Hi, may I use Bioperl to browse the PubMed database ? What I would do is to run a perl script, give it the keywords and retrieves all the article related without accessing to the NCBI PubMed site. Is it possible ? Thanks, Giuseppe Torelli Bioinformatic Programmer Laboratory of Molecular Evolution Stazione Zoologica A. Dohrn Villa Comunale 80100 Naples - Italy Tel. 0039 81 5833311