[Biopython] alignment scores -fitting to Poisson distribution

George Devaniranjan devaniranjan at gmail.com
Wed Nov 16 20:39:28 UTC 2011


Hello,

I did an alignment of a protein with hundreds of other proteins--I got
a distribution that is NOT normal (see attached picture).
I was wondering if biopython had a way of fitting this to one of the
distribution  methods?
I don't have mathlab/maple software, so if biopython cannot do it but
if someone knows of an alternate software that I can use to fit this
data--I would appreciate the help.

What I want is to say......the target PDB was 'X' sigma away from the
mean of the distribution.
If it was a normal distribution, it would be easy to do, since the
distribution is skewed I am wondering the best way to do it.

Thank you,
George
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