ID   ACT2_XENTR     STANDARD;      PRT;   377 AA.
AC   P20399; Q6GSH4;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   25-JUL-2006, entry version 45.
DE   Actin, alpha sarcomeric/cardiac (Actin alpha 2).
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;
OC   Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TISSUE=Sarcomere;
RX   MEDLINE=88004409; PubMed=3653078;
RA   Stutz F., Spohr G.;
RT   "A processed gene coding for a sarcomeric actin in Xenopus laevis and
RT   Xenopus tropicalis.";
RL   EMBO J. 6:1989-1995(1987).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved
CC       in various types of cell motility and are ubiquitously expressed
CC       in all eukaryotic cells.
CC   -!- SUBUNIT: Polymerization of globular actin (G-actin) leads to a
CC       structural filament (F-actin) in the form of a two-stranded helix.
CC       Each actin can bind to 4 others.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- MISCELLANEOUS: In Xenopus, three different alpha actins have been
CC       identified, a single smooth muscle actin and two sarcomeric forms
CC       that are preferentially expressed either in the heart or in the
CC       skeletal muscle. Each of these three alpha actin genes is present
CC       in at least two copies.
CC   -!- SIMILARITY: Belongs to the actin family.
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DR   EMBL; X05393; CAB43617.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; BC064152; AAH64152.1; -; mRNA.
DR   PIR; B29686; B29686.
DR   UniGene; Str.20527; -.
DR   HSSP; P02568; 1IJJ.
DR   SMR; P20399; 6-373.
DR   Ensembl; ENSXETG00000021417; Xenopus tropicalis.
DR   InterPro; IPR004001; Actin.
DR   InterPro; IPR004000; Actin_like.
DR   PANTHER; PTHR11937; Actin_like; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
KW   Acetylation; ATP-binding; Cytoskeleton; Muscle protein;
KW   Nucleotide-binding; Structural protein.
FT   PROPEP        1      2       Removed in mature form.
FT                                /FTId=PRO_0000000824.
FT   CHAIN         3    377       Actin, alpha sarcomeric/cardiac.
FT                                /FTId=PRO_0000000825.
FT   MOD_RES       3      3       N-acetylaspartate (in mature form) (By
FT                                similarity).
SQ   SEQUENCE   377 AA;  42033 MW;  E5C40FF19730CAD2 CRC64;
     MCDDEETTAL VCDNGSGLVK AGFAGDDAPR AVFPSIVGRP RHQGVMVGMG QKDSYVGDEA
     QSKRGILTLK YPIEHGIITN WDDMEKIWHH TFYNELRVAP EEHPTLLTEA PLNPKANREK
     MTQIMFETFN VPAMYVAIQA VLSLYASGRT TGIVLDSGDG VTHNVPIYEG YALPHAIMRL
     DLAGRDLTDY LMKILTERGY SFVTTAEREI VRDIKEKLCY VALDFENEMA TAASSSSLEK
     SYELPDGQVI TIGNERFRCP ETLFQPSFIG MESAGIHETT YNSIMKCDID IRKDLYANNV
     LSGGTTMYPG IADRMQKEIT ALAPSTMKIK IIAPPERKYS VWIGGSILAS LSTFQQMWIT
     KQEYDEAGPS IVHRKCF
//