Stefanie Lück wrote: > Thanks for all the reply! > Could someone tell me also how I can change the paramters over Biopyton? I > this possible? > > Stefanie You should be able to invoke any of the Blast options via Biopython. from Bio.Blast.NCBIStandalone import blastall help(blastall) from Bio.Blast.NCBIWWW import qblast help(qblast) Peter