[Biojava-dev] Alignment algorithms
Mark A Fortner
m.fortner at sbcglobal.net
Sun Oct 3 10:36:57 EDT 2004
I seem to recall that the neobio API already has both
the Smith-Waterman, and Needleman-Wunsch algorithms
implemented. (http://neobio.sf.net)
As for ClustalW, I've seen several wrapper
implementations but no implementation in Java.
Hope this helps,
Mark Fortner
Mgr. Bioinformatics Software Dev
Lexicon Genetics
--- Rahul Karnik <rahul at genebrew.com> wrote:
> While reading through "Biological Sequence
> Analysis", I am finding it
> useful to reimplement some standard alignment
> algorithms in Java.
> Looking through the current Biojava package, I see
> that alignment is
> limited to HMM based methods. Would there be any
> interest in patches
> that add some standard alignment algorithms to the
> Biojava package? The
> ones I had in mind were Smith-Waterman (with
> substitution matrices),
> ClustalW and TCoffee. Along those lines, what would
> the appropriate
> package to use for such classes? And where should
> the substitution
> matrices go?
>
> Thanks,
> Rahul
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