[Biojava-l] problems with the profilehmm demo

[daniel.rohrbach at web.de]

thanks a lot for the support. I had changed the code, if I'd have got access to the CVS.  When you changed the code, I will be very grateful if you can inform me . I need it for a work on a project for the university.

Daniel

> -----Ursprüngliche Nachricht-----
> Von: "Mark Schreiber" <markjschreiber at gmail.com>
> Gesendet: 29.08.07 16:36:38
> An: "daniel.rohrbach at web.de" <daniel.rohrbach at web.de>
> CC: biojava-l at lists.open-bio.org
> Betreff: Re: [Biojava-l] problems with the profilehmm demo


> 
> Just looked at the CVS on line. You are very likely correct.
> 
> There used to be a listener for changes in the Alphabet but this was
> mistakenly removed as it was thought to be redundant. A diff view is
> here (http://code.open-bio.org/cgi/viewcvs.cgi/biojava-live/src/org/biojava/bio/symbol/LinearAlphabetIndex.java.diff?r1=1.12&r2=1.13&cvsroot=biojava)
> 
> I will check it back in tomorrow unless some one beats me to it. A
> JUnit test is also required to make sure this works.
> 
> - Mark
> 
> On 8/29/07, daniel.rohrbach at web.de <daniel.rohrbach at web.de> wrote:
> > Hi all, hi Mark
> >
> > thanks for the fast Answer.
> >
> > I looked at the code and perhaps solved the problem.
> >
> > During initialisation of the ProfileHMM ( bevore method connectModel() is called ) the transWeights are set with SimpleDistributions sd. These sd again are initialized with an empty Alphabet (no symbol). (*)
> >
> > These Distributions keeps an indexer Object which is used during the training process where the exception occurs.
> >
> > because of (*) the number of indexed symbols is 0 (indexer.symbols.length == 0) and the (FiniteAlphabet)indexer.alphaRef.get() has length 0 too.
> > (Indexer is of type LinearAlphabetIndex)
> >
> > When connectModel() is called the Alphabets ( which are the same as indexer.alphaRef ) are filled with some symbols (EmissionState, DotState ...) (**) BUT the indexer.symbols.length will not be changed (***).
> >
> > This causes the following exception:
> > In SimpleDistribution.Trainer.trainImpl is a method called getWeights(). This will return a double list of length indexer.getAlphabet() which is the same of indexer.alphaRef. Because of (**) this will have a length n>0. So that the for loop in this piece of code runs from 0 to n. Here the exception occurs. indexer.symbolForIndex(i) (0<=i<n) cause the error because of (***) indexer.symbols are empty.
> >
> > I think it must be changed the symbols of the indexer Object in the connectModel() method too. But I'm not really sure because I didn't worked with biojava so long.
> >
> > I'm sorry for my bad English but I hope that I could help a little.
> > Many greetings
> > Daniel
> >
> > > -----Ursprüngliche Nachricht-----
> > > Von: "Mark Schreiber" <markjschreiber at gmail.com>
> > > Gesendet: 28.08.07 16:28:23
> > > An: "Daniel Rohrbach" <daniel.rohrbach at web.de>
> > > CC: biojava-l at lists.open-bio.org
> > > Betreff: Re: [Biojava-l] problems with the profilehmm demo
> >
> >
> > >
> > > Hi -
> > >
> > > This is a bug that has been submitted to bugzilla. Strangely it was
> > > not an issue in the pre-releases of biojava.  I was kind of hoping
> > > someone else would fix it but I guess I will have to find time to take
> > > a look.
> > >
> > > - Mark
> > >
> > > On 8/28/07, Daniel Rohrbach <daniel.rohrbach at web.de> wrote:
> > > > Hi all,
> > > >
> > > > i'm trying to run the  "How do I make a ProfileHMM" example but it doesn't want to work.  I copied the code to my program and when I start it I get the following exceptions:
> > > >
> > > > Exception in thread "main" java.lang.IndexOutOfBoundsException: Can't find symbol for index 0
> > > >         at org.biojava.bio.symbol.LinearAlphabetIndex.symbolForIndex(LinearAlphabetIndex.java:106)
> > > >         at org.biojava.bio.dist.SimpleDistribution$Trainer.trainImpl(SimpleDistribution.java:332)
> > > >         at org.biojava.bio.dist.SimpleDistribution$Trainer.train(SimpleDistribution.java:306)
> > > >         at org.biojava.bio.dist.SimpleDistributionTrainerContext.train(SimpleDistributionTrainerContext.java:126)
> > > >         at biojavatests.HMMTest.main(HMMTest.java:71)
> > > >
> > > > The error occurs at mt.train(). It seems that there was no, wrong or empty alphabet set for the trainer that shall be used.
> > > >
> > > > here the link to the examplepage: http://biojava.org/wiki/BioJava:CookBook:DP:HMM
> > > > any help on this topic?
> > > >
> > > > Thanks in advance
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