[Biopython] comparing micro array data

Sean Davis sdavis2 at mail.nih.gov
Tue Mar 16 16:38:31 UTC 2010


On Tue, Mar 16, 2010 at 11:03 AM, Vincent Davis
<vincent at vincentdavis.net> wrote:
> So I am very new to this so please accept my ignorance on this subject.
>
> I have several micro array samples ~ 8 for each of 3 known genomes. So I
> know which probes/sequences are a match and which have close matches. I
> would like to identify which sequences exist in an unknown sample. The array
> is custom and there is little to know overlap between probes.
> What is the "standard" way of doing this? I don't care to know if a SNP is
> present only if the sequence is present.
> Is this standard available in biopython ?

Hi, Vincent.  I'm not clear on what the study is here.  Could you
explain a bit more what you are doing?  I get the suggestion from your
email that you want to do a cross-species comparison using
microarrays.  If this is the case, this is notoriously difficult to
do, so, in addition to the comments here, I would suggest finding a
local collaborator if you are relatively new to the microarray field.

Sean



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