEDTLTLF 690
Query: 318 PATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQVQECNKSSS 362
P + +M +NPG W+L C N + K G+ A +V C+KS+S
Sbjct: 691 PFSGETVFMSMENPGLWVLGCHNSDFRKRGMTALLKVSSCDKSTS 735
</PRE>
<PRE>
Score = 235 bits (599), Expect = 4e-61
Identities = 122/343 (35%), Positives = 182/343 (52%), Gaps = 22/343 (6%)
Query: 726 TFYLGERTYYIAAVEVEWDYSPQREWEKELHHLQEQNVSNAFLDKGEFYIGSKYKKVVYR 785
+F R Y+IAAVE WDY + Q NV ++KKVV++
Sbjct: 1679 SFQQKTRHYFIAAVERLWDYGMSTSHVLR-NRYQSDNVP-------------QFKKVVFQ 1724
Query: 786 QYTDSTFRVPVERKAEEEHLGILGPQLHADVGDKVKIIFKNMATRPYSIHAHGV------ 839
++TD +F P+ R EHLG+LGP + A+V D + + FKN A+RPYS ++ +
Sbjct: 1725 EFTDGSFSQPLYRGELNEHLGLLGPYIRAEVEDNIMVTFKNQASRPYSFYSSLISYKEDQ 1784
Query: 840 QTESSTVTPTLPGETLTYVWKIPERSGAGTEDSACIPWAYYSTVDQVKDLYSGLIGPLIV 899
+ E P ET Y WK+ ++ C WAY+S VD +D++SGLIGPL++
Sbjct: 1785 RGEEPRRNFVKPNETKIYFWKVQHHMAPTEDEFDCKAWAYFSDVDLERDMHSGLIGPLLI 1844
Query: 900 CRRPYLKVFNPRRKL--EFALLFLVFDENESWYLDDNIKTYSDHPEKVNKDDEEFIESNK 957
C L + R+ EFALLF +FDE +SWY +N+K P +D E+ +
Sbjct: 1845 CHANTLNPAHGRQVSVQEFALLFTIFDETKSWYFTENVKRNCKTPCNFQMEDPTLKENYR 1904
Query: 958 MHAINGRMFGNLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRGVYSSDVFD 1017
HAING + L GL M + WYL+ MGN ++ ++HF GH F + + Y V++
Sbjct: 1905 FHAINGYVMDTLPGLVMAQDQRIRWYLLSMGNNENIQSIHFSGHVFTVRKKEEYKMAVYN 1964
Query: 1018 IFPGTYQTLEMFPRTPGIWLLHCHVTDHIHAGMETTYTVLQNE 1060
++PG ++TLEM P GIW + C + +H+ AGM T + V +
Sbjct: 1965 LYPGVFETLEMIPSRAGIWRVECLIGEHLQAGMSTLFLVYSKQ 2007
</PRE>
<PRE>
Score = 197 bits (502), Expect = 6e-50
Identities = 125/356 (35%), Positives = 178/356 (49%), Gaps = 39/356 (10%)
Query: 372 RHYYIAAEEIIWNYAPSGIDIFTKENLTAPGSDSAVFFEQGTTRIGGSYKKLVYREYTDA 431
RHY+IAA E +W+Y S + SD+ F KK+V++E+TD
Sbjct: 1685 RHYFIAAVERLWDYGMSTSHVLRNRYQ----SDNVPQF-----------KKVVFQEFTDG 1729
Query: 432 SFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGVRFNKNNEGTYY 491
SF+ RG EHLG+LGP I AEV D I VTF N+ + P S +Y
Sbjct: 1730 SFSQPLYRGELNEHLGLLGPYIRAEVEDNIMVTFKNQASRPYS---------------FY 1774
Query: 492 SP--NYNPQSRSVPPSASHVAPTETFTYEWTVPKEVGPTNADPVCLAKMYYSAVDPTKDI 549
S +Y R P + V P ET Y W V + PT + C A Y+S VD +D+
Sbjct: 1775 SSLISYKEDQRGEEPRRNFVKPNETKIYFWKVQHHMAPTEDEFDCKAWAYFSDVDLERDM 1834
Query: 550 FTGLIGPMKICKKGSLH-ANGRQKDVDKEFYLFPTVFDENESLLLEDNIRMFTTAPDQVD 608
+GLIGP+ IC +L+ A+GRQ V +EF L T+FDE +S +N++ P
Sbjct: 1835 HSGLIGPLLICHANTLNPAHGRQVSV-QEFALLFTIFDETKSWYFTENVKRNCKTPCNFQ 1893
Query: 609 KEDEDFQESNKMHSMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGIYFSGNTYLWR 668
ED +E+ + H++NG++ PGL M + + WYL S GN ++ I+FSG+ + R
Sbjct: 1894 MEDPTLKENYRFHAINGYVMDTLPGLVMAQDQRIRWYLLSMGNNENIQSIHFSGHVFTVR 1953
Query: 669 GE---RRDTANLFPQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTV--NQCR 719
+ + NL+P TL M P G + VECL +H GM + V QC+
Sbjct: 1954 KKEEYKMAVYNLYPGVFETLEMIPSRAGIWRVECLIGEHLQAGMSTLFLVYSKQCQ 2009
</PRE>
<PRE>
Score = 191 bits (485), Expect = 6e-48
Identities = 107/344 (31%), Positives = 170/344 (49%), Gaps = 32/344 (9%)
Query: 20 KEKHYYIGIIETTWDYASDHGEKKLISVDTEH--SNIYLQNGPDRIGRLYKKALYLQYTD 77
K +HY+I +E WDY + T H N Y + + +KK ++ ++TD
Sbjct: 1683 KTRHYFIAAVERLWDYG----------MSTSHVLRNRYQSDNVPQ----FKKVVFQEFTD 1728
Query: 78 ETFRTTI---EKPVWLGFLGPIIKAETGDKVYVHLKNLASRPYTFHSHGITYYKEHEGAI 134
+F + E LG LGP I+AE D + V KN ASRPY+F+S I+Y ++ G
Sbjct: 1729 GSFSQPLYRGELNEHLGLLGPYIRAEVEDNIMVTFKNQASRPYSFYSSLISYKEDQRGE- 1787
Query: 135 YPDNTTDFQRADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASGLI 194
+ + V P E Y +P E + +C Y S +D +D+ SGLI
Sbjct: 1788 --------EPRRNFVKPNETKIYFWKVQHHMAPTEDEFDCKAWAYFSDVDLERDMHSGLI 1839
Query: 195 GPLIICKKDSLDKEKEKHID-REFVVMFSVVDENFSWYLEDNIKTYCSEPEKVDKDNEDF 253
GPL+IC ++L+ + + +EF ++F++ DE SWY +N+K C P ++
Sbjct: 1840 GPLLICHANTLNPAHGRQVSVQEFALLFTIFDETKSWYFTENVKRNCKTPCNFQMEDPTL 1899
Query: 254 QESNRMYSVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFHGQALT---NKNYR 310
+E+ R +++NGY +LPGL M + R++WYL MGN ++ + F G T + Y+
Sbjct: 1900 KENYRFHAINGYVMDTLPGLVMAQDQRIRWYLLSMGNNENIQSIHFSGHVFTVRKKEEYK 1959
Query: 311 IDTINLFPATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQV 354
+ NL+P M+ G W + C HL+AG+ F V
Sbjct: 1960 MAVYNLYPGVFETLEMIPSRAGIWRVECLIGEHLQAGMSTLFLV 2003
</PRE>
<PRE>
Score = 172 bits (436), Expect = 3e-42
Identities = 113/337 (33%), Positives = 170/337 (49%), Gaps = 34/337 (10%)
Query: 732 RTYYIAAVEVEWDYSPQREWEKELHHLQE--QNVSNAFLDKGEFYIGSKYKKVVYRQYTD 789
R YY+ AVE+ W+Y Q + LH +S +F F YKK V+ +Y D
Sbjct: 22 RRYYLGAVELSWNYI-QSDLLSVLHTDSRFLPRMSTSF----PFNTSIMYKKTVFVEYKD 76
Query: 790 STFRVPVERKAEEEHLGILGPQLHADVGDKVKIIFKNMATRPYSIHAHGV---------- 839
F + K +G+LGP + +V D V I KNMA+ P S+HA GV
Sbjct: 77 QLFNIA---KPRPPWMGLLGPTIWTEVHDTVVITLKNMASHPVSLHAVGVSYWKASEGDE 133
Query: 840 -QTESSTVTP----TLPGETLTYVWKIPERSGAGTEDSACIPWAYYSTVDQVKDLYSGLI 894
+ ++S + PGE+ TYVW++ + +G D C+ ++Y S VD VKDL SGLI
Sbjct: 134 YEDQTSQMEKEDDKVFPGESHTYVWQVLKENGPMASDPPCLTYSYMSHVDLVKDLNSGLI 193
Query: 895 GPLIVCRRPYLKVFNPRRKLEFALLFLVFDENESWYLDDNIKTYSDHPEKVNKDDEEFIE 954
G L+VC+ L + +F LLF VFDE +SW+ + N +Y+ + + D
Sbjct: 194 GALLVCKEGSLSKERTQMLYQFVLLFAVFDEGKSWHSETN-DSYTQSMDSASARDWP--- 249
Query: 955 SNKMHAINGRMFGNLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRGVYSSD 1014
KMH +NG + +L GL V W+++GMG ++H++ GH+F ++ S
Sbjct: 250 --KMHTVNGYVNRSLPGLIGCHRKSVYWHVIGMGTTPEIHSIFLEGHTFFVRNHRQAS-- 305
Query: 1015 VFDIFPGTYQTLEMFPRTPGIWLLHCHVTDHIHAGME 1051
+I P T+ T + G +LL CH++ H H GME
Sbjct: 306 -LEISPITFLTAQTLLIDLGQFLLFCHISSHKHDGME 341
</PRE>
<PRE>
><a name = 2506228></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02506228&dopt=GenPept" >sp|P12263|FA8_PIG</a> Coagulation factor VIII precursor (Procoagulant component)
Length = 2133
Score = 416 bits (1068), Expect = e-115
Identities = 254/762 (33%), Positives = 392/762 (51%), Gaps = 69/762 (9%)
Query: 4 LILGIFLFLCSTP-AWAKEKHYYIGIIETTWDYASDHGEKKLISVDTEHSNIYLQNGPDR 62
L L +FLC P ++ + YY+G +E +WDY ++L VDT P
Sbjct: 3 LELSTCVFLCLLPLGFSAIRRYYLGAVELSWDYRQSELLREL-HVDTRFPATAPGALPLG 61
Query: 63 IGRLYKKALYLQYTDETFRTTIEKPVWLGFLGPIIKAETGDKVYVHLKNLASRPYTFHSH 122
LYKK +++++TD+ F +P W+G LGP I+AE D V V LKN+AS P + H+
Sbjct: 62 PSVLYKKTVFVEFTDQLFSVARPRPPWMGLLGPTIQAEVYDTVVVTLKNMASHPVSLHAV 121
Query: 123 GITYYKEHEGAIYPDNTTDFQRADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSH 182
G++++K EGA Y D+T+ ++ DDKV PG+ TY+ +E P D C+T Y SH
Sbjct: 122 GVSFWKSSEGAEYEDHTSQREKEDDKVLPGKSQTYVWQVLKENGPTASDPPCLTYSYLSH 181
Query: 183 IDAPKDIASGLIGPLIICKKDSLDKEKEKHIDREFVVMFSVVDENFSWYLEDNIK-TYCS 241
+D KD+ SGLIG L++C++ SL +E+ +++ EFV++F+V DE SW+ N T
Sbjct: 182 VDLVKDLNSGLIGALLVCREGSLTRERTQNL-HEFVLLFAVFDEGKSWHSARNDSWTRAM 240
Query: 242 EPEKVDKDNEDFQESNRMYSVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFHG 301
+P + M++VNGY SLPGL C + V W++ GMG +VH+ F G
Sbjct: 241 DPAPA-------RAQPAMHTVNGYVNRSLPGLIGCHKKSVYWHVIGMGTSPEVHSIFLEG 293
Query: 302 QALTNKNYRIDTINLFPATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQVQEC---- 357
+++R ++ + P T A + G+++L C +H G++A +V+ C
Sbjct: 294 HTFLVRHHRQASLEISPLTFLTAQTFLMDLGQFLLFCHISSHHHGGMEAHVRVESCAEEP 353
Query: 358 ---NKSSSKDN-------------------------IRGKHVRH-----YYIAAEEIIWN 384
K+ +++ IR +H +YI+AEE W+
Sbjct: 354 QLRRKADEEEDYDDNLYDSDMDVVRLDGDDVSPFIQIRSVAKKHPKTWVHYISAEEEDWD 413
Query: 385 YAPSGIDIFTKENLTAPGSDS--AVFFEQGTTRIGGSYKKLVYREYTDASFTNRKERGPE 442
YAP+ + +P S +++ G RIG YKK + YTD +F RK E
Sbjct: 414 YAPA---------VPSPSDRSYKSLYLNSGPQRIGRKYKKARFVAYTDVTFKTRKAIPYE 464
Query: 443 EEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGVRFNKNNEGTYYSPNYNPQSRSV 502
GILGP+++ EVGDT+ + F NK + P +I P G+ + + +
Sbjct: 465 S---GILGPLLYGEVGDTLLIIFKNKASRPYNIYPHGITDVSALHPGRLLKGWK-HLKDM 520
Query: 503 PPSASHVAPTETFTYEWTVPKEVGPTNADPVCLAKMYYSAVDPTKDIFTGLIGPMKICKK 562
P + P ETF Y+WTV E GPT +DP CL + Y S+++ KD+ +GLIGP+ IC K
Sbjct: 521 P-----ILPGETFKYKWTVTVEDGPTKSDPRCLTRYYSSSINLEKDLASGLIGPLLICYK 575
Query: 563 GSLHANGRQKDVDKEFYLFPTVFDENESLLLEDNIRMFTTAPDQVDKEDEDFQESNKMHS 622
S+ G Q DK + +VFDEN+S L +NI+ F PD + +D +FQ SN MHS
Sbjct: 576 ESVDQRGNQMMSDKRNVILFSVFDENQSWYLAENIQRFLPNPDGLQPQDPEFQASNIMHS 635
Query: 623 MNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGIYFSGNTYLWRGERRDTANLFPQTS 682
+NG+++ + L++C + WY+ S G + D ++FSG T+ + DT LFP +
Sbjct: 636 INGYVFDSLQ-LSVCLHEVAYWYILSVGAQTDFLSVFFSGYTFKHKMVYEDTLTLFPFSG 694
Query: 683 LTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTVNQCRRQSED 724
T+ M + G + + C +D GM V C R D
Sbjct: 695 ETVFMSMENPGLWVLGCHNSDLRNRGMTALLKVYSCDRDIGD 736
</PRE>
<PRE>
Score = 379 bits (972), Expect = e-104
Identities = 251/742 (33%), Positives = 379/742 (50%), Gaps = 103/742 (13%)
Query: 371 VRHYYIAAEEIIWNYAPSGI----DIFTKENLTAPGSDSAVFFEQGTTRIGGS--YKKLV 424
+R YY+ A E+ W+Y S + + T+ TAPG+ +G S YKK V
Sbjct: 21 IRRYYLGAVELSWDYRQSELLRELHVDTRFPATAPGA----------LPLGPSVLYKKTV 70
Query: 425 YREYTDASFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGVRFNK 484
+ E+TD F+ + R P +G+LGP I AEV DT+ VT N ++P+S+ +GV F K
Sbjct: 71 FVEFTDQLFSVARPRPP---WMGLLGPTIQAEVYDTVVVTLKNMASHPVSLHAVGVSFWK 127
Query: 485 NNEGTYYSPNYNPQSRSVPPSASHVAPTETFTYEWTVPKEVGPTNADPVCLAKMYYSAVD 544
++EG Y + + + + V P ++ TY W V KE GPT +DP CL Y S VD
Sbjct: 128 SSEGAEYEDHTSQREKE----DDKVLPGKSQTYVWQVLKENGPTASDPPCLTYSYLSHVD 183
Query: 545 PTKDIFTGLIGPMKICKKGSLHANGRQKDVDKEFYLFPTVFDENESLLLEDNIRMFTTAP 604
KD+ +GLIG + +C++GSL Q EF L VFDE +S N +T A
Sbjct: 184 LVKDLNSGLIGALLVCREGSLTRERTQNL--HEFVLLFAVFDEGKSWHSARN-DSWTRAM 240
Query: 605 DQVDKEDEDFQESNKMHSMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGIYFSGNT 664
D + MH++NG++ + PGL C SV W++ G +VH I+ G+T
Sbjct: 241 DPAPARAQP-----AMHTVNGYVNRSLPGLIGCHKKSVYWHVIGMGTSPEVHSIFLEGHT 295
Query: 665 YLWRGERRDTANLFPQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTVNQC------ 718
+L R R+ + + P T LT + G F + C + H+ GGM+ V C
Sbjct: 296 FLVRHHRQASLEISPLTFLTAQTFLMDLGQFLLFCHISSHHHGGMEAHVRVESCAEEPQL 355
Query: 719 RRQSE-----DSTFYLGER---------------------------TYYIAAVEVEWDYS 746
RR+++ D Y + +YI+A E +WDY+
Sbjct: 356 RRKADEEEDYDDNLYDSDMDVVRLDGDDVSPFIQIRSVAKKHPKTWVHYISAEEEDWDYA 415
Query: 747 PQREWEKELHHLQEQNVSNAFLDKGEFYIGSKYKKVVYRQYTDSTFRVPVERKAEEEHLG 806
P + +++ + +L+ G IG KYKK + YTD TF+ RKA G
Sbjct: 416 PA------VPSPSDRSYKSLYLNSGPQRIGRKYKKARFVAYTDVTFKT---RKAIPYESG 466
Query: 807 ILGPQLHADVGDKVKIIFKNMATRPYSIHAHGVQTESSTVT-------------PTLPGE 853
ILGP L+ +VGD + IIFKN A+RPY+I+ HG+ S+ P LPGE
Sbjct: 467 ILGPLLYGEVGDTLLIIFKNKASRPYNIYPHGITDVSALHPGRLLKGWKHLKDMPILPGE 526
Query: 854 TLTYVWKIPERSGAGTEDSACIPWAYYSTVDQVKDLYSGLIGPLIVCRRPYL-----KVF 908
T Y W + G D C+ Y S+++ KDL SGLIGPL++C + + ++
Sbjct: 527 TFKYKWTVTVEDGPTKSDPRCLTRYYSSSINLEKDLASGLIGPLLICYKESVDQRGNQMM 586
Query: 909 NPRRKLEFALLFLVFDENESWYLDDNIKTYSDHPEKVNKDDEEFIESNKMHAINGRMFGN 968
+ +R + +LF VFDEN+SWYL +NI+ + +P+ + D EF SN MH+ING +F +
Sbjct: 587 SDKRNV---ILFSVFDENQSWYLAENIQRFLPNPDGLQPQDPEFQASNIMHSINGYVFDS 643
Query: 969 LQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRGVYSSDVFDIFPGTYQTLEM 1028
LQ L++ + + WY++ +G + D +V F G++F KH+ VY D +FP + +T+ M
Sbjct: 644 LQ-LSVCLHEVAYWYILSVGAQTDFLSVFFSGYTF--KHKMVY-EDTLTLFPFSGETVFM 699
Query: 1029 FPRTPGIWLLHCHVTDHIHAGM 1050
PG+W+L CH +D + GM
Sbjct: 700 SMENPGLWVLGCHNSDLRNRGM 721
</PRE>
<PRE>
Score = 247 bits (630), Expect = 9e-65
Identities = 132/339 (38%), Positives = 189/339 (54%), Gaps = 12/339 (3%)
Query: 24 YYIGIIETTWDYASDHGEKKLISVDTEHSNIYLQNGPDRIGRLYKKALYLQYTDETFRTT 83
+YI E WDYA D + ++YL +GP RIGR YKKA ++ YTD TF+T
Sbjct: 403 HYISAEEEDWDYAPAVPSPS----DRSYKSLYLNSGPQRIGRKYKKARFVAYTDVTFKTR 458
Query: 84 IEKPVWLGFLGPIIKAETGDKVYVHLKNLASRPYTFHSHGITYYKEHEGAIYPDNTTDFQ 143
P G LGP++ E GD + + KN ASRPY + HGIT A++P
Sbjct: 459 KAIPYESGILGPLLYGEVGDTLLIIFKNKASRPYNIYPHGIT----DVSALHPGRLLKGW 514
Query: 144 R--ADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASGLIGPLIICK 201
+ D + PGE + Y T E P + D C+TR Y S I+ KD+ASGLIGPL+IC
Sbjct: 515 KHLKDMPILPGETFKYKWTVTVEDGPTKSDPRCLTRYYSSSINLEKDLASGLIGPLLICY 574
Query: 202 KDSLDKEKEKHI-DREFVVMFSVVDENFSWYLEDNIKTYCSEPEKVDKDNEDFQESNRMY 260
K+S+D+ + + D+ V++FSV DEN SWYL +NI+ + P+ + + +FQ SN M+
Sbjct: 575 KESVDQRGNQMMSDKRNVILFSVFDENQSWYLAENIQRFLPNPDGLQPQDPEFQASNIMH 634
Query: 261 SVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFHGQALTNKNYRIDTINLFPAT 320
S+NGY F SL LS+C + WY+ +G + D + FF G +K DT+ LFP +
Sbjct: 635 SINGYVFDSLQ-LSVCLHEVAYWYILSVGAQTDFLSVFFSGYTFKHKMVYEDTLTLFPFS 693
Query: 321 LFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQVQECNK 359
+M +NPG W+L C N + G+ A +V C++
Sbjct: 694 GETVFMSMENPGLWVLGCHNSDLRNRGMTALLKVYSCDR 732
</PRE>
<PRE>
Score = 240 bits (612), Expect = 1e-62
Identities = 123/347 (35%), Positives = 184/347 (52%), Gaps = 28/347 (8%)
Query: 726 TFYLGERTYYIAAVEVEWDYSPQREWEKELHHLQEQNVSNAFLDKGEFYIGSKYKKVVYR 785
+F R Y+IAAVE WDY + Q V ++KKVV+R
Sbjct: 1491 SFQKRTRHYFIAAVEQLWDYGMSESPRALRNRAQNGEVP-------------RFKKVVFR 1537
Query: 786 QYTDSTFRVPVERKAEEEHLGILGPQLHADVGDKVKIIFKNMATRPYSIHA--------- 836
++ D +F P R +HLG+LGP + A+V D + + FKN A+RPYS ++
Sbjct: 1538 EFADGSFTQPSYRGELNKHLGLLGPYIRAEVEDNIMVTFKNQASRPYSFYSSLISYPDDQ 1597
Query: 837 -HGVQTESSTVTPTLPGETLTYVWKIPERSGAGTEDSACIPWAYYSTVDQVKDLYSGLIG 895
G + + V P ET TY WK+ ++ C WAY+S VD KD++SGLIG
Sbjct: 1598 EQGAEPRHNFVQPN---ETRTYFWKVQHHMAPTEDEFDCKAWAYFSDVDLEKDVHSGLIG 1654
Query: 896 PLIVCRRPYLKVFNPRRKL--EFALLFLVFDENESWYLDDNIKTYSDHPEKVNKDDEEFI 953
PL++CR L + R+ EFAL F +FDE +SWY +N++ P + +D
Sbjct: 1655 PLLICRANTLNAAHGRQVTVQEFALFFTIFDETKSWYFTENVERNCRAPCHLQMEDPTLK 1714
Query: 954 ESNKMHAINGRMFGNLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRGVYSS 1013
E+ + HAING + L GL M + WYL+ MG+ ++H++HF GH F + + Y
Sbjct: 1715 ENYRFHAINGYVMDTLPGLVMAQNQRIRWYLLSMGSNENIHSIHFSGHVFSVRKKEEYKM 1774
Query: 1014 DVFDIFPGTYQTLEMFPRTPGIWLLHCHVTDHIHAGMETTYTVLQNE 1060
V++++PG ++T+EM P GIW + C + +H+ AGM TT+ V E
Sbjct: 1775 AVYNLYPGVFETVEMLPSKVGIWRIECLIGEHLQAGMSTTFLVYSKE 1821
</PRE>
<PRE>
Score = 203 bits (516), Expect = 2e-51
Identities = 122/351 (34%), Positives = 179/351 (50%), Gaps = 31/351 (8%)
Query: 369 KHVRHYYIAAEEIIWNYAPSGIDIFTKENLTAPGSDSAVFFEQGTTRIGGSYKKLVYREY 428
K RHY+IAA E +W+Y S + L + V +KK+V+RE+
Sbjct: 1494 KRTRHYFIAAVEQLWDYGMSE----SPRALRNRAQNGEV----------PRFKKVVFREF 1539
Query: 429 TDASFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGVRFNKNNEG 488
D SFT RG +HLG+LGP I AEV D I VTF N+ + P S + +
Sbjct: 1540 ADGSFTQPSYRGELNKHLGLLGPYIRAEVEDNIMVTFKNQASRPYSFYSSLISYP----- 1594
Query: 489 TYYSPNYNPQSRSVPPSASHVAPTETFTYEWTVPKEVGPTNADPVCLAKMYYSAVDPTKD 548
+ Q + P + V P ET TY W V + PT + C A Y+S VD KD
Sbjct: 1595 -------DDQEQGAEPRHNFVQPNETRTYFWKVQHHMAPTEDEFDCKAWAYFSDVDLEKD 1647
Query: 549 IFTGLIGPMKICKKGSLH-ANGRQKDVDKEFYLFPTVFDENESLLLEDNIRMFTTAPDQV 607
+ +GLIGP+ IC+ +L+ A+GRQ V +EF LF T+FDE +S +N+ AP +
Sbjct: 1648 VHSGLIGPLLICRANTLNAAHGRQVTV-QEFALFFTIFDETKSWYFTENVERNCRAPCHL 1706
Query: 608 DKEDEDFQESNKMHSMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGIYFSGNTYLW 667
ED +E+ + H++NG++ PGL M + + WYL S G+ ++H I+FSG+ +
Sbjct: 1707 QMEDPTLKENYRFHAINGYVMDTLPGLVMAQNQRIRWYLLSMGSNENIHSIHFSGHVFSV 1766
Query: 668 RGE---RRDTANLFPQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTV 715
R + + NL+P T+ M P G + +ECL +H GM + V
Sbjct: 1767 RKKEEYKMAVYNLYPGVFETVEMLPSKVGIWRIECLIGEHLQAGMSTTFLV 1817
</PRE>
<PRE>
Score = 192 bits (488), Expect = 3e-48
Identities = 115/377 (30%), Positives = 183/377 (48%), Gaps = 31/377 (8%)
Query: 20 KEKHYYIGIIETTWDYASDHGEKKLISVDTEHSNIYLQNGPDRIGRLYKKALYLQYTDET 79
+ +HY+I +E WDY + L + QNG + R +KK ++ ++ D +
Sbjct: 1495 RTRHYFIAAVEQLWDYGMSESPRALRN--------RAQNG--EVPR-FKKVVFREFADGS 1543
Query: 80 FRTTI---EKPVWLGFLGPIIKAETGDKVYVHLKNLASRPYTFHSHGITYYKEHEGAIYP 136
F E LG LGP I+AE D + V KN ASRPY+F+S I+Y + E P
Sbjct: 1544 FTQPSYRGELNKHLGLLGPYIRAEVEDNIMVTFKNQASRPYSFYSSLISYPDDQEQGAEP 1603
Query: 137 DNTTDFQRADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASGLIGP 196
+ V P E TY +P E + +C Y S +D KD+ SGLIGP
Sbjct: 1604 RHNF--------VQPNETRTYFWKVQHHMAPTEDEFDCKAWAYFSDVDLEKDVHSGLIGP 1655
Query: 197 LIICKKDSLDKEKEKHID-REFVVMFSVVDENFSWYLEDNIKTYCSEPEKVDKDNEDFQE 255
L+IC+ ++L+ + + +EF + F++ DE SWY +N++ C P + ++ +E
Sbjct: 1656 LLICRANTLNAAHGRQVTVQEFALFFTIFDETKSWYFTENVERNCRAPCHLQMEDPTLKE 1715
Query: 256 SNRMYSVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFHGQALT---NKNYRID 312
+ R +++NGY +LPGL M R++WYL MG+ ++H+ F G + + Y++
Sbjct: 1716 NYRFHAINGYVMDTLPGLVMAQNQRIRWYLLSMGSNENIHSIHFSGHVFSVRKKEEYKMA 1775
Query: 313 TINLFPATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQV--QECNKSSSKDNIRGKH 370
NL+P M+ G W + C HL+AG+ F V +EC + R
Sbjct: 1776 VYNLYPGVFETVEMLPSKVGIWRIECLIGEHLQAGMSTTFLVYSKECQAPLGMASGR--- 1832
Query: 371 VRHYYIAAEEIIWNYAP 387
+R + I A +AP
Sbjct: 1833 IRDFQITASGQYGQWAP 1849
</PRE>
<PRE>
Score = 180 bits (456), Expect = 1e-44
Identities = 120/342 (35%), Positives = 168/342 (49%), Gaps = 44/342 (12%)
Query: 732 RTYYIAAVEVEWDYSPQREWEKELHHLQEQNVSNAF--LDKGEFYIGSK--YKKVVYRQY 787
R YY+ AVE+ WDY Q E +ELH V F G +G YKK V+ ++
Sbjct: 22 RRYYLGAVELSWDYR-QSELLRELH------VDTRFPATAPGALPLGPSVLYKKTVFVEF 74
Query: 788 TDSTFRVPVERKAEEEHLGILGPQLHADVGDKVKIIFKNMATRPYSIHAHGVQTESSTV- 846
TD F V R +G+LGP + A+V D V + KNMA+ P S+HA GV S+
Sbjct: 75 TDQLFSVARPRPP---WMGLLGPTIQAEVYDTVVVTLKNMASHPVSLHAVGVSFWKSSEG 131
Query: 847 --------------TPTLPGETLTYVWKIPERSGAGTEDSACIPWAYYSTVDQVKDLYSG 892
LPG++ TYVW++ + +G D C+ ++Y S VD VKDL SG
Sbjct: 132 AEYEDHTSQREKEDDKVLPGKSQTYVWQVLKENGPTASDPPCLTYSYLSHVDLVKDLNSG 191
Query: 893 LIGPLIVCRRPYLKVFNPRRKLEFALLFLVFDENESWYL---DDNIKTYSDHPEKVNKDD 949
LIG L+VCR L + EF LLF VFDE +SW+ D + P +
Sbjct: 192 LIGALLVCREGSLTRERTQNLHEFVLLFAVFDEGKSWHSARNDSWTRAMDPAPARAQP-- 249
Query: 950 EEFIESNKMHAINGRMFGNLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRG 1009
MH +NG + +L GL V W+++GMG ++H++ GH+F +H
Sbjct: 250 -------AMHTVNGYVNRSLPGLIGCHKKSVYWHVIGMGTSPEVHSIFLEGHTFLVRHHR 302
Query: 1010 VYSSDVFDIFPGTYQTLEMFPRTPGIWLLHCHVTDHIHAGME 1051
S +I P T+ T + F G +LL CH++ H H GME
Sbjct: 303 QAS---LEISPLTFLTAQTFLMDLGQFLLFCHISSHHHGGME 341
</PRE>
<PRE>
><a name = 2493324></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02493324&dopt=GenPept" >sp|Q28107|FA5_BOVIN</a> Coagulation factor V precursor (Activated protein C cofactor)
Length = 2211
Score = 405 bits (1042), Expect = e-112
Identities = 241/722 (33%), Positives = 379/722 (52%), Gaps = 66/722 (9%)
Query: 19 AKEKHYYIGIIETTWDYASDHGEKKLISVDTEHSNIYLQNGPDRIGRLYKKALYLQYTDE 78
AK + +Y+ W+Y + + +L + P +KK +Y +Y +
Sbjct: 29 AKLRQFYVAAQSIRWNYRPE--------------STHLSSKPFETS--FKKIVYREY-EA 71
Query: 79 TFRTTIEKPVWLGFLGPIIKAETGDKVYVHLKNLASRPYTFHSHGITYYKEHEGAIYPDN 138
F+ + G LGP + AE GD + VH KN A +P + H+ GI Y K EGA Y D+
Sbjct: 72 YFQKEKPQSRTSGLLGPTLYAEVGDIMKVHFKNKAHKPLSIHAQGIKYSKFSEGASYSDH 131
Query: 139 TTDFQRADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASGLIGPLI 198
T ++ DD V PG++YTY + +E P D C+T IY+S+++ +D SGLIGPL+
Sbjct: 132 TLPMEKMDDAVAPGQEYTYEWIISEHSGPTHDDPPCLTHIYYSYVNLVEDFNSGLIGPLL 191
Query: 199 ICKKDSLDKE-KEKHIDREFVVMFSVVDENFSWYLEDNIKTYCSEPEKVDKDNEDFQESN 257
ICKK +L ++ +K +++ V+MF+V DE+ SW Q S+
Sbjct: 192 ICKKGTLTEDGTQKMFEKQHVLMFAVFDESKSWN----------------------QTSS 229
Query: 258 RMYSVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFHGQALTNKNYRIDTINLF 317
MY+VNGY G++P +++CA D + W+L GM + ++ + F+GQ L +++I I L
Sbjct: 230 LMYTVNGYVNGTMPDITVCAHDHISWHLIGMSSGPELFSIHFNGQVLEQNHHKISAITLV 289
Query: 318 PATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQVQECNKSS------SKDNIRGKHV 371
AT A M G W ++ H +AG+QA+ ++ C K + ++D R
Sbjct: 290 SATSTTANMTVSPEGRWTIASLIPRHFQAGMQAYIDIKNCAKKTRNPKKLTRDQRRHIKR 349
Query: 372 RHYYIAAEEIIWNYAPSGIDIFTKENLTAPGSDSAVFFEQGTTRIGGSYKKLVYREYTDA 431
Y+IAAEE+IW+YAP N+ ++ + + RIG YKK+VY++Y D
Sbjct: 350 WEYFIAAEEVIWDYAP-----IIPANMDK--KYRSLHLDNFSNRIGKHYKKVVYKQYQDD 402
Query: 432 SFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGVRFNKNNEGTYY 491
SFT R E P E GILGP+I A+V DT+++ F N + SI P GV F+ Y
Sbjct: 403 SFTKRLE-DPSSEGDGILGPIIRAQVRDTLKIVFKNMASRSYSIYPHGVTFSP------Y 455
Query: 492 SPNYNPQSRSVPPSASH-VAPTETFTYEWTVPKEVGPTNADPVCLAKMYYSAVDPTKDIF 550
N S S + V P ET+TY+W + + PT D CL + YYS VD T+D+
Sbjct: 456 DNEVNSSSTSGSNTMIRAVRPGETYTYKWNILESDEPTENDAQCLTRPYYSNVDITRDLA 515
Query: 551 TGLIGPMKICKKGSLHANGRQKDVDKEFYLFPTVFDENESLLLEDNIRMFTTAPDQVDKE 610
+GLIG + ICK SL G Q+ D E VFDEN+S +EDNI F P++V ++
Sbjct: 516 SGLIGLLLICKSRSLDRRGIQRAADIEQQAVFAVFDENKSWYIEDNIYKFCENPEKVKRD 575
Query: 611 DEDFQESNKMH-----SMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGIYFSGNTY 665
D F ESN M ++NG++ + P L C D+V W+ S G + D+ I+F+G+++
Sbjct: 576 DPKFYESNIMSNFTLPAINGYVPESIPILGFCFDDTVQWHFCSVGTQNDILTIHFTGHSF 635
Query: 666 LWRGERRDTANLFPQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTVNQCRRQSEDS 725
++ DT LFP ++ + D GT+ + + ++ + ++ ++ +C R +D
Sbjct: 636 IYGKRHEDTLTLFPMQGESVTVTMDNVGTWMLTTMNSNPRSKKLRLRFRDAKCIRNDDDD 695
Query: 726 TF 727
++
Sbjct: 696 SY 697
</PRE>
<PRE>
Score = 392 bits (1008), Expect = e-108
Identities = 245/698 (35%), Positives = 355/698 (50%), Gaps = 91/698 (13%)
Query: 371 VRHYYIAAEEIIWNYAPSGIDIFTKENLTAPGSDSAVFFEQGTTRIGGSYKKLVYREYTD 430
+R +Y+AA+ I WNY P + +K T S+KK+VYREY +
Sbjct: 31 LRQFYVAAQSIRWNYRPESTHLSSKPFET-------------------SFKKIVYREY-E 70
Query: 431 ASFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGVRFNKNNEGTY 490
A F K P+ G+LGP ++AEVGD ++V F NK PLSI G++++K +EG
Sbjct: 71 AYFQKEK---PQSRTSGLLGPTLYAEVGDIMKVHFKNKAHKPLSIHAQGIKYSKFSEGAS 127
Query: 491 YSPNYNPQSRSVPPSASHVAPTETFTYEWTVPKEVGPTNADPVCLAKMYYSAVDPTKDIF 550
YS + P + VAP + +TYEW + + GPT+ DP CL +YYS V+ +D
Sbjct: 128 YSDHTLPMEKM----DDAVAPGQEYTYEWIISEHSGPTHDDPPCLTHIYYSYVNLVEDFN 183
Query: 551 TGLIGPMKICKKGSLHANGRQKDVDKEFYLFPTVFDENESLLLEDNIRMFTTAPDQVDKE 610
+GLIGP+ ICKKG+L +G QK +K+ L VFDE++S
Sbjct: 184 SGLIGPLLICKKGTLTEDGTQKMFEKQHVLMFAVFDESKSWN------------------ 225
Query: 611 DEDFQESNKMHSMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGIYFSGNTYLWRGE 670
Q S+ M+++NG++ G P +T+C D + W+L + ++ I+F+G
Sbjct: 226 ----QTSSLMYTVNGYVNGTMPDITVCAHDHISWHLIGMSSGPELFSIHFNGQVLEQNHH 281
Query: 671 RRDTANLFPQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTVNQCRRQSE------- 723
+ L TS T +M EG + + L H+ GM+ + C +++
Sbjct: 282 KISAITLVSATSTTANMTVSPEGRWTIASLIPRHFQAGMQAYIDIKNCAKKTRNPKKLTR 341
Query: 724 DSTFYLGERTYYIAAVEVEWDYSP--QREWEKELHHLQEQNVSNAFLDKGEFYIGSKYKK 781
D ++ Y+IAA EV WDY+P +K+ L N SN IG YKK
Sbjct: 342 DQRRHIKRWEYFIAAEEVIWDYAPIIPANMDKKYRSLHLDNFSNR--------IGKHYKK 393
Query: 782 VVYRQYTDSTFRVPVERKAEEEHLGILGPQLHADVGDKVKIIFKNMATRPYSIHAHGVQ- 840
VVY+QY D +F +E + E GILGP + A V D +KI+FKNMA+R YSI+ HGV
Sbjct: 394 VVYKQYQDDSFTKRLEDPSSEGD-GILGPIIRAQVRDTLKIVFKNMASRSYSIYPHGVTF 452
Query: 841 -------TESST------VTPTLPGETLTYVWKIPERSGAGTEDSACIPWAYYSTVDQVK 887
SST + PGET TY W I E D+ C+ YYS VD +
Sbjct: 453 SPYDNEVNSSSTSGSNTMIRAVRPGETYTYKWNILESDEPTENDAQCLTRPYYSNVDITR 512
Query: 888 DLYSGLIGPLIVCRRPYLKVFNPRRK--LEFALLFLVFDENESWYLDDNIKTYSDHPEKV 945
DL SGLIG L++C+ L +R +E +F VFDEN+SWY++DNI + ++PEKV
Sbjct: 513 DLASGLIGLLLICKSRSLDRRGIQRAADIEQQAVFAVFDENKSWYIEDNIYKFCENPEKV 572
Query: 946 NKDDEEFIESNKMH-----AINGRMFGNLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHG 1000
+DD +F ESN M AING + ++ L D V W+ +G + D+ T+HF G
Sbjct: 573 KRDDPKFYESNIMSNFTLPAINGYVPESIPILGFCFDDTVQWHFCSVGTQNDILTIHFTG 632
Query: 1001 HSFQYKHRGVYSSDVFDIFPGTYQTLEMFPRTPGIWLL 1038
HSF Y G D +FP +++ + G W+L
Sbjct: 633 HSFIY---GKRHEDTLTLFPMQGESVTVTMDNVGTWML 667
</PRE>
<PRE>
Score = 234 bits (598), Expect = 5e-61
Identities = 139/368 (37%), Positives = 195/368 (52%), Gaps = 45/368 (12%)
Query: 715 VNQCRRQSEDSTFYLGERT-----YYIAAVEVEWDYSPQREWEKELHHLQEQNVSNAFLD 769
+N R + +YL T YYIAA E+ WDYS + + ++ ++ E V
Sbjct: 1549 INSSRNPDNIAAWYLRSNTGNRKYYYIAAEEISWDYSKFVQSD-DVDYVPEDTV------ 1601
Query: 770 KGEFYIGSKYKKVVYRQYTDSTFRVPVERKAEEEHLGILGPQLHADVGDKVKIIFKNMAT 829
YKKVV+R+Y DSTF + EEHLGILGP + A+V D +++ FKN+A+
Sbjct: 1602 ---------YKKVVFRKYLDSTFTKLDPQGEYEEHLGILGPVIRAEVDDVIQVRFKNLAS 1652
Query: 830 RPYSIHAHGVQTESSTVTPTL---------------PGETLTYVWKIPERSGAGTEDSAC 874
RPYS+HAHG+ E S+ T P +T TYVW RSG SAC
Sbjct: 1653 RPYSLHAHGLSYEKSSEGKTYEDDSPEWFKEDNAIQPNKTYTYVWHATTRSGPENPGSAC 1712
Query: 875 IPWAYYSTVDQVKDLYSGLIGPLIVCRRPYL--KVFNPRRKLEFALLFLVFDENESWYLD 932
WAYYS V+ KD++SGLIGPL++CR+ L + P EF LLF+VFDE +SWY D
Sbjct: 1713 RAWAYYSAVNPEKDIHSGLIGPLLICRKGTLDKETNMPVDMREFVLLFMVFDEKKSWYYD 1772
Query: 933 DNIKTYSDHPEKVNKDDEEFIESNKMHAINGRMFGNLQGLTMHVGDEVNWYLMGMGNEID 992
+ E S++ HAING ++ NL GL M+ + V +L+ +G D
Sbjct: 1773 ------KKPTRSWRRASSEVKNSHEFHAINGMIY-NLPGLRMYEQEWVRLHLLNLGGSRD 1825
Query: 993 LHTVHFHGHSFQYKHRGVYSSDVFDIFPGTYQTLEMFPRTPGIWLLHCHVTDHIHAGMET 1052
+H VHFHG + + V+ + PG+++TLEM PG WLL V + AGM+T
Sbjct: 1826 IHVVHFHGQTLLENGTQQHQLGVWPLLPGSFKTLEMKASKPGWWLLDTEVGEIQRAGMQT 1885
Query: 1053 TYTVLQNE 1060
+ ++ E
Sbjct: 1886 PFLIVDRE 1893
</PRE>
<PRE>
Score = 200 bits (509), Expect = 1e-50
Identities = 120/346 (34%), Positives = 187/346 (53%), Gaps = 32/346 (9%)
Query: 22 KHYYIGIIETTWDYASDHGEKKLISVDTEHSNIYLQNGPDRIGRLYKKALYLQYTDETFR 81
K+YYI E +WDY+ K + S D ++ P+ +YKK ++ +Y D TF
Sbjct: 1571 KYYYIAAEEISWDYS-----KFVQSDDVDYV-------PE--DTVYKKVVFRKYLDSTFT 1616
Query: 82 TTIEKPVW---LGFLGPIIKAETGDKVYVHLKNLASRPYTFHSHGITYYKEHEGAIYPDN 138
+ + LG LGP+I+AE D + V KNLASRPY+ H+HG++Y K EG Y D+
Sbjct: 1617 KLDPQGEYEEHLGILGPVIRAEVDDVIQVRFKNLASRPYSLHAHGLSYEKSSEGKTYEDD 1676
Query: 139 TTDFQRADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASGLIGPLI 198
+ ++ + D+ + P + YTY+ AT P C Y+S ++ KDI SGLIGPL+
Sbjct: 1677 SPEWFKEDNAIQPNKTYTYVWHATTRSGPENPGSACRAWAYYSAVNPEKDIHSGLIGPLL 1736
Query: 199 ICKKDSLDKEKEKHID-REFVVMFSVVDENFSWYLEDNIKTYCSEPEKV-DKDNEDFQES 256
IC+K +LDKE +D REFV++F V DE SWY Y +P + + + + + S
Sbjct: 1737 ICRKGTLDKETNMPVDMREFVLLFMVFDEKKSWY-------YDKKPTRSWRRASSEVKNS 1789
Query: 257 NRMYSVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFHGQALT---NKNYRIDT 313
+ +++NG + +LPGL M ++ V+ +L +G D+H FHGQ L + +++
Sbjct: 1790 HEFHAINGMIY-NLPGLRMYEQEWVRLHLLNLGGSRDIHVVHFHGQTLLENGTQQHQLGV 1848
Query: 314 INLFPATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQV--QEC 357
L P + M A PG W+L + +AG+Q F + +EC
Sbjct: 1849 WPLLPGSFKTLEMKASKPGWWLLDTEVGEIQRAGMQTPFLIVDREC 1894
</PRE>
<PRE>
Score = 191 bits (486), Expect = 5e-48
Identities = 140/429 (32%), Positives = 210/429 (48%), Gaps = 56/429 (13%)
Query: 356 ECNKSSSKDNIRGKHVR-------HYYIAAEEIIWNYAPSGIDIFTKENLTAPGSDSAVF 408
+ N S + DNI ++R +YYIAAEEI W+Y+ F + SD +
Sbjct: 1548 DINSSRNPDNIAAWYLRSNTGNRKYYYIAAEEISWDYSK-----FVQ-------SDDVDY 1595
Query: 409 FEQGTTRIGGSYKKLVYREYTDASFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNK 468
+ T YKK+V+R+Y D++FT +G EEHLGILGPVI AEV D I+V F N
Sbjct: 1596 VPEDTV-----YKKVVFRKYLDSTFTKLDPQGEYEEHLGILGPVIRAEVDDVIQVRFKNL 1650
Query: 469 GAYPLSIEPIGVRFNKNNEGTYY---SPNYNPQSRSVPPSASHVAPTETFTYEWTVPKEV 525
+ P S+ G+ + K++EG Y SP + + ++ P+ +T+TY W
Sbjct: 1651 ASRPYSLHAHGLSYEKSSEGKTYEDDSPEWFKEDNAIQPN-------KTYTYVWHATTRS 1703
Query: 526 GPTNADPVCLAKMYYSAVDPTKDIFTGLIGPMKICKKGSLHANGRQKDVDKEFYLFPTVF 585
GP N C A YYSAV+P KDI +GLIGP+ IC+KG+L +EF L VF
Sbjct: 1704 GPENPGSACRAWAYYSAVNPEKDIHSGLIGPLLICRKGTLDKETNMPVDMREFVLLFMVF 1763
Query: 586 DENESLLLEDN-IRMFTTAPDQVDKEDEDFQESNKMHSMNGFMYGNQPGLTMCKGDSVVW 644
DE +S + R + A +V + S++ H++NG +Y N PGL M + + V
Sbjct: 1764 DEKKSWYYDKKPTRSWRRASSEV-------KNSHEFHAINGMIY-NLPGLRMYEQEWVRL 1815
Query: 645 YLFSAGNEADVHGIYFSGNTYLWRGERRDTAN---LFPQTSLTLHMWPDTEGTFNVECLT 701
+L + G D+H ++F G T L G ++ L P + TL M G + ++
Sbjct: 1816 HLLNLGGSRDIHVVHFHGQTLLENGTQQHQLGVWPLLPGSFKTLEMKASKPGWWLLDTEV 1875
Query: 702 TDHYTGGMKQKYTV--NQCRRQSEDSTFYLGERTYYIAAVEVEWDYSPQREWEKELHHLQ 759
+ GM+ + + +C+ ST + + I A E W Y WE +L L
Sbjct: 1876 GEIQRAGMQTPFLIVDRECKMPMGLSTGLIADS--QIQASEF-WGY-----WEPKLARLN 1927
Query: 760 EQNVSNAFL 768
NA++
Sbjct: 1928 NGGSYNAWI 1936
</PRE>
<PRE>
Score = 155 bits (393), Expect = 3e-37
Identities = 101/337 (29%), Positives = 159/337 (46%), Gaps = 64/337 (18%)
Query: 732 RTYYIAAVEVEWDYSPQREWEKELHHLQEQNVSNAFLDKGEFYIGSKYKKVVYRQYTDST 791
R +Y+AA + W+Y P E HL + +F KK+VYR+Y ++
Sbjct: 32 RQFYVAAQSIRWNYRP------ESTHLSSKPFETSF------------KKIVYREY-EAY 72
Query: 792 FRVPVERKAEEEHLGILGPQLHADVGDKVKIIFKNMATRPYSIHAHGVQ--------TES 843
F+ + K + G+LGP L+A+VGD +K+ FKN A +P SIHA G++ + S
Sbjct: 73 FQ---KEKPQSRTSGLLGPTLYAEVGDIMKVHFKNKAHKPLSIHAQGIKYSKFSEGASYS 129
Query: 844 STVTP-------TLPGETLTYVWKIPERSGAGTEDSACIPWAYYSTVDQVKDLYSGLIGP 896
P PG+ TY W I E SG +D C+ YYS V+ V+D SGLIGP
Sbjct: 130 DHTLPMEKMDDAVAPGQEYTYEWIISEHSGPTHDDPPCLTHIYYSYVNLVEDFNSGLIGP 189
Query: 897 LIVCRRPYLKVFNPRRKLE--FALLFLVFDENESWYLDDNIKTYSDHPEKVNKDDEEFIE 954
L++C++ L ++ E L+F VFDE++SW
Sbjct: 190 LLICKKGTLTEDGTQKMFEKQHVLMFAVFDESKSWNQ----------------------T 227
Query: 955 SNKMHAINGRMFGNLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRGVYSSD 1014
S+ M+ +NG + G + +T+ D ++W+L+GM + +L ++HF+G + H +
Sbjct: 228 SSLMYTVNGYVNGTMPDITVCAHDHISWHLIGMSSGPELFSIHFNGQVLEQNHHKI---S 284
Query: 1015 VFDIFPGTYQTLEMFPRTPGIWLLHCHVTDHIHAGME 1051
+ T T M G W + + H AGM+
Sbjct: 285 AITLVSATSTTANMTVSPEGRWTIASLIPRHFQAGMQ 321
</PRE>
<PRE>
><a name = 18202922></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=18202922&dopt=GenPept" >sp|Q9GLP1|FA5_PIG</a> Coagulation factor V precursor (Activated protein C cofactor)
Length = 2258
Score = 402 bits (1032), Expect = e-111
Identities = 232/669 (34%), Positives = 363/669 (53%), Gaps = 45/669 (6%)
Query: 67 YKKALYLQYTDETFRTTIEKPVWLGFLGPIIKAETGDKVYVHLKNLASRPYTFHSHGITY 126
+KK +Y +Y + F+ G LGP + A+ GD + VH +N A +P + H GI Y
Sbjct: 61 FKKIVYREY-EAYFQKEKPPSRMSGLLGPTLYADVGDIMKVHFRNKADKPLSIHPQGIKY 119
Query: 127 YKEHEGAIYPDNTTDFQRADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAP 186
K EGA YPD+T ++ DD V PG++YTY +E+ P D C+T IY+S+ +
Sbjct: 120 SKFAEGASYPDHTFLVEKMDDAVAPGQEYTYEWNISEDSGPTHNDPPCLTHIYYSYENLI 179
Query: 187 KDIASGLIGPLIICKKDSLDKEK-EKHIDREFVVMFSVVDENFSWYLEDNIKTYCSEPEK 245
+D SGLIGPL+ICKK +L ++ +K D+++V+MF+V DE+ SW
Sbjct: 180 QDFNSGLIGPLLICKKGTLTEDGIQKMFDKQYVLMFAVFDESKSWN-------------- 225
Query: 246 VDKDNEDFQESNRMYSVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFHGQALT 305
Q S+ MY+VNGY G++P +++CA D + W+L GM + ++ + F GQ L
Sbjct: 226 --------QSSSLMYTVNGYVNGTMPDITVCAYDHISWHLIGMSSGPELFSIHFSGQVLE 277
Query: 306 NKNYRIDTINLFPATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQVQECNKSSSKDN 365
++++ I L AT A M G+W +S H +AG+QA+ ++ C K + K
Sbjct: 278 QNHHKVSAITLVSATSTTANMTVSPEGKWPISSLIPKHFQAGMQAYIDIKNCAKKTRKPK 337
Query: 366 I----RGKHVRH--YYIAAEEIIWNYAPSGIDIFTKENLTAPGSDSAVFFEQGTTRIGGS 419
+ +H++ Y+IAAEE+IW+YAP K+ ++ + + +IG
Sbjct: 338 KLTRDQRRHIKRWEYFIAAEEVIWDYAPIIPANMDKKY-------RSLHLDNFSNQIGKH 390
Query: 420 YKKLVYREYTDASFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIG 479
YKK+VY++Y D SFT R E P + GILGPVI A+V DT+++ F N + SI P G
Sbjct: 391 YKKVVYKQYQDESFTKRLEN-PNNKEDGILGPVIRAQVRDTLKIVFKNMASRSYSIYPHG 449
Query: 480 VRFNKNNEGTYYSPNYNPQSRSVPPSASH-VAPTETFTYEWTVPKEVGPTNADPVCLAKM 538
V F+ Y + N S S + V P ET+TY+W + + PT D CL +
Sbjct: 450 VTFSP------YEDDVNSSSTSDNNTMIRAVQPGETYTYKWNILESDEPTENDAQCLTRP 503
Query: 539 YYSAVDPTKDIFTGLIGPMKICKKGSLHANGRQKDVDKEFYLFPTVFDENESLLLEDNIR 598
YYS VD T+DI +GLIG + ICK SL G Q+ D E VFDEN+S +EDNI
Sbjct: 504 YYSNVDITRDIASGLIGLLLICKSRSLDKRGIQRTADIEQKAVFAVFDENKSWYIEDNIY 563
Query: 599 MFTTAPDQVDKEDEDFQESNKMHSMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGI 658
F P++V ++D F ESN M ++NG++ + P L C D+V W+ S ++ I
Sbjct: 564 KFCENPEKVKRDDPKFYESNIMSTINGYVPESIPTLGFCFDDTVQWHFCSVRTHDNILTI 623
Query: 659 YFSGNTYLWRGERRDTANLFPQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTVNQC 718
+F+G+++++ DT LFP ++ + D GT+ + + ++ ++ K+ +C
Sbjct: 624 HFTGHSFIYGKRHEDTLTLFPMRGESVTVTMDNVGTWMLTTMNSNPRNKKLQLKFRDVKC 683
Query: 719 RRQSEDSTF 727
R ++ ++
Sbjct: 684 IRDDDEDSY 692
</PRE>
<PRE>
Score = 390 bits (1003), Expect = e-108
Identities = 243/693 (35%), Positives = 350/693 (50%), Gaps = 86/693 (12%)
Query: 371 VRHYYIAAEEIIWNYAPSGIDIFTKENLTAPGSDSAVFFEQGTTRIGGSYKKLVYREYTD 430
VR +Y+AA+ I WNY P T P S S+KK+VYREY +
Sbjct: 31 VRQFYVAAQSISWNYHPEP---------THPSSSP----------FATSFKKIVYREY-E 70
Query: 431 ASFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGVRFNKNNEGTY 490
A F K P G+LGP ++A+VGD ++V F NK PLSI P G++++K EG
Sbjct: 71 AYFQKEK---PPSRMSGLLGPTLYADVGDIMKVHFRNKADKPLSIHPQGIKYSKFAEGA- 126
Query: 491 YSPNYNPQSRSVPPSASHVAPTETFTYEWTVPKEVGPTNADPVCLAKMYYSAVDPTKDIF 550
+Y + V VAP + +TYEW + ++ GPT+ DP CL +YYS + +D
Sbjct: 127 ---SYPDHTFLVEKMDDAVAPGQEYTYEWNISEDSGPTHNDPPCLTHIYYSYENLIQDFN 183
Query: 551 TGLIGPMKICKKGSLHANGRQKDVDKEFYLFPTVFDENESLLLEDNIRMFTTAPDQVDKE 610
+GLIGP+ ICKKG+L +G QK DK++ L VFDE++S
Sbjct: 184 SGLIGPLLICKKGTLTEDGIQKMFDKQYVLMFAVFDESKSWN------------------ 225
Query: 611 DEDFQESNKMHSMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGIYFSGNTYLWRGE 670
Q S+ M+++NG++ G P +T+C D + W+L + ++ I+FSG
Sbjct: 226 ----QSSSLMYTVNGYVNGTMPDITVCAYDHISWHLIGMSSGPELFSIHFSGQVLEQNHH 281
Query: 671 RRDTANLFPQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTVNQCRRQSE------- 723
+ L TS T +M EG + + L H+ GM+ + C +++
Sbjct: 282 KVSAITLVSATSTTANMTVSPEGKWPISSLIPKHFQAGMQAYIDIKNCAKKTRKPKKLTR 341
Query: 724 DSTFYLGERTYYIAAVEVEWDYSP--QREWEKELHHLQEQNVSNAFLDKGEFYIGSKYKK 781
D ++ Y+IAA EV WDY+P +K+ L N SN IG YKK
Sbjct: 342 DQRRHIKRWEYFIAAEEVIWDYAPIIPANMDKKYRSLHLDNFSNQ--------IGKHYKK 393
Query: 782 VVYRQYTDSTFRVPVERKAEEEHLGILGPQLHADVGDKVKIIFKNMATRPYSIHAHGVQ- 840
VVY+QY D +F +E +E GILGP + A V D +KI+FKNMA+R YSI+ HGV
Sbjct: 394 VVYKQYQDESFTKRLENPNNKED-GILGPVIRAQVRDTLKIVFKNMASRSYSIYPHGVTF 452
Query: 841 -------TESST------VTPTLPGETLTYVWKIPERSGAGTEDSACIPWAYYSTVDQVK 887
SST + PGET TY W I E D+ C+ YYS VD +
Sbjct: 453 SPYEDDVNSSSTSDNNTMIRAVQPGETYTYKWNILESDEPTENDAQCLTRPYYSNVDITR 512
Query: 888 DLYSGLIGPLIVCRRPYLKVFNPRRK--LEFALLFLVFDENESWYLDDNIKTYSDHPEKV 945
D+ SGLIG L++C+ L +R +E +F VFDEN+SWY++DNI + ++PEKV
Sbjct: 513 DIASGLIGLLLICKSRSLDKRGIQRTADIEQKAVFAVFDENKSWYIEDNIYKFCENPEKV 572
Query: 946 NKDDEEFIESNKMHAINGRMFGNLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQY 1005
+DD +F ESN M ING + ++ L D V W+ + ++ T+HF GHSF Y
Sbjct: 573 KRDDPKFYESNIMSTINGYVPESIPTLGFCFDDTVQWHFCSVRTHDNILTIHFTGHSFIY 632
Query: 1006 KHRGVYSSDVFDIFPGTYQTLEMFPRTPGIWLL 1038
G D +FP +++ + G W+L
Sbjct: 633 ---GKRHEDTLTLFPMRGESVTVTMDNVGTWML 662
</PRE>
<PRE>
Score = 237 bits (605), Expect = 7e-62
Identities = 140/368 (38%), Positives = 194/368 (52%), Gaps = 45/368 (12%)
Query: 715 VNQCRRQSEDSTFYL-----GERTYYIAAVEVEWDYSPQREWEKELHHLQEQNVSNAFLD 769
+N R + +YL R YYIAA E+ WDYS + E ++ + E +
Sbjct: 1596 INSSRNPDNIAAWYLRSNNGNRRNYYIAAEELSWDYSKFTQRE-DIDDVPEHTI------ 1648
Query: 770 KGEFYIGSKYKKVVYRQYTDSTFRVPVERKAEEEHLGILGPQLHADVGDKVKIIFKNMAT 829
YKKVV+R+Y DSTF R EEHLGILGP + A+V D +++ FKN+A+
Sbjct: 1649 ---------YKKVVFRKYLDSTFTKLDPRGEYEEHLGILGPIIRAEVDDVIQVRFKNLAS 1699
Query: 830 RPYSIHAHGVQTESSTVTPTL---------------PGETLTYVWKIPERSGAGTEDSAC 874
RPYS+HAHG+ E S+ T P + TYVW ERSG + SAC
Sbjct: 1700 RPYSLHAHGLSYEKSSEGKTYEDDSPEWFKEDNAVQPNSSYTYVWHATERSGPESPGSAC 1759
Query: 875 IPWAYYSTVDQVKDLYSGLIGPLIVCRRPYLKVFN--PRRKLEFALLFLVFDENESWYLD 932
WAYYS V+ KD++SGLIGPL++CR+ L N P EF LLF+VFDE +SWY +
Sbjct: 1760 RAWAYYSAVNPEKDIHSGLIGPLLICRKGTLHKENNMPVDMREFVLLFMVFDEKKSWYYE 1819
Query: 933 DNIKTYSDHPEKVNKDDEEFIESNKMHAINGRMFGNLQGLTMHVGDEVNWYLMGMGNEID 992
E S+K HAING ++ NL GL M+ + V +L+ +G D
Sbjct: 1820 KKF------TRSWRLTSSEVKNSHKFHAINGMIY-NLPGLRMYEQEWVRLHLLNLGGSRD 1872
Query: 993 LHTVHFHGHSFQYKHRGVYSSDVFDIFPGTYQTLEMFPRTPGIWLLHCHVTDHIHAGMET 1052
+H VHFHG + + V+ + PG+++TLEM G WLL V ++ AGM+T
Sbjct: 1873 IHVVHFHGQTLLENGTQQHQLGVWPLLPGSFKTLEMKTSKAGWWLLDTEVGENQRAGMQT 1932
Query: 1053 TYTVLQNE 1060
+ ++ E
Sbjct: 1933 PFLIIDRE 1940
</PRE>
<PRE>
Score = 235 bits (600), Expect = 3e-61
Identities = 130/349 (37%), Positives = 190/349 (54%), Gaps = 8/349 (2%)
Query: 20 KEKHYYIGIIETTWDYASDHGEKKLISVDTEHSNIYLQNGPDRIGRLYKKALYLQYTDET 79
K Y+I E WDYA ++D ++ +++L N ++IG+ YKK +Y QY DE+
Sbjct: 348 KRWEYFIAAEEVIWDYAPIIPA----NMDKKYRSLHLDNFSNQIGKHYKKVVYKQYQDES 403
Query: 80 FRTTIEKP--VWLGFLGPIIKAETGDKVYVHLKNLASRPYTFHSHGITYYKEHEGAIYPD 137
F +E P G LGP+I+A+ D + + KN+ASR Y+ + HG+T + +E +
Sbjct: 404 FTKRLENPNNKEDGILGPVIRAQVRDTLKIVFKNMASRSYSIYPHGVT-FSPYEDDVNSS 462
Query: 138 NTTDFQRADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASGLIGPL 197
+T+D V PGE YTY E P E D C+TR Y+S++D +DIASGLIG L
Sbjct: 463 STSDNNTMIRAVQPGETYTYKWNILESDEPTENDAQCLTRPYYSNVDITRDIASGLIGLL 522
Query: 198 IICKKDSLDKEK-EKHIDREFVVMFSVVDENFSWYLEDNIKTYCSEPEKVDKDNEDFQES 256
+ICK SLDK ++ D E +F+V DEN SWY+EDNI +C PEKV +D+ F ES
Sbjct: 523 LICKSRSLDKRGIQRTADIEQKAVFAVFDENKSWYIEDNIYKFCENPEKVKRDDPKFYES 582
Query: 257 NRMYSVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFHGQALTNKNYRIDTINL 316
N M ++NGY S+P L C +D V+W+ + ++ F G + DT+ L
Sbjct: 583 NIMSTINGYVPESIPTLGFCFDDTVQWHFCSVRTHDNILTIHFTGHSFIYGKRHEDTLTL 642
Query: 317 FPATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQVQECNKSSSKDN 365
FP + N G WML+ N N LQ F+ +C + +D+
Sbjct: 643 FPMRGESVTVTMDNVGTWMLTTMNSNPRNKKLQLKFRDVKCIRDDDEDS 691
</PRE>
<PRE>
Score = 199 bits (507), Expect = 2e-50
Identities = 118/345 (34%), Positives = 181/345 (52%), Gaps = 30/345 (8%)
Query: 22 KHYYIGIIETTWDYASDHGEKKLISVDTEHSNIYLQNGPDRIGRLYKKALYLQYTDETFR 81
++YYI E +WDY S +++ I EH+ +YKK ++ +Y D TF
Sbjct: 1618 RNYYIAAEELSWDY-SKFTQREDIDDVPEHT-------------IYKKVVFRKYLDSTFT 1663
Query: 82 TTIEKPVW---LGFLGPIIKAETGDKVYVHLKNLASRPYTFHSHGITYYKEHEGAIYPDN 138
+ + LG LGPII+AE D + V KNLASRPY+ H+HG++Y K EG Y D+
Sbjct: 1664 KLDPRGEYEEHLGILGPIIRAEVDDVIQVRFKNLASRPYSLHAHGLSYEKSSEGKTYEDD 1723
Query: 139 TTDFQRADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASGLIGPLI 198
+ ++ + D+ V P YTY+ ATE P C Y+S ++ KDI SGLIGPL+
Sbjct: 1724 SPEWFKEDNAVQPNSSYTYVWHATERSGPESPGSACRAWAYYSAVNPEKDIHSGLIGPLL 1783
Query: 199 ICKKDSLDKEKEKHID-REFVVMFSVVDENFSWYLEDNIKTYCSEPEKVDKDNEDFQESN 257
IC+K +L KE +D REFV++F V DE SWY E + + + S+
Sbjct: 1784 ICRKGTLHKENNMPVDMREFVLLFMVFDEKKSWYYEKKF------TRSWRLTSSEVKNSH 1837
Query: 258 RMYSVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFHGQALT---NKNYRIDTI 314
+ +++NG + +LPGL M ++ V+ +L +G D+H FHGQ L + +++
Sbjct: 1838 KFHAINGMIY-NLPGLRMYEQEWVRLHLLNLGGSRDIHVVHFHGQTLLENGTQQHQLGVW 1896
Query: 315 NLFPATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQV--QEC 357
L P + M G W+L + + +AG+Q F + +EC
Sbjct: 1897 PLLPGSFKTLEMKTSKAGWWLLDTEVGENQRAGMQTPFLIIDREC 1941
</PRE>
<PRE>
Score = 193 bits (491), Expect = 1e-48
Identities = 138/428 (32%), Positives = 211/428 (49%), Gaps = 54/428 (12%)
Query: 356 ECNKSSSKDNIRGKHVR-------HYYIAAEEIIWNYAPSGIDIFTKENLTAPGSDSAVF 408
+ N S + DNI ++R +YYIAAEE+ W+Y+ FT+ + +
Sbjct: 1595 DINSSRNPDNIAAWYLRSNNGNRRNYYIAAEELSWDYSK-----FTQREDIDDVPEHTI- 1648
Query: 409 FEQGTTRIGGSYKKLVYREYTDASFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNK 468
YKK+V+R+Y D++FT RG EEHLGILGP+I AEV D I+V F N
Sbjct: 1649 -----------YKKVVFRKYLDSTFTKLDPRGEYEEHLGILGPIIRAEVDDVIQVRFKNL 1697
Query: 469 GAYPLSIEPIGVRFNKNNEGTYY---SPNYNPQSRSVPPSASHVAPTETFTYEWTVPKEV 525
+ P S+ G+ + K++EG Y SP + + +V P++S +TY W +
Sbjct: 1698 ASRPYSLHAHGLSYEKSSEGKTYEDDSPEWFKEDNAVQPNSS-------YTYVWHATERS 1750
Query: 526 GPTNADPVCLAKMYYSAVDPTKDIFTGLIGPMKICKKGSLHANGRQKDVDKEFYLFPTVF 585
GP + C A YYSAV+P KDI +GLIGP+ IC+KG+LH +EF L VF
Sbjct: 1751 GPESPGSACRAWAYYSAVNPEKDIHSGLIGPLLICRKGTLHKENNMPVDMREFVLLFMVF 1810
Query: 586 DENESLLLEDNIRMFTTAPDQVDKEDEDFQESNKMHSMNGFMYGNQPGLTMCKGDSVVWY 645
DE +S E + FT + E + S+K H++NG +Y N PGL M + + V +
Sbjct: 1811 DEKKSWYYE---KKFTRSWRLTSSE---VKNSHKFHAINGMIY-NLPGLRMYEQEWVRLH 1863
Query: 646 LFSAGNEADVHGIYFSGNTYLWRGERRDTAN---LFPQTSLTLHMWPDTEGTFNVECLTT 702
L + G D+H ++F G T L G ++ L P + TL M G + ++
Sbjct: 1864 LLNLGGSRDIHVVHFHGQTLLENGTQQHQLGVWPLLPGSFKTLEMKTSKAGWWLLDTEVG 1923
Query: 703 DHYTGGMKQKYTV--NQCRRQSEDSTFYLGERTYYIAAVEVEWDYSPQREWEKELHHLQE 760
++ GM+ + + +C+ ST + + I A E W + W+ +L L
Sbjct: 1924 ENQRAGMQTPFLIIDRECKMPMGLSTGLIADS--QIKASEF-WGH-----WQPKLARLNN 1975
Query: 761 QNVSNAFL 768
NA++
Sbjct: 1976 GGSYNAWI 1983
</PRE>
<PRE>
><a name = 462045></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=00462045&dopt=GenPept" >sp|P12259|FA5_HUMAN</a> Coagulation factor V precursor (Activated protein C cofactor)
Length = 2224
Score = 399 bits (1026), Expect = e-110
Identities = 232/675 (34%), Positives = 361/675 (53%), Gaps = 48/675 (7%)
Query: 67 YKKALYLQYTDETFRTTIEKPVWLGFLGPIIKAETGDKVYVHLKNLASRPYTFHSHGITY 126
+KK +Y +Y + F+ + G LGP + AE GD + VH KN A +P + H GI Y
Sbjct: 61 FKKIVYREY-EPYFKKEKPQSTISGLLGPTLYAEVGDIIKVHFKNKADKPLSIHPQGIRY 119
Query: 127 YKEHEGAIYPDNTTDFQRADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAP 186
K EGA Y D+T ++ DD V PG +YTY +E+ P D C+T IY+SH +
Sbjct: 120 SKLSEGASYLDHTFPAEKMDDAVAPGREYTYEWSISEDSGPTHDDPPCLTHIYYSHENLI 179
Query: 187 KDIASGLIGPLIICKKDSLDKE-KEKHIDREFVVMFSVVDENFSWYLEDNIKTYCSEPEK 245
+D SGLIGPL+ICKK +L + +K D++ V++F+V DE+ SW
Sbjct: 180 EDFNSGLIGPLLICKKGTLTEGGTQKTFDKQIVLLFAVFDESKSWS-------------- 225
Query: 246 VDKDNEDFQESNRMYSVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFHGQALT 305
Q S+ MY+VNGY G++P +++CA D + W+L GM + ++ + F+GQ L
Sbjct: 226 --------QSSSLMYTVNGYVNGTMPDITVCAHDHISWHLLGMSSGPELFSIHFNGQVLE 277
Query: 306 NKNYRIDTINLFPATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQVQEC-NKSSSKD 364
++++ I L AT A M G+W++S HL+AG+QA+ ++ C K+ +
Sbjct: 278 QNHHKVSAITLVSATSTTANMTVGPEGKWIISSLTPKHLQAGMQAYIDIKNCPKKTRNLK 337
Query: 365 NIRGKHVRH-----YYIAAEEIIWNYAPSGIDIFTKENLTAPGSDSAVFFEQGTTRIGGS 419
I + RH Y+IAAEE+IW+YAP K+ + + + +IG
Sbjct: 338 KITREQRRHMKRWEYFIAAEEVIWDYAPVIPANMDKKYRSQ-------HLDNFSNQIGKH 390
Query: 420 YKKLVYREYTDASFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIG 479
YKK++Y +Y D SFT P + GILGP+I A+V DT+++ F N + P SI P G
Sbjct: 391 YKKVMYTQYEDESFTKHTVN-PNMKEDGILGPIIRAQVRDTLKIVFKNMASRPYSIYPHG 449
Query: 480 VRFNKNNE---GTYYSPNYNPQSRSVPPSASHVAPTETFTYEWTVPKEVGPTNADPVCLA 536
V F+ + ++ S N R+V P ET+TY+W + + PT D CL
Sbjct: 450 VTFSPYEDEVNSSFTSGRNNTMIRAVQPG-------ETYTYKWNILEFDEPTENDAQCLT 502
Query: 537 KMYYSAVDPTKDIFTGLIGPMKICKKGSLHANGRQKDVDKEFYLFPTVFDENESLLLEDN 596
+ YYS VD +DI +GLIG + ICK SL G Q+ D E VFDEN+S LEDN
Sbjct: 503 RPYYSDVDIMRDIASGLIGLLLICKSRSLDRRGIQRAADIEQQAVFAVFDENKSWYLEDN 562
Query: 597 IRMFTTAPDQVDKEDEDFQESNKMHSMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVH 656
I F PD+V ++D F ESN M ++NG++ + L C D+V W+ S G + ++
Sbjct: 563 INKFCENPDEVKRDDPKFYESNIMSTINGYVPESITTLGFCFDDTVQWHFCSVGTQNEIL 622
Query: 657 GIYFSGNTYLWRGERRDTANLFPQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTVN 716
I+F+G+++++ DT LFP ++ + D GT+ + + + + ++ K+
Sbjct: 623 TIHFTGHSFIYGKRHEDTLTLFPMRGESVTVTMDNVGTWMLTSMNSSPRSKKLRLKFRDV 682
Query: 717 QCRRQSEDSTFYLGE 731
+C ++ ++ + E
Sbjct: 683 KCIPDDDEDSYEIFE 697
</PRE>
<PRE>
Score = 383 bits (984), Expect = e-106
Identities = 236/695 (33%), Positives = 351/695 (49%), Gaps = 89/695 (12%)
Query: 371 VRHYYIAAEEIIWNYAPSGIDIFTKENLTAPGSDSAVFFEQGTTRIGGSYKKLVYREYTD 430
+R +Y+AA+ I W+Y P + ++T S+KK+VYREY
Sbjct: 31 LRQFYVAAQGISWSYRPEPTNSSLNLSVT-------------------SFKKIVYREYEP 71
Query: 431 ASFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGAYPLSIEPIGVRFNKNNEGTY 490
K+ P+ G+LGP ++AEVGD I+V F NK PLSI P G+R++K +EG
Sbjct: 72 YF----KKEKPQSTISGLLGPTLYAEVGDIIKVHFKNKADKPLSIHPQGIRYSKLSEGAS 127
Query: 491 YSPNYNPQSRSVPPSASHVAPTETFTYEWTVPKEVGPTNADPVCLAKMYYSAVDPTKDIF 550
Y + P + VAP +TYEW++ ++ GPT+ DP CL +YYS + +D
Sbjct: 128 YLDHTFPAEKM----DDAVAPGREYTYEWSISEDSGPTHDDPPCLTHIYYSHENLIEDFN 183
Query: 551 TGLIGPMKICKKGSLHANGRQKDVDKEFYLFPTVFDENESLLLEDNIRMFTTAPDQVDKE 610
+GLIGP+ ICKKG+L G QK DK+ L VFDE++S
Sbjct: 184 SGLIGPLLICKKGTLTEGGTQKTFDKQIVLLFAVFDESKSWS------------------ 225
Query: 611 DEDFQESNKMHSMNGFMYGNQPGLTMCKGDSVVWYLFSAGNEADVHGIYFSGNTYLWRGE 670
Q S+ M+++NG++ G P +T+C D + W+L + ++ I+F+G
Sbjct: 226 ----QSSSLMYTVNGYVNGTMPDITVCAHDHISWHLLGMSSGPELFSIHFNGQVLEQNHH 281
Query: 671 RRDTANLFPQTSLTLHMWPDTEGTFNVECLTTDHYTGGMKQKYTVNQCRRQSEDSTFYLG 730
+ L TS T +M EG + + LT H GM+ + C +++ +
Sbjct: 282 KVSAITLVSATSTTANMTVGPEGKWIISSLTPKHLQAGMQAYIDIKNCPKKTRNLKKITR 341
Query: 731 ERT-------YYIAAVEVEWDYSP--QREWEKELHHLQEQNVSNAFLDKGEFYIGSKYKK 781
E+ Y+IAA EV WDY+P +K+ N SN IG YKK
Sbjct: 342 EQRRHMKRWEYFIAAEEVIWDYAPVIPANMDKKYRSQHLDNFSNQ--------IGKHYKK 393
Query: 782 VVYRQYTDSTF-RVPVERKAEEEHLGILGPQLHADVGDKVKIIFKNMATRPYSIHAHGVQ 840
V+Y QY D +F + V +E+ GILGP + A V D +KI+FKNMA+RPYSI+ HGV
Sbjct: 394 VMYTQYEDESFTKHTVNPNMKED--GILGPIIRAQVRDTLKIVFKNMASRPYSIYPHGVT 451
Query: 841 ---------------TESSTVTPTLPGETLTYVWKIPERSGAGTEDSACIPWAYYSTVDQ 885
++ + PGET TY W I E D+ C+ YYS VD
Sbjct: 452 FSPYEDEVNSSFTSGRNNTMIRAVQPGETYTYKWNILEFDEPTENDAQCLTRPYYSDVDI 511
Query: 886 VKDLYSGLIGPLIVCRRPYLKVFNPRRK--LEFALLFLVFDENESWYLDDNIKTYSDHPE 943
++D+ SGLIG L++C+ L +R +E +F VFDEN+SWYL+DNI + ++P+
Sbjct: 512 MRDIASGLIGLLLICKSRSLDRRGIQRAADIEQQAVFAVFDENKSWYLEDNINKFCENPD 571
Query: 944 KVNKDDEEFIESNKMHAINGRMFGNLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSF 1003
+V +DD +F ESN M ING + ++ L D V W+ +G + ++ T+HF GHSF
Sbjct: 572 EVKRDDPKFYESNIMSTINGYVPESITTLGFCFDDTVQWHFCSVGTQNEILTIHFTGHSF 631
Query: 1004 QYKHRGVYSSDVFDIFPGTYQTLEMFPRTPGIWLL 1038
Y G D +FP +++ + G W+L
Sbjct: 632 IY---GKRHEDTLTLFPMRGESVTVTMDNVGTWML 663
</PRE>
<PRE>
Score = 236 bits (603), Expect = 1e-61
Identities = 138/370 (37%), Positives = 199/370 (53%), Gaps = 45/370 (12%)
Query: 715 VNQCRRQSEDSTFYL-----GERTYYIAAVEVEWDYSP--QREWEKELHHLQEQNVSNAF 767
+N R + +YL R YYIAA E+ WDYS QRE + E
Sbjct: 1558 INSSRDPDNIAAWYLRSNNGNRRNYYIAAEEISWDYSEFVQRETDIE------------- 1604
Query: 768 LDKGEFYIGSKYKKVVYRQYTDSTFRVPVERKAEEEHLGILGPQLHADVGDKVKIIFKNM 827
D + + YKKVV+R+Y DSTF R EEHLGILGP + A+V D +++ FKN+
Sbjct: 1605 -DSDDIPEDTTYKKVVFRKYLDSTFTKRDPRGEYEEHLGILGPIIRAEVDDVIQVRFKNL 1663
Query: 828 ATRPYSIHAHGVQTESSTVTPTL---------------PGETLTYVWKIPERSGAGTEDS 872
A+RPYS+HAHG+ E S+ T P + TYVW ERSG + S
Sbjct: 1664 ASRPYSLHAHGLSYEKSSEGKTYEDDSPEWFKEDNAVQPNSSYTYVWHATERSGPESPGS 1723
Query: 873 ACIPWAYYSTVDQVKDLYSGLIGPLIVCRRPYLKVFN--PRRKLEFALLFLVFDENESWY 930
AC WAYYS V+ KD++SGLIGPL++C++ L + P EF LLF+ FDE +SWY
Sbjct: 1724 ACRAWAYYSAVNPEKDIHSGLIGPLLICQKGILHKDSNMPVDMREFVLLFMTFDEKKSWY 1783
Query: 931 LDDNIKTYSDHPEKVNKDDEEFIESNKMHAINGRMFGNLQGLTMHVGDEVNWYLMGMGNE 990
+ ++ E +S++ HAING ++ +L GL M+ + V +L+ +G
Sbjct: 1784 YEKKSRS------SWRLTSSEMKKSHEFHAINGMIY-SLPGLKMYEQEWVRLHLLNIGGS 1836
Query: 991 IDLHTVHFHGHSFQYKHRGVYSSDVFDIFPGTYQTLEMFPRTPGIWLLHCHVTDHIHAGM 1050
D+H VHFHG + + V+ + PG+++TLEM PG WLL+ V ++ AGM
Sbjct: 1837 QDIHVVHFHGQTLLENGNKQHQLGVWPLLPGSFKTLEMKASKPGWWLLNTEVGENQRAGM 1896
Query: 1051 ETTYTVLQNE 1060
+T + ++ +
Sbjct: 1897 QTPFLIMDRD 1906
</PRE>
<PRE>
Score = 220 bits (561), Expect = 9e-57
Identities = 128/352 (36%), Positives = 184/352 (51%), Gaps = 13/352 (3%)
Query: 20 KEKHYYIGIIETTWDYASDHGEKKLISVDTEHSNIYLQNGPDRIGRLYKKALYLQYTDET 79
K Y+I E WDYA ++D ++ + +L N ++IG+ YKK +Y QY DE+
Sbjct: 348 KRWEYFIAAEEVIWDYAPVIPA----NMDKKYRSQHLDNFSNQIGKHYKKVMYTQYEDES 403
Query: 80 FRTTIEKPVWL--GFLGPIIKAETGDKVYVHLKNLASRPYTFHSHGIT---YYKEHEGAI 134
F P G LGPII+A+ D + + KN+ASRPY+ + HG+T Y E +
Sbjct: 404 FTKHTVNPNMKEDGILGPIIRAQVRDTLKIVFKNMASRPYSIYPHGVTFSPYEDEVNSSF 463
Query: 135 YPDNTTDFQRADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASGLI 194
RA V PGE YTY E P E D C+TR Y+S +D +DIASGLI
Sbjct: 464 TSGRNNTMIRA---VQPGETYTYKWNILEFDEPTENDAQCLTRPYYSDVDIMRDIASGLI 520
Query: 195 GPLIICKKDSLDKEK-EKHIDREFVVMFSVVDENFSWYLEDNIKTYCSEPEKVDKDNEDF 253
G L+ICK SLD+ ++ D E +F+V DEN SWYLEDNI +C P++V +D+ F
Sbjct: 521 GLLLICKSRSLDRRGIQRAADIEQQAVFAVFDENKSWYLEDNINKFCENPDEVKRDDPKF 580
Query: 254 QESNRMYSVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFHGQALTNKNYRIDT 313
ESN M ++NGY S+ L C +D V+W+ +G + ++ F G + DT
Sbjct: 581 YESNIMSTINGYVPESITTLGFCFDDTVQWHFCSVGTQNEILTIHFTGHSFIYGKRHEDT 640
Query: 314 INLFPATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQVQECNKSSSKDN 365
+ LFP + N G WML+ N + L+ F+ +C +D+
Sbjct: 641 LTLFPMRGESVTVTMDNVGTWMLTSMNSSPRSKKLRLKFRDVKCIPDDDEDS 692
</PRE>
<PRE>
Score = 204 bits (519), Expect = 7e-52
Identities = 119/342 (34%), Positives = 182/342 (52%), Gaps = 24/342 (7%)
Query: 22 KHYYIGIIETTWDYASDHGEKKLISVDTEHSNIYLQNGPDRIGRLYKKALYLQYTDETFR 81
++YYI E +WDY+ E D E S+ ++ YKK ++ +Y D TF
Sbjct: 1580 RNYYIAAEEISWDYS----EFVQRETDIEDSDDIPED------TTYKKVVFRKYLDSTFT 1629
Query: 82 TTIEKPVW---LGFLGPIIKAETGDKVYVHLKNLASRPYTFHSHGITYYKEHEGAIYPDN 138
+ + LG LGPII+AE D + V KNLASRPY+ H+HG++Y K EG Y D+
Sbjct: 1630 KRDPRGEYEEHLGILGPIIRAEVDDVIQVRFKNLASRPYSLHAHGLSYEKSSEGKTYEDD 1689
Query: 139 TTDFQRADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASGLIGPLI 198
+ ++ + D+ V P YTY+ ATE P C Y+S ++ KDI SGLIGPL+
Sbjct: 1690 SPEWFKEDNAVQPNSSYTYVWHATERSGPESPGSACRAWAYYSAVNPEKDIHSGLIGPLL 1749
Query: 199 ICKKDSLDKEKEKHID-REFVVMFSVVDENFSWYLEDNIKTYCSEPEKVDKDNEDFQESN 257
IC+K L K+ +D REFV++F DE SWY E ++ + + ++S+
Sbjct: 1750 ICQKGILHKDSNMPVDMREFVLLFMTFDEKKSWYYEKKSRS------SWRLTSSEMKKSH 1803
Query: 258 RMYSVNGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFHGQALT---NKNYRIDTI 314
+++NG + SLPGL M ++ V+ +L +G D+H FHGQ L NK +++
Sbjct: 1804 EFHAINGMIY-SLPGLKMYEQEWVRLHLLNIGGSQDIHVVHFHGQTLLENGNKQHQLGVW 1862
Query: 315 NLFPATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFFQVQE 356
L P + M A PG W+L+ + + +AG+Q F + +
Sbjct: 1863 PLLPGSFKTLEMKASKPGWWLLNTEVGENQRAGMQTPFLIMD 1904
</PRE>
<PRE>
Score = 193 bits (490), Expect = 2e-48
Identities = 128/377 (33%), Positives = 189/377 (49%), Gaps = 42/377 (11%)
Query: 358 NKSSSKDNIRGKHVR-------HYYIAAEEIIWNYAPSGIDIFTKENLTAPGSDSAVFFE 410
N S DNI ++R +YYIAAEEI W+Y+ F + SD
Sbjct: 1559 NSSRDPDNIAAWYLRSNNGNRRNYYIAAEEISWDYSE-----FVQRETDIEDSDD---IP 1610
Query: 411 QGTTRIGGSYKKLVYREYTDASFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGA 470
+ TT YKK+V+R+Y D++FT R RG EEHLGILGP+I AEV D I+V F N +
Sbjct: 1611 EDTT-----YKKVVFRKYLDSTFTKRDPRGEYEEHLGILGPIIRAEVDDVIQVRFKNLAS 1665
Query: 471 YPLSIEPIGVRFNKNNEGTYY---SPNYNPQSRSVPPSASHVAPTETFTYEWTVPKEVGP 527
P S+ G+ + K++EG Y SP + + +V P++S +TY W + GP
Sbjct: 1666 RPYSLHAHGLSYEKSSEGKTYEDDSPEWFKEDNAVQPNSS-------YTYVWHATERSGP 1718
Query: 528 TNADPVCLAKMYYSAVDPTKDIFTGLIGPMKICKKGSLHANGRQKDVDKEFYLFPTVFDE 587
+ C A YYSAV+P KDI +GLIGP+ IC+KG LH + +EF L FDE
Sbjct: 1719 ESPGSACRAWAYYSAVNPEKDIHSGLIGPLLICQKGILHKDSNMPVDMREFVLLFMTFDE 1778
Query: 588 NESLLLEDNIRMFTTAPDQVDKEDEDFQESNKMHSMNGFMYGNQPGLTMCKGDSVVWYLF 647
+S E R + ++S++ H++NG +Y + PGL M + + V +L
Sbjct: 1779 KKSWYYEKKSR------SSWRLTSSEMKKSHEFHAINGMIY-SLPGLKMYEQEWVRLHLL 1831
Query: 648 SAGNEADVHGIYFSGNTYLWRGERRDTAN---LFPQTSLTLHMWPDTEGTFNVECLTTDH 704
+ G D+H ++F G T L G ++ L P + TL M G + + ++
Sbjct: 1832 NIGGSQDIHVVHFHGQTLLENGNKQHQLGVWPLLPGSFKTLEMKASKPGWWLLNTEVGEN 1891
Query: 705 YTGGMKQKYTV--NQCR 719
GM+ + + CR
Sbjct: 1892 QRAGMQTPFLIMDRDCR 1908
</PRE>
<PRE>
Score = 149 bits (376), Expect = 3e-35
Identities = 96/337 (28%), Positives = 159/337 (46%), Gaps = 64/337 (18%)
Query: 732 RTYYIAAVEVEWDYSPQREWEKELHHLQEQNVSNAFLDKGEFYIGSKYKKVVYRQYTDST 791
R +Y+AA + W Y P+ +N+ L+ + +KK+VYR+Y +
Sbjct: 32 RQFYVAAQGISWSYRPEP--------------TNSSLNLSV----TSFKKIVYREY-EPY 72
Query: 792 FRVPVERKAEEEHLGILGPQLHADVGDKVKIIFKNMATRPYSIHAHGVQTE-----SSTV 846
F+ + K + G+LGP L+A+VGD +K+ FKN A +P SIH G++ +S +
Sbjct: 73 FK---KEKPQSTISGLLGPTLYAEVGDIIKVHFKNKADKPLSIHPQGIRYSKLSEGASYL 129
Query: 847 TPTLPGETL----------TYVWKIPERSGAGTEDSACIPWAYYSTVDQVKDLYSGLIGP 896
T P E + TY W I E SG +D C+ YYS + ++D SGLIGP
Sbjct: 130 DHTFPAEKMDDAVAPGREYTYEWSISEDSGPTHDDPPCLTHIYYSHENLIEDFNSGLIGP 189
Query: 897 LIVCRRPYLKVFNPRRKLE--FALLFLVFDENESWYLDDNIKTYSDHPEKVNKDDEEFIE 954
L++C++ L ++ + LLF VFDE++SW ++
Sbjct: 190 LLICKKGTLTEGGTQKTFDKQIVLLFAVFDESKSWSQSSSL------------------- 230
Query: 955 SNKMHAINGRMFGNLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRGVYSSD 1014
M+ +NG + G + +T+ D ++W+L+GM + +L ++HF+G + H V
Sbjct: 231 ---MYTVNGYVNGTMPDITVCAHDHISWHLLGMSSGPELFSIHFNGQVLEQNHHKV---S 284
Query: 1015 VFDIFPGTYQTLEMFPRTPGIWLLHCHVTDHIHAGME 1051
+ T T M G W++ H+ AGM+
Sbjct: 285 AITLVSATSTTANMTVGPEGKWIISSLTPKHLQAGMQ 321
</PRE>
<PRE>
><a name = 1351670></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=01351670&dopt=GenPept" >sp|Q09920|YAK8_SCHPO</a> Putative multicopper oxidase C1F7.08 precursor
Length = 622
Score = 54.7 bits (130), Expect = 9e-07
Identities = 32/114 (28%), Positives = 51/114 (44%), Gaps = 29/114 (25%)
Query: 968 NLQGLTMHVGDEVNWYLMGMGNEIDL---------HTVHFHGHSFQYKHRG-----VYSS 1013
NL+ +T G N Y+ G+ +D+ H H HGH+FQ RG +YS
Sbjct: 384 NLEPVTY--GPYTNAYIFEYGDVVDVIIDNHDTGKHPFHLHGHTFQVLERGEENAGLYSD 441
Query: 1014 -------------DVFDIFPGTYQTLEMFPRTPGIWLLHCHVTDHIHAGMETTY 1054
D +I PG++ + PG W++HCH+ H+ +G+ T+
Sbjct: 442 QESHTYYDNPMRRDTVEIEPGSFIVIRFIADNPGAWVIHCHIEWHMESGLLATF 495
</PRE>
<PRE>
Score = 36.2 bits (82), Expect = 0.33
Identities = 15/43 (34%), Positives = 24/43 (54%)
Query: 310 RIDTINLFPATLFDAYMVAQNPGEWMLSCQNLNHLKAGLQAFF 352
R DT+ + P + +A NPG W++ C H+++GL A F
Sbjct: 453 RRDTVEIEPGSFIVIRFIADNPGAWVIHCHIEWHMESGLLATF 495
</PRE>
<PRE>
><a name = 2833227></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02833227&dopt=GenPept" >sp|Q12541|LAC1_AGABI</a> LACCASE I PRECURSOR (BENZENEDIOL:OXYGEN OXIDOREDUCTASE) (URISHIOL
OXIDASE) (DIPHENOL OXIDASE)
Length = 520
Score = 46.2 bits (108), Expect = 3e-04
Identities = 27/82 (32%), Positives = 35/82 (41%), Gaps = 13/82 (15%)
Query: 994 HTVHFHGHSFQYKHRGVYSSDVF--------DIFP--GTYQTLEMFPRTPGIWLLHCHVT 1043
H H HGH+F + D F D++P G T F PG W LHCH+
Sbjct: 417 HPFHLHGHNFDVVLAS--NDDTFNFKNPPRRDVYPINGGNTTFRFFTDNPGAWFLHCHID 474
Query: 1044 DHIHAGMETTYTVLQNEDTKSG 1065
H+ AG+ + ED SG
Sbjct: 475 WHLEAGLAIVFAEAP-EDNVSG 495
</PRE>
<PRE>
><a name = 2833228></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02833228&dopt=GenPept" >sp|Q12542|LAC2_AGABI</a> LACCASE II PRECURSOR (BENZENEDIOL:OXYGEN OXIDOREDUCTASE) (URISHIOL
OXIDASE) (DIPHENOL OXIDASE)
Length = 520
Score = 46.2 bits (108), Expect = 3e-04
Identities = 27/82 (32%), Positives = 35/82 (41%), Gaps = 13/82 (15%)
Query: 994 HTVHFHGHSFQYKHRGVYSSDVF--------DIFP--GTYQTLEMFPRTPGIWLLHCHVT 1043
H H HGH+F + D F D++P G T F PG W LHCH+
Sbjct: 417 HPFHLHGHNFDVVLAS--NDDTFNFVNPPRRDVYPINGGNTTFRFFTDNPGAWFLHCHID 474
Query: 1044 DHIHAGMETTYTVLQNEDTKSG 1065
H+ AG+ + ED SG
Sbjct: 475 WHLEAGLAIVFAEAP-EDNVSG 495
</PRE>
<PRE>
><a name = 2493321></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02493321&dopt=GenPept" >sp|Q40588|ASO_TOBAC</a> L-ASCORBATE OXIDASE PRECURSOR (ASCORBASE) (ASO)
Length = 578
Score = 44.7 bits (104), Expect = 0.001
Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 16/75 (21%)
Query: 992 DLHTVHFHGHSF--------QYKHRGVYSSDVFD--------IFPGTYQTLEMFPRTPGI 1035
++H H HGH F ++ + V ++ + IFP + L PG+
Sbjct: 470 EIHPWHLHGHDFWVLGYGEGKFSEKDVKKFNLKNPPLRNTAVIFPFGWTALRFVTDNPGV 529
Query: 1036 WLLHCHVTDHIHAGM 1050
W HCH+ H+H GM
Sbjct: 530 WAFHCHIEPHLHMGM 544
</PRE>
<PRE>
Score = 43.5 bits (101), Expect = 0.002
Identities = 41/133 (30%), Positives = 57/133 (42%), Gaps = 23/133 (17%)
Query: 92 FLGPIIKAETGDKVYVHLKN-LASRPYTFHSHGITYYKEHEGAIYPDNTTDFQRADDKVY 150
F GP I+A+ GD V VHL N L + H HGI G + D T + +
Sbjct: 58 FPGPTIRAKAGDTVAVHLTNKLHTEGVVIHWHGI----RQIGTPWADGTAAISQC--AIN 111
Query: 151 PGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASGLIGPLIICKKDSLDKEKE 210
PGE + Y + T YH H + ++GL G LI+ + + EKE
Sbjct: 112 PGETFLYRFKVDK----------AGTYFYHGHYGMQR--SAGLYGSLIV---EVGEGEKE 156
Query: 211 K-HIDREFVVMFS 222
H D EF ++ S
Sbjct: 157 PFHYDGEFNLLLS 169
</PRE>
<PRE>
><a name = 114270></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=00114270&dopt=GenPept" >sp|P14133|ASO_CUCSA</a> L-ASCORBATE OXIDASE PRECURSOR (ASCORBASE) (ASO)
Length = 587
Score = 43.9 bits (102), Expect = 0.002
Identities = 37/132 (28%), Positives = 55/132 (41%), Gaps = 21/132 (15%)
Query: 92 FLGPIIKAETGDKVYVHLKN-LASRPYTFHSHGITYYKEHEGAIYPDNTTDFQRADDKVY 150
F GP I+A GD V V L N L + H HGI G + D T + +
Sbjct: 66 FPGPTIRANAGDIVVVELTNKLHTEGVVIHWHGIL----QRGTPWADGTASISQC--AIN 119
Query: 151 PGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASGLIGPLIICKKDSLDKEKE 210
PGE +TY + + T YH H+ + ++GL G LI+ + + +
Sbjct: 120 PGETFTYRFVVDK----------AGTYFYHGHLGMQR--SAGLYGSLIVDPPEG--RSEP 165
Query: 211 KHIDREFVVMFS 222
H D E ++ S
Sbjct: 166 FHYDEEINLLLS 177
</PRE>
<PRE>
Score = 43.9 bits (102), Expect = 0.002
Identities = 22/83 (26%), Positives = 32/83 (38%), Gaps = 17/83 (20%)
Query: 989 NEIDLHTVHFHGHSFQ---YKHRGVYSSD--------------VFDIFPGTYQTLEMFPR 1031
N ++H H HGH F Y Y+ + IFP + +
Sbjct: 475 NMSEIHPWHLHGHDFWVLGYGEGKFYAPEDEKKLNLKNPPLRNTVVIFPYGWTAIRFVAD 534
Query: 1032 TPGIWLLHCHVTDHIHAGMETTY 1054
PG+W HCH+ H+H GM +
Sbjct: 535 NPGVWAFHCHIEPHLHMGMGVVF 557
</PRE>
<PRE>
><a name = 543859></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=00543859&dopt=GenPept" >sp|P37064|ASO_CUCPM</a> L-ASCORBATE OXIDASE (ASCORBASE) (ASO)
Length = 552
Score = 43.1 bits (100), Expect = 0.003
Identities = 39/132 (29%), Positives = 55/132 (41%), Gaps = 21/132 (15%)
Query: 92 FLGPIIKAETGDKVYVHLKN-LASRPYTFHSHGITYYKEHEGAIYPDNTTDFQRADDKVY 150
F GP I+A GD V V L N L + H HGI G + D T + +
Sbjct: 31 FPGPTIRANAGDSVVVELTNKLHTEGVVIHWHGIL----QRGTPWADGTASISQC--AIN 84
Query: 151 PGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASGLIGPLIICKKDSLDKEKE 210
PGE + Y +PG T YH H+ + ++GL G LI+ K++
Sbjct: 85 PGETFFYNFTV---DNPG-------TFFYHGHLGMQR--SAGLYGSLIVDPPQG--KKEP 130
Query: 211 KHIDREFVVMFS 222
H D E ++ S
Sbjct: 131 FHYDGEINLLLS 142
</PRE>
<PRE>
Score = 42.0 bits (97), Expect = 0.006
Identities = 22/82 (26%), Positives = 32/82 (38%), Gaps = 16/82 (19%)
Query: 989 NEIDLHTVHFHGHSFQYKHRG--VYSSD--------------VFDIFPGTYQTLEMFPRT 1032
N + H H HGH F G +S++ IFP + +
Sbjct: 440 NLSETHPWHLHGHDFWVLGYGDGKFSAEEESSLNLKNPPLRNTVVIFPYGWTAIRFVADN 499
Query: 1033 PGIWLLHCHVTDHIHAGMETTY 1054
PG+W HCH+ H+H GM +
Sbjct: 500 PGVWAFHCHIEPHLHMGMGVVF 521
</PRE>
<PRE>
><a name = 2827764></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02827764&dopt=GenPept" >sp|P24792|ASO_CUCMA</a> L-ASCORBATE OXIDASE PRECURSOR (ASCORBASE)
Length = 579
Score = 42.4 bits (98), Expect = 0.005
Identities = 22/84 (26%), Positives = 34/84 (40%), Gaps = 20/84 (23%)
Query: 989 NEIDLHTVHFHGHSF------------------QYKHRGVYSSDVFDIFPGTYQTLEMFP 1030
N ++H H HGH F K+ + ++ V IFP + +
Sbjct: 470 NLSEIHPWHLHGHDFWVLGYGDGKFTAEEESSLNLKNPPLRNTVV--IFPYGWTAIRFVA 527
Query: 1031 RTPGIWLLHCHVTDHIHAGMETTY 1054
PG+W HCH+ H+H GM +
Sbjct: 528 DNPGVWAFHCHIEPHLHMGMGVVF 551
</PRE>
<PRE>
Score = 42.0 bits (97), Expect = 0.006
Identities = 39/132 (29%), Positives = 55/132 (41%), Gaps = 21/132 (15%)
Query: 92 FLGPIIKAETGDKVYVHLKN-LASRPYTFHSHGITYYKEHEGAIYPDNTTDFQRADDKVY 150
F GP I+A GD V V L N L + H HGI G + D T + +
Sbjct: 61 FPGPTIRANAGDTVVVELINKLHTEGVVIHWHGIL----QRGTPWADGTASISQC--AIN 114
Query: 151 PGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASGLIGPLIICKKDSLDKEKE 210
PGE + Y +PG T YH H+ + ++GL G LI+ K++
Sbjct: 115 PGETFFYNFTV---DNPG-------TFFYHGHLGMQR--SAGLYGSLIVDPPQG--KKEP 160
Query: 211 KHIDREFVVMFS 222
H D E ++ S
Sbjct: 161 FHYDGEINLLLS 172
</PRE>
<PRE>
><a name = 2833234></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02833234&dopt=GenPept" >sp|Q12719|LAC4_TRAVE</a> LACCASE 4 PRECURSOR (BENZENEDIOL:OXYGEN OXIDOREDUCTASE) (URISHIOL
OXIDASE) (DIPHENOL OXIDASE)
Length = 520
Score = 41.6 bits (96), Expect = 0.008
Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 16/80 (20%)
Query: 994 HTVHFHGHSFQYKHRGVYSSDVFDIFP-----------GTYQTLEMFPRTPGIWLLHCHV 1042
H H HGH+F R S+D + P G T+ PG W LHCH+
Sbjct: 418 HPFHLHGHTFSIV-RTAGSTDTNFVNPVRRDVVNTGTAGDNVTIRFTTDNPGPWFLHCHI 476
Query: 1043 TDHIHAGMETTYTVLQNEDT 1062
H+ AG + ++ +EDT
Sbjct: 477 DFHLEAG----FAIVFSEDT 492
</PRE>
<PRE>
><a name = 2842755></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02842755&dopt=GenPept" >sp|Q99055|LAC4_TRAVI</a> LACCASE 4 PRECURSOR (BENZENEDIOL:OXYGEN OXIDOREDUCTASE) (URISHIOL
OXIDASE) (DIPHENOL OXIDASE)
Length = 520
Score = 41.6 bits (96), Expect = 0.008
Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 16/80 (20%)
Query: 994 HTVHFHGHSFQYKHRGVYSSDVFDIFP-----------GTYQTLEMFPRTPGIWLLHCHV 1042
H H HGH+F R S+D + P G T+ PG W LHCH+
Sbjct: 418 HPFHLHGHTFSIV-RTAGSTDTNFVNPVRRDVVNTGTVGDNVTIRFTTDNPGPWFLHCHI 476
Query: 1043 TDHIHAGMETTYTVLQNEDT 1062
H+ AG + ++ +EDT
Sbjct: 477 DFHLEAG----FAIVFSEDT 492
</PRE>
<PRE>
><a name = 2833229></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02833229&dopt=GenPept" >sp|Q12570|LAC1_BOTCI</a> LACCASE (BENZENEDIOL:OXYGEN OXIDOREDUCTASE) (URISHIOL OXIDASE)
(DIPHENOL OXIDASE)
Length = 486
Score = 40.4 bits (93), Expect = 0.017
Identities = 20/71 (28%), Positives = 31/71 (43%), Gaps = 14/71 (19%)
Query: 994 HTVHFHGHSFQYKHRGV--YSS------------DVFDIFPGTYQTLEMFPRTPGIWLLH 1039
H +H HGH F +G Y++ DV + G + + PG WL+H
Sbjct: 370 HPIHLHGHDFWTLSQGTGAYTATTALNLVNPPRRDVLTLSTGGHLVIAFQIDNPGSWLMH 429
Query: 1040 CHVTDHIHAGM 1050
CH+ H+ G+
Sbjct: 430 CHIAWHVSEGL 440
</PRE>
<PRE>
><a name = 2829462></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02829462&dopt=GenPept" >sp|P56193|LAC1_THACU</a> LACCASE 1 PRECURSOR (BENZENEDIOL:OXYGEN OXIDOREDUCTASE) (URISHIOL
OXIDASE) (DIPHENOL OXIDASE)
Length = 576
Score = 40.0 bits (92), Expect = 0.023
Identities = 62/288 (21%), Positives = 113/288 (38%), Gaps = 52/288 (18%)
Query: 91 GFLGPIIKAETGDKVYVHLKNLASRPYTF-----HSHGITYYKEHEGAIYPDNTTDFQRA 145
G+ GP+I A GD + V ++N + P + H HG+ ++ + D+ F
Sbjct: 48 GYPGPLIFANKGDTLKVKVQNKLTNPEMYRTTSIHWHGLLQHRNAD-----DDGPSFV-T 101
Query: 146 DDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASGLIGPLIICKKDSL 205
+ P E YTY + ++ T YHSH+ + GL GPL+I D
Sbjct: 102 QCPIVPRESYTYTIPLDDQTG---------TYWYHSHLSS--QYVDGLRGPLVI--YDPK 148
Query: 206 DKEKEKH-IDREFVVMFSVVDENFSWYLEDN--------------IKTYCSEPEKVDKDN 250
D + + +D E V+ ++ + WY E + + + + D DN
Sbjct: 149 DPHRRLYDVDDEKTVL--IIGD---WYHESSKAILASGNITRQRPVSATINGKGRFDPDN 203
Query: 251 EDFQESNRMYSVNGYTFGSLPGLSMCAEDRVKWYLFGM-GNEVDVHAAFFHGQALTNKNY 309
+ +Y++ G L + + + F + G++V V AA ++ K Y
Sbjct: 204 TP-ANPDTLYTLK-VKRGKRYRLRVINSSEIASFRFSVEGHKVTVIAA----DGVSTKPY 257
Query: 310 RIDTINLFPATLFDAYMVA-QNPGEWMLSCQNLNHLKAGLQAFFQVQE 356
++D ++ D + A Q P + ++ N QA +E
Sbjct: 258 QVDAFDILAGQRIDCVVEANQEPDTYWINAPLTNVPNKTAQALLVYEE 305
</PRE>
<PRE>
Score = 38.1 bits (87), Expect = 0.086
Identities = 33/118 (27%), Positives = 51/118 (42%), Gaps = 25/118 (21%)
Query: 796 VERKAEEEHLGILGPQLHADVGDKVKIIFKNMATRP-----YSIHAHGVQTESS------ 844
V+R A + G GP + A+ GD +K+ +N T P SIH HG+ +
Sbjct: 38 VKRNATLVNGGYPGPLIFANKGDTLKVKVQNKLTNPEMYRTTSIHWHGLLQHRNADDDGP 97
Query: 845 ---TVTPTLPGETLTYVWKIPERSGAGTEDSACIPWAYYSTVDQVKDLYSGLIGPLIV 899
T P +P E+ TY + +++G W + Q D GL GPL++
Sbjct: 98 SFVTQCPIVPRESYTYTIPLDDQTGT--------YWYHSHLSSQYVD---GLRGPLVI 144
</PRE>
<PRE>
><a name = 2833189></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02833189&dopt=GenPept" >sp|Q02075|LAC2_THACU</a> LACCASE 2 PRECURSOR (BENZENEDIOL:OXYGEN OXIDOREDUCTASE) (URISHIOL
OXIDASE) (DIPHENOL OXIDASE)
Length = 599
Score = 40.0 bits (92), Expect = 0.023
Identities = 32/115 (27%), Positives = 49/115 (41%), Gaps = 26/115 (22%)
Query: 92 FLGPIIKAETGDKVYVHLKNLASRP-----YTFHSHGITYYK--EHEGAIYPDNTTDFQR 144
F GP+I A GD + + ++N S P T H HG+ ++ E +G +
Sbjct: 49 FPGPLITANKGDTLKITVRNKLSDPTMRRSTTIHWHGLLQHRTAEEDGPAFVTQC----- 103
Query: 145 ADDKVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASGLIGPLII 199
+ P E YTY + E+ T YHSH+ + GL GP++I
Sbjct: 104 ---PIPPQESYTYTMPLGEQTG---------TYWYHSHLSS--QYVDGLRGPIVI 144
</PRE>
<PRE>
Score = 38.1 bits (87), Expect = 0.086
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 8/80 (10%)
Query: 993 LHTVHFHGHSFQYKHRGVYSSDVF-----DIFPGTYQTLEMFPRT--PGIWLLHCHVTDH 1045
+H +H HGH+F G + + D+ T + + RT PG W LHCH+ H
Sbjct: 496 VHPLHLHGHAFDVVQFGDNAPNYVNPPRRDVVGVTDAGVRIQFRTDNPGPWFLHCHIDWH 555
Query: 1046 IHAGMETTYTVLQNEDTKSG 1065
+ G + ED K G
Sbjct: 556 LEEGFAMVFAEAP-EDIKKG 574
</PRE>
<PRE>
><a name = 400156></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=00400156&dopt=GenPept" >sp|Q01679|LAC1_PHLRA</a> Laccase precursor (Benzenediol:oxygen oxidoreductase) (Urishiol
oxidase) (Ligninolytic phenoloxidase)
Length = 548
Score = 39.3 bits (90), Expect = 0.039
Identities = 21/67 (31%), Positives = 27/67 (39%), Gaps = 10/67 (14%)
Query: 994 HTVHFHGHSFQ---------YKHRGVYSSDVFDIF-PGTYQTLEMFPRTPGIWLLHCHVT 1043
H H HGH+F Y + DV I G T+ PG W LHCH+
Sbjct: 418 HPFHLHGHTFSVVRPAGSTTYNYVNPVQRDVVSIGNTGDNVTIRFDTNNPGPWFLHCHID 477
Query: 1044 DHIHAGM 1050
H+ A +
Sbjct: 478 WHLEAAL 484
</PRE>
<PRE>
><a name = 2833199></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02833199&dopt=GenPept" >sp|Q03966|LAC1_CRYPA</a> LACCASE PRECURSOR (BENZENEDIOL:OXYGEN OXIDOREDUCTASE) (URISHIOL
OXIDASE)
Length = 591
Score = 38.9 bits (89), Expect = 0.050
Identities = 22/86 (25%), Positives = 31/86 (35%), Gaps = 25/86 (29%)
Query: 994 HTVHFHGHSFQYKHRGVYSS-------------------------DVFDIFPGTYQTLEM 1028
H +H HGH F R S DV + P + +
Sbjct: 463 HPIHLHGHDFVVLGRSPNVSPTAQTPYTFTSSDVSSLNGNNPIRRDVVMLPPKGWLLIAF 522
Query: 1029 FPRTPGIWLLHCHVTDHIHAGMETTY 1054
PG WL+HCH+ H+ AG+ T+
Sbjct: 523 QTTNPGAWLMHCHIAWHVSAGLGNTF 548
</PRE>
<PRE>
><a name = 2493323></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02493323&dopt=GenPept" >sp|P78591|FET3_CANAL</a> IRON TRANSPORT MULTICOPPER OXIDASE PRECURSOR
Length = 624
Score = 38.9 bits (89), Expect = 0.050
Identities = 25/106 (23%), Positives = 38/106 (35%), Gaps = 32/106 (30%)
Query: 977 GDEVNWYLMGMGNEIDL---------HTVHFHGHSFQY--KHRGVYSS------------ 1013
G N +++ G+ +D+ H H HGH FQ +H + S
Sbjct: 387 GTNTNSFVLQGGDIVDIVLNNFDTGKHPFHLHGHVFQLIERHEAIGSKESAVTFNVSDHA 446
Query: 1014 ---------DVFDIFPGTYQTLEMFPRTPGIWLLHCHVTDHIHAGM 1050
D + P +Y L P +W HCHV H+ G+
Sbjct: 447 EWPEYPMIRDTVYVKPHSYMVLRFKADNPVVWFFHCHVDWHLEQGL 492
</PRE>
<PRE>
><a name = 18281739></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=18281739&dopt=GenPept" >sp|Q99056|LAC5_TRAVI</a> Laccase 5 precursor (Benzenediol:oxygen oxidoreductase) (Urishiol
oxidase)
Length = 527
Score = 38.9 bits (89), Expect = 0.050
Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 14/79 (17%)
Query: 994 HTVHFHGHSFQYKHRG----------VYSSDVFDIFPGTYQTLEMFPRTPGIWLLHCHVT 1043
H H HGH+F V V G T+ PG W LHCH+
Sbjct: 425 HPFHLHGHTFSVVRSAGSSTFNYANPVRRDTVSTGNSGDNVTIRFTTDNPGPWFLHCHID 484
Query: 1044 DHIHAGMETTYTVLQNEDT 1062
H+ AG + ++ EDT
Sbjct: 485 FHLEAG----FAIVWGEDT 499
</PRE>
<PRE>
><a name = 2842752></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02842752&dopt=GenPept" >sp|Q99044|LAC1_TRAVI</a> LACCASE 1 PRECURSOR (BENZENEDIOL:OXYGEN OXIDOREDUCTASE) (URISHIOL
OXIDASE) (DIPHENOL OXIDASE)
Length = 520
Score = 38.1 bits (87), Expect = 0.086
Identities = 23/73 (31%), Positives = 31/73 (41%), Gaps = 12/73 (16%)
Query: 994 HTVHFHGHSFQYKHRG---VYSSD--VF-DIFP------GTYQTLEMFPRTPGIWLLHCH 1041
H H HGH+F VY+ D +F D+ G T+ PG W LHCH
Sbjct: 416 HPFHLHGHAFAVVRSAGSTVYNYDNPIFRDVVSTGTPAAGDNVTIRFRTDNPGPWFLHCH 475
Query: 1042 VTDHIHAGMETTY 1054
+ H+ AG +
Sbjct: 476 IDFHLEAGFAVVF 488
</PRE>
<PRE>
><a name = 1730082></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=01730082&dopt=GenPept" >sp|Q02497|LAC1_CORHI</a> Laccase precursor (Benzenediol:oxygen oxidoreductase) (Urishiol
oxidase) (Ligninolytic phenoloxidase)
Length = 520
Score = 38.1 bits (87), Expect = 0.086
Identities = 23/73 (31%), Positives = 31/73 (41%), Gaps = 12/73 (16%)
Query: 994 HTVHFHGHSFQYKHRG---VYSSD--VF-DIFP------GTYQTLEMFPRTPGIWLLHCH 1041
H H HGH+F VY+ D +F D+ G T+ PG W LHCH
Sbjct: 416 HPFHLHGHAFAVVRSAGSTVYNYDNPIFRDVVSTGTPAAGDNVTIRFRTDNPGPWFLHCH 475
Query: 1042 VTDHIHAGMETTY 1054
+ H+ AG +
Sbjct: 476 IDFHLEAGFAVVF 488
</PRE>
<PRE>
><a name = 2842753></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02842753&dopt=GenPept" >sp|Q99046|LAC2_TRAVI</a> LACCASE 2 PRECURSOR (BENZENEDIOL:OXYGEN OXIDOREDUCTASE) (URISHIOL
OXIDASE) (DIPHENOL OXIDASE)
Length = 519
Score = 37.7 bits (86), Expect = 0.11
Identities = 21/73 (28%), Positives = 27/73 (36%), Gaps = 12/73 (16%)
Query: 994 HTVHFHGHSFQ---------YKHRGVYSSDVFDI---FPGTYQTLEMFPRTPGIWLLHCH 1041
H H HGH+F Y + DV G T+ PG W LHCH
Sbjct: 415 HPFHLHGHAFAVVRSAGSTTYNYNDPIFRDVVSTGTPAAGDNVTIRFQTDNPGPWFLHCH 474
Query: 1042 VTDHIHAGMETTY 1054
+ H+ AG +
Sbjct: 475 IDFHLDAGFAIVF 487
</PRE>
<PRE>
><a name = 1175947></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=01175947&dopt=GenPept" >sp|P43561|FET5_YEAST</a> Iron transport multicopper oxidase FET5 precursor
Length = 622
Score = 37.7 bits (86), Expect = 0.11
Identities = 26/120 (21%), Positives = 42/120 (34%), Gaps = 42/120 (35%)
Query: 977 GDEVNWYLMGMGNEIDL---------HTVHFHGHSFQ--YKHRGVYSSDVFD-------- 1017
GD +N L+ + I++ H H HGH+FQ K G + + +D
Sbjct: 392 GDNINAQLLKHNDIIEVVLNNYDSGRHPFHLHGHNFQIVQKSPGFHVDEAYDESEQDEMT 451
Query: 1018 -----------------------IFPGTYQTLEMFPRTPGIWLLHCHVTDHIHAGMETTY 1054
+ P + L PG+W HCHV H+ G+ + +
Sbjct: 452 VPYNESAPLQPFPERPMVRDTVVLEPSGHVVLRFRADNPGVWYFHCHVDWHLQQGLASVF 511
</PRE>
<PRE>
Score = 35.4 bits (80), Expect = 0.56
Identities = 26/99 (26%), Positives = 42/99 (42%), Gaps = 19/99 (19%)
Query: 787 YTDSTFRVPVERKAEEEHLGILG----PQLHADVGDKVKIIFKN--MATRPYSIHAHGVQ 840
YT S + E+ +G G P +H + GD+V++ N S+H HG+
Sbjct: 25 YTASWVTANPDGLHEKRMIGFNGEWPLPDIHVEKGDRVELYLTNGFQDNTATSLHFHGLF 84
Query: 841 TESS-------------TVTPTLPGETLTYVWKIPERSG 866
+S T P +PG+T Y + +PE+ G
Sbjct: 85 QNTSLGNQLQMDGPSMVTQCPIVPGQTYLYNFTVPEQVG 123
</PRE>
<PRE>
><a name = 2833233></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02833233&dopt=GenPept" >sp|Q12718|LAC2_TRAVE</a> Laccase 2 precursor (Benzenediol:oxygen oxidoreductase) (Urishiol
oxidase) (Diphenol oxidase) (Laccase I)
Length = 519
Score = 37.7 bits (86), Expect = 0.11
Identities = 21/73 (28%), Positives = 27/73 (36%), Gaps = 12/73 (16%)
Query: 994 HTVHFHGHSFQ---------YKHRGVYSSDVFDI---FPGTYQTLEMFPRTPGIWLLHCH 1041
H H HGH+F Y + DV G T+ PG W LHCH
Sbjct: 415 HPFHLHGHAFAVVRSAGSTTYNYNDPIFRDVVSTGTPAAGDNVTIRFQTDNPGPWFLHCH 474
Query: 1042 VTDHIHAGMETTY 1054
+ H+ AG +
Sbjct: 475 IDFHLDAGFAIVF 487
</PRE>
<PRE>
><a name = 2833190></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02833190&dopt=GenPept" >sp|Q02079|LAC3_THACU</a> LACCASE 3 PRECURSOR (BENZENEDIOL:OXYGEN OXIDOREDUCTASE) (URISHIOL
OXIDASE) (DIPHENOL OXIDASE)
Length = 572
Score = 37.4 bits (85), Expect = 0.15
Identities = 33/118 (27%), Positives = 50/118 (41%), Gaps = 25/118 (21%)
Query: 796 VERKAEEEHLGILGPQLHADVGDKVKIIFKNMATRP-----YSIHAHGVQTESS------ 844
VER A + G GP + A+ GD +K+ +N T P SIH HG+ +
Sbjct: 38 VERDATLVNGGYPGPLIFANKGDTLKVKVQNKLTNPDMYRTTSIHWHGLLQHRNADDDGP 97
Query: 845 ---TVTPTLPGETLTYVWKIPERSGAGTEDSACIPWAYYSTVDQVKDLYSGLIGPLIV 899
T P +P + TY + +++G W + Q D GL GPL++
Sbjct: 98 AFVTQCPIVPQASYTYTMPLGDQTGT--------YWYHSHLSSQYVD---GLRGPLVI 144
</PRE>
<PRE>
Score = 37.0 bits (84), Expect = 0.19
Identities = 19/69 (27%), Positives = 30/69 (42%), Gaps = 7/69 (10%)
Query: 993 LHTVHFHGHSFQYKHRGVYSSDVF-----DIFPGTYQTLEMFPRT--PGIWLLHCHVTDH 1045
+H +H HGH+F G + D+ T + + +T PG W LHCH+ H
Sbjct: 469 VHPIHLHGHTFDVVQFGNNPPNYVNPPRRDVVGATDEGVRFQFKTDNPGPWFLHCHIDWH 528
Query: 1046 IHAGMETTY 1054
+ G +
Sbjct: 529 LEEGFAMVF 537
</PRE>
<PRE>
Score = 36.2 bits (82), Expect = 0.33
Identities = 30/112 (26%), Positives = 48/112 (42%), Gaps = 18/112 (16%)
Query: 91 GFLGPIIKAETGDKVYVHLKNLASRPYTFHSHGITYYKEHEGAIYPDNTTDFQRA---DD 147
G+ GP+I A GD + V ++N + P + + I ++ G + N D A
Sbjct: 48 GYPGPLIFANKGDTLKVKVQNKLTNPDMYRTTSIHWH----GLLQHRNADDDGPAFVTQC 103
Query: 148 KVYPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASGLIGPLII 199
+ P YTY + ++ T YHSH+ + GL GPL+I
Sbjct: 104 PIVPQASYTYTMPLGDQTG---------TYWYHSHLSS--QYVDGLRGPLVI 144
</PRE>
<PRE>
><a name = 2833237></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02833237&dopt=GenPept" >sp|Q12739|LAC2_PLEOS</a> LACCASE 2 PRECURSOR (BENZENEDIOL:OXYGEN OXIDOREDUCTASE) (URISHIOL
OXIDASE) (DIPHENOL OXIDASE)
Length = 533
Score = 37.4 bits (85), Expect = 0.15
Identities = 20/72 (27%), Positives = 27/72 (36%), Gaps = 11/72 (15%)
Query: 994 HTVHFHGHSFQ---------YKHRGVYSSDVFDIFPGTYQ--TLEMFPRTPGIWLLHCHV 1042
H H HGH+F Y DV + G T+ PG W LHCH+
Sbjct: 427 HPFHLHGHTFDVIRSAGSTTYNFDTPARRDVVNTGTGANDNVTIRFVTDNPGPWFLHCHI 486
Query: 1043 TDHIHAGMETTY 1054
H+ G+ +
Sbjct: 487 DWHLEIGLAVVF 498
</PRE>
<PRE>
><a name = 2833232></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02833232&dopt=GenPept" >sp|Q12717|LAC5_TRAVE</a> LACCASE 5 PRECURSOR (BENZENEDIOL:OXYGEN OXIDOREDUCTASE) (URISHIOL
OXIDASE) (DIPHENOL OXIDASE) (LACCASE IV)
Length = 527
Score = 37.4 bits (85), Expect = 0.15
Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 14/79 (17%)
Query: 994 HTVHFHGHSFQYKHRG----------VYSSDVFDIFPGTYQTLEMFPRTPGIWLLHCHVT 1043
H H HGH+F V V G T+ PG W LHCH+
Sbjct: 425 HPFHLHGHTFSVVRSAGSSTFNYANPVRRDTVSTGNSGDNVTIRFTTDNPGPWFLHCHID 484
Query: 1044 DHIHAGMETTYTVLQNEDT 1062
H+ AG + ++ EDT
Sbjct: 485 FHLDAG----FAIVFAEDT 499
</PRE>
<PRE>
><a name = 2833235></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02833235&dopt=GenPept" >sp|Q12729|LAC1_PLEOS</a> LACCASE 1 PRECURSOR (BENZENEDIOL:OXYGEN OXIDOREDUCTASE) (URISHIOL
OXIDASE) (DIPHENOL OXIDASE)
Length = 529
Score = 37.0 bits (84), Expect = 0.19
Identities = 20/72 (27%), Positives = 29/72 (39%), Gaps = 11/72 (15%)
Query: 994 HTVHFHGHSFQYKHRGVYSSDVFD-------IFPGTYQ----TLEMFPRTPGIWLLHCHV 1042
H H HGH+F ++ FD + GT T+ PG W LHCH+
Sbjct: 425 HPFHLHGHTFDVIRSAGSTTYNFDTPARRDVVNTGTDANDNVTIRFVTDNPGPWFLHCHI 484
Query: 1043 TDHIHAGMETTY 1054
H+ G+ +
Sbjct: 485 DWHLEIGLAVVF 496
</PRE>
<PRE>
><a name = 2833200></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02833200&dopt=GenPept" >sp|Q04399|YD56_YEAST</a> PUTATIVE MULTICOPPER OXIDASE YDR506C
Length = 608
Score = 37.0 bits (84), Expect = 0.19
Identities = 31/132 (23%), Positives = 45/132 (33%), Gaps = 33/132 (25%)
Query: 958 MHAINGRMFGNLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQY-----KHRGVYS 1012
M+ +N R F + G + ++ + H H HGH FQ K G +
Sbjct: 416 MYKVNERTFSEYVKDPVRFGFNETYDIVINSLDHMRHPWHMHGHHFQIISLGNKGDGPFH 475
Query: 1013 SDV----------------------------FDIFPGTYQTLEMFPRTPGIWLLHCHVTD 1044
DV +I +Y L + PG WLLHCHV
Sbjct: 476 KDVQEGKAWSRYQNDLRHLARTGKAPMVRDSINIAGNSYAVLRINTEMPGKWLLHCHVEW 535
Query: 1045 HIHAGMETTYTV 1056
H+ G+ + V
Sbjct: 536 HMMKGLGIVFEV 547
</PRE>
<PRE>
><a name = 2828219></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02828219&dopt=GenPept" >sp|P38993|FET3_YEAST</a> Iron transport multicopper oxidase FET3 precursor
Length = 636
Score = 36.6 bits (83), Expect = 0.25
Identities = 22/82 (26%), Positives = 31/82 (36%), Gaps = 25/82 (30%)
Query: 994 HTVHFHGHSFQYKHRGVYSSDV---------------FDIFPGTYQTLEMFPRT------ 1032
H H HGH+FQ R D F +P TL + P++
Sbjct: 413 HPFHLHGHAFQTIQRDRTYDDALGEVPHSFDPDNHPAFPEYPMRRDTLYVRPQSNFVIRF 472
Query: 1033 ----PGIWLLHCHVTDHIHAGM 1050
PG+W HCH+ H+ G+
Sbjct: 473 KADNPGVWFFHCHIEWHLLQGL 494
</PRE>
<PRE>
><a name = 2827765></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=02827765&dopt=GenPept" >sp|P25006|NIR_ACHCY</a> COPPER-CONTAINING NITRITE REDUCTASE PRECURSOR (CU-NIR)
Length = 378
Score = 35.8 bits (81), Expect = 0.43
Identities = 30/116 (25%), Positives = 48/116 (40%), Gaps = 13/116 (11%)
Query: 954 ESNKMHAI--NGRMFGNLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRGVY 1011
E ++HA+ NG + G L + +H D V L+ LH + FH + +
Sbjct: 93 EGTEIHAMTFNGSVPGPL--MVVHENDYVELRLINPDTNTLLHNIDFHAAT-----GALG 145
Query: 1012 SSDVFDIFPGTYQTLEMFPRTPGIWLLHC----HVTDHIHAGMETTYTVLQNEDTK 1063
+ + PG TL PG+++ HC V H+ +GM VL + K
Sbjct: 146 GGALTQVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLK 201
</PRE>
<PRE>
><a name = 13632794></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=13632794&dopt=GenPept" >sp|Q47452|PCOA_ECOLI</a> Copper resistance protein A precursor
Length = 605
Score = 35.8 bits (81), Expect = 0.43
Identities = 21/94 (22%), Positives = 39/94 (41%), Gaps = 5/94 (5%)
Query: 960 AINGRMFGNLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRG---VYSSDVF 1016
+ NG F + + + G+ + L+ + + H +H HG + +
Sbjct: 506 SFNGIKFSDAAPVLLKYGERLRITLIN--DTMMTHPIHLHGMWSDLEDENGNFMVRKHTI 563
Query: 1017 DIFPGTYQTLEMFPRTPGIWLLHCHVTDHIHAGM 1050
D+ PGT ++ + G W HCH+ H+ GM
Sbjct: 564 DVPPGTKRSYRVTADALGRWAYHCHLLYHMEMGM 597
</PRE>
<PRE>
Score = 34.7 bits (78), Expect = 0.95
Identities = 49/195 (25%), Positives = 72/195 (36%), Gaps = 39/195 (20%)
Query: 91 GFLGPIIKAETGDKVYVHLKNLASRPYTFHSHGITYYKEHEGAIYPDNTTDFQRADDK-V 149
G GP+++ + GD + + +KN + + H HGI I P N +
Sbjct: 71 GLPGPVLRWKEGDTITLKVKNRLNEQTSIHWHGI---------ILPANMDGVPGLSFMGI 121
Query: 150 YPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASGLIGPLIICKKDSLDKEK 209
P + Y Y + T YHSH + G+ G +II D+ + E
Sbjct: 122 EPDDTYVYTFKVKQNG----------TYWYHSHSGLQEQ--EGVYGAIII---DAREPEP 166
Query: 210 EKHIDREFVVMFS-VVDENFSWYLEDNIKTYCSEPEKVDKDNEDFQESNRMYSVNGYTFG 268
+ DRE VVM S DEN L K K D+ N+ + +
Sbjct: 167 FAY-DREHVVMLSDWTDENPHSLL------------KKLKKQSDYYNFNKPTVGSFFRDV 213
Query: 269 SLPGLSMCAEDRVKW 283
+ GLS DR W
Sbjct: 214 NTRGLSATIADRKMW 228
</PRE>
<PRE>
><a name = 20137839></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=20137839&dopt=GenPept" >sp|Q8ZRS2|CUEO_SALTY</a> Blue copper oxidase cueO precursor (Copper efflux oxidase)
Length = 536
Score = 35.4 bits (80), Expect = 0.56
Identities = 29/109 (26%), Positives = 44/109 (39%), Gaps = 15/109 (13%)
Query: 961 INGRMFG-NLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQY---------KHRGV 1010
ING++F N G W + G+G+ + LH H HG F+ HR
Sbjct: 430 INGQVFDMNKPMFAAQKGRHERWVISGVGDMM-LHPFHIHGTQFRILSENGKAPAAHRTG 488
Query: 1011 YSSDVFDIFPGTYQTLEMFPRTPG---IWLLHCHVTDHIHAGMETTYTV 1056
+ D + G + L F ++ HCH+ +H GM +TV
Sbjct: 489 WK-DTVRVEGGISEVLVKFDHDAPKEHAYMAHCHLLEHEDTGMMLGFTV 536
</PRE>
<PRE>
><a name = 20137822></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=20137822&dopt=GenPept" >sp|Q8Z9E1|CUEO_SALTI</a> Blue copper oxidase cueO precursor (Copper efflux oxidase)
Length = 536
Score = 35.4 bits (80), Expect = 0.56
Identities = 29/109 (26%), Positives = 44/109 (39%), Gaps = 15/109 (13%)
Query: 961 INGRMFG-NLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQY---------KHRGV 1010
ING++F N G W + G+G+ + LH H HG F+ HR
Sbjct: 430 INGQVFDMNKPMFAAQKGRHERWVISGVGDMM-LHPFHIHGTQFRILSENGKAPAAHRTG 488
Query: 1011 YSSDVFDIFPGTYQTLEMFPRTPG---IWLLHCHVTDHIHAGMETTYTV 1056
+ D + G + L F ++ HCH+ +H GM +TV
Sbjct: 489 WK-DTVRVEGGISEVLVKFDHDAPKEHAYMAHCHLLEHEDTGMMLGFTV 536
</PRE>
<PRE>
><a name = 116921></a><a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=Protein&list_uids=00116921&dopt=GenPept" >sp|P12374|COPA_PSESM</a> Copper resistance protein A precursor
Length = 609
Score = 35.0 bits (79), Expect = 0.73
Identities = 35/133 (26%), Positives = 54/133 (40%), Gaps = 26/133 (19%)
Query: 91 GFLGPIIKAETGDKVYVHLKNLASRPYTFHSHGITYYKEHEGAIYPDNTTDFQRAD-DKV 149
G GP+++ + GD V + ++N + H HGI I P N +
Sbjct: 71 GLPGPLLRWKEGDTVTLRVRNRLDAATSIHWHGI---------ILPPNMDGVPGLSFAGI 121
Query: 150 YPGEQYTYMLLATEEQSPGEGDGNCVTRIYHSHIDAPKDIASGLIGPLIICKKDSLDKEK 209
PG Y Y + T YHSH + + G+ GPL+I ++ + E
Sbjct: 122 EPGGVYVYQFKVQQNG----------TYWYHSHSGFQEQV--GVYGPLVI---EAKEPEP 166
Query: 210 EKHIDREFVVMFS 222
K+ D E VVM +
Sbjct: 167 FKY-DSEHVVMLT 178
</PRE>
<PRE>
Score = 34.7 bits (78), Expect = 0.95
Identities = 22/94 (23%), Positives = 39/94 (41%), Gaps = 5/94 (5%)
Query: 960 AINGRMFGNLQGLTMHVGDEVNWYLMGMGNEIDLHTVHFHGHSFQYKHRGV---YSSDVF 1016
+ +G F + Q L + G+ V L+ + + H +H HG +
Sbjct: 510 SFDGIKFADAQPLILKYGERVRIVLVN--DTMMTHPIHLHGMWSDLEDEDGNFRVRKHTI 567
Query: 1017 DIFPGTYQTLEMFPRTPGIWLLHCHVTDHIHAGM 1050
D+ PG+ ++ + G W HCH+ H+ GM
Sbjct: 568 DMPPGSKRSYRVTADALGRWAYHCHLLYHMEMGM 601
</PRE>
<PRE>
Database: Non-redundant SwissProt sequences
Posted date: May 24, 2002 7:34 AM
Number of letters in database: 40,014,366
Number of sequences in database: 109,592
Lambda K H
0.318 0.137 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,811,955
Number of Sequences: 109592
Number of extensions: 4582649
Number of successful extensions: 9944
Number of sequences better than 1.0: 41
Number of HSP's better than 1.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 9433
Number of HSP's gapped (non-prelim): 188
length of query: 1065
length of database: 40,014,366
effective HSP length: 118
effective length of query: 947
effective length of database: 27,082,510
effective search space: 25647136970
effective search space used: 25647136970
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 78 (34.7 bits)
</form>
--M9NhX3UHpAaciwkO--