[Biojava-l] Biojava-l Digest, Vol 131, Issue 3
Peter S
peters337 at yahoo.co.uk
Fri Jan 17 17:50:53 UTC 2014
Thanks, I will give it a try.
Does it mean there is no fast implementation of SW in java that I can use?
Best,
Peter
On Friday, 17 January 2014, 17:45, Khalil El Mazouari <khalil.elmazouari at gmail.com> wrote:
Hi Peter,
give it a try with Levenshtein Distance. You can use StringUtils from apache common lang. it has a getLevenshteinDistance method.
best,
Khalil
On 17 Jan 2014, at 18:37, Peter S <peters337 at yahoo.co.uk> wrote:
Hi Khalil,
>
>
>By short sequence I mean 12-18 nt long. I need to make alignment against the entire transcriptome and detect matches with up to 3 mismatches. This is the reason I need something quite fast but sensitive at the same time.
>
>
>Many thanks,
>Peter
>
>
>
>On Friday, 17 January 2014, 17:26, Khalil El Mazouari <khalil.elmazouari at gmail.com> wrote:
>
>Hi,
>
>what do you mean by short sequences? NT or AA?
>
>Best
>
>Khalil
>
>On 17 Jan 2014, at 18:00, biojava-l-request at lists.open-bio.org wrote:
>
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>> Today's Topics:
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>> 1. Database search with Smith and Waterman (Peter S)
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>> ----------------------------------------------------------------------
>>
>> Message: 1
>> Date: Fri, 17 Jan 2014 13:27:17 +0000 (GMT)
>> From: Peter S <peters337 at yahoo.co.uk>
>> Subject: [Biojava-l] Database search with Smith and Waterman
>>
To: "biojava-l at lists.open-bio.org" <biojava-l at lists.open-bio.org>
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>>
>> Dear All,?
>>
>> I'm looking for an implementation of Smith and Waterman algorithm to use in the Java desktop application I want to develop.?
>>
>> I did find some information on pairwise aligners but what I would ideally want to have is something similar to the SSEARCH package that can perform alignments against a very big databases,
saved locally in a fasta format. Speed is quite important and ideally I would need an output that I can easily parse, identifying mismatch/gap positions etc.
>>
>> Any suggestions if there is any java implementation that would fit the description? I will be working on short sequences so sensitivity is crucial.?
>>
>> Thanks very much for your help,
>> Peter
>>
>>
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>> End of Biojava-l Digest, Vol 131, Issue 3
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