[BioPython] EST Alignment

Sean Davis sdavis2 at mail.nih.gov
Thu May 29 11:33:42 UTC 2008


On Thu, May 29, 2008 at 6:18 AM, Ann Loraine <aloraine at gmail.com> wrote:
> Have you looked at blat?

Or GMAP (or many others)?

> On Wed, May 28, 2008 at 10:16 PM, Michael Fahy <fahy at chapman.edu> wrote:
>> I expect to be getting two sets of ESTs from two stages of an organism whose genome has been sequenced.  I would like to align the ESTs to the genome sequence to identify the genes that are being expressed and, more importantly, to find the differences in genes between the two sets.  There is an EST2GENOME class in BioPerl that looks like it would help. Is there anything similar in BioPython?  Or public tools, accessible thorugh BioPython,  for identifying genes by aligning ESTs to genome sequences?
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