[Biopython-dev] Bio.SeqUtils.MeltingTemp Tm_staluc does not accept sequence object

Peter Cock p.j.a.cock at googlemail.com
Wed Dec 21 07:39:02 EST 2011


On Wed, Dec 21, 2011 at 12:22 PM, Markus Piotrowski
<Markus.Piotrowski at ruhr-uni-bochum.de> wrote:
>
> I'm still worried about whitespaces, which, in this method, would influence the
> calculation by three ways:
> ...
>
> It is of course a more philosophical question if the method should catch these
> problems or if the method can rely on a 'proper' sequence (i.e., without blanks).

I would say it is reasonable for the melting temperature function to assume
sensible sequences as input, and leave validation to the user.

Peter


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