[Biopython-dev] [Bug 2999] SeqIO.parse() or record.format("genbank") converts input sequence to uppercase or

[bugzilla-daemon at portal.open-bio.org]

http://bugzilla.open-bio.org/show_bug.cgi?id=2999





------- Comment #1 from biopython-bugzilla at maubp.freeserve.co.uk  2010-01-26 08:03 EST -------
In many file formats (e.g. FASTA) mixed case is allowed and useful.

The sequence in a GenBank file is (by convention) always lower case,
but for historical reasons Biopython converts this to upper case on
parsing (not sure why, but changing it would risk breaking existing
scripts).

However, I think we should convert to lower case on writing GenBank
output.

Peter


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