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<p><font size=3 face="Times New Roman"><span style='font-size:12.0pt'>Hello,</span></font></p>
<p><font size=3 face="Times New Roman"><span style='font-size:12.0pt'>Is there
an EMBOSS equivalent of GCG:FrameAlign?</span></font></p>
<p><font size=3 face="Times New Roman"><span style='font-size:12.0pt'>It
creates an optimal alignment of the best segment of similarity (local
alignment) between a protein sequence and the codons in all possible reading
frames on a single strand of a nucleotide sequence. Optimal alignments may
include reading frame shifts. </span></font></p>
<p><font size=3 face="Times New Roman"><span style='font-size:12.0pt'>This is a
very crucial tool for the evolutionary biologists.</span></font></p>
<p><font size=3 face="Times New Roman"><span style='font-size:12.0pt'>-thanks</span></font></p>
<p><font size=3 face="Times New Roman"><span style='font-size:12.0pt'>-laxman</span></font></p>
<p class=MsoNormal><b><font size=3 color=black face="Times New Roman"><span
style='font-size:12.0pt;color:black;font-weight:bold'> </span></font></b></p>
<p class=MsoNormal><font size=3 color=black face="Times New Roman"><span
style='font-size:12.0pt;color:black'> </span></font></p>
<p class=MsoNormal><font size=2 color=black face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:black'>Lakshmanan Iyer</span></font><font
size=2 color=black face=Arial><span style='font-size:10.0pt;font-family:Arial;
color:black'>, Ph. D.</span></font></p>
<p class=MsoNormal><font size=2 color=black face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:black'>Computational Biologist</span></font></p>
<p class=MsoNormal><font size=2 color=black face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:black'>Manager of Collaboration and Training</span></font></p>
<p class=MsoNormal><font size=2 color=black face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:black'>Computational Biology Group</span></font></p>
<p class=MsoNormal><font size=2 color=black face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:black'>Bauer</span></font><font size=2
color=black face=Arial><span style='font-size:10.0pt;font-family:Arial;
color:black'> </span></font><font size=2 color=black face=Arial><span
style='font-size:10.0pt;font-family:Arial;color:black'>Center</span></font><font
size=2 color=black face=Arial><span style='font-size:10.0pt;font-family:Arial;
color:black'> for Genomics Research</span></font></p>
<p class=MsoNormal><font size=2 color=black face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:black'>Bauer Laboratory</span></font></p>
<p class=MsoNormal><font size=2 color=black face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:black'>7 Divinity Ave.</span></font></p>
<p class=MsoNormal><font size=2 color=black face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:black'>Cambridge</span></font><font size=2
color=black face=Arial><span style='font-size:10.0pt;font-family:Arial;
color:black'>, </span></font><font size=2 color=black face=Arial><span
style='font-size:10.0pt;font-family:Arial;color:black'>MA</span></font><font
size=2 color=black face=Arial><span style='font-size:10.0pt;font-family:Arial;
color:black'> </span></font><font size=2 color=black face=Arial><span
style='font-size:10.0pt;font-family:Arial;color:black'>02138</span></font></p>
<p class=MsoNormal><font size=2 color=black face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:black'><a href="http://www.cgr.harvard.edu">www.cgr.harvard.edu</a></span></font></p>
<p class=MsoNormal><font size=2 color=black face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:black'>Phone:617-384-7647</span></font></p>
<p class=MsoNormal><font size=2 color=black face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:black'>Fax: 617-495-2196</span></font></p>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'> </span></font></p>
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