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I suffered a HDD failure recently so it may have shuffled off this mortal coil. - Mark Rahul Karnik Sent by: biojava-dev-bounces@portal.open-bio.org 10/03/2004 09:41 AM To: biojava-dev@biojava.org cc: (bcc: Mark Schreiber/GP/Novartis) Subject: [Biojava-dev] Alignment algorithms While reading through "Biological Sequence Analysis", I am finding it useful to reimplement some standard alignment algorithms in Java. Looking through the current Biojava package, I see that alignment is limited to HMM based methods. Would there be any interest in patches that add some standard alignment algorithms to the Biojava package? The ones I had in mind were Smith-Waterman (with substitution matrices), ClustalW and TCoffee. Along those lines, what would the appropriate package to use for such classes? And where should the substitution matrices go? Thanks, Rahul _______________________________________________ biojava-dev mailing list biojava-dev@biojava.org http://biojava.org/mailman/listinfo/biojava-dev From mark.schreiber at group.novartis.com Sun Oct 3 21:41:09 2004 From: mark.schreiber at group.novartis.com (mark.schreiber@group.novartis.com) Date: Sun Oct 3 21:46:41 2004 Subject: [Biojava-dev] Alignment algorithms Message-ID: Nope, looks like its gone to the big Hard Drive in the Sky. I could recode it if there is interest. - Mark Mark Schreiber/GP/Novartis@PH Sent by: biojava-dev-bounces@portal.open-bio.org 10/04/2004 09:34 AM To: Rahul Karnik cc: biojava-dev@biojava.org, biojava-dev-bounces@portal.open-bio.org, (bcc: Mark Schreiber/GP/Novartis) Subject: Re: [Biojava-dev] Alignment algorithms Hi - I did some work on implementing SW and NW in biojava. It works pretty well. The only sticking point you will have is the substitution matrices. Some give scores for ambiguities which you need to be careful of. Ambiguities in Biojava are not atomic symbols but the substitution matrices treat them as if they are. It may actually be more realistic to just average the vaules of whatever the ambiguity is composed of. Hopefully I can dig up the old code which I can submit as a basis. No promises. I suffered a HDD failure recently so it may have shuffled off this mortal coil. - Mark Rahul Karnik Sent by: biojava-dev-bounces@portal.open-bio.org 10/03/2004 09:41 AM To: biojava-dev@biojava.org cc: (bcc: Mark Schreiber/GP/Novartis) Subject: [Biojava-dev] Alignment algorithms While reading through "Biological Sequence Analysis", I am finding it useful to reimplement some standard alignment algorithms in Java. Looking through the current Biojava package, I see that alignment is limited to HMM based methods. Would there be any interest in patches that add some standard alignment algorithms to the Biojava package? The ones I had in mind were Smith-Waterman (with substitution matrices), ClustalW and TCoffee. Along those lines, what would the appropriate package to use for such classes? And where should the substitution matrices go? Thanks, Rahul _______________________________________________ biojava-dev mailing list biojava-dev@biojava.org http://biojava.org/mailman/listinfo/biojava-dev _______________________________________________ biojava-dev mailing list biojava-dev@biojava.org http://biojava.org/mailman/listinfo/biojava-dev From rahul at genebrew.com Sun Oct 3 22:05:05 2004 From: rahul at genebrew.com (Rahul Karnik) Date: Sun Oct 3 22:03:26 2004 Subject: [Biojava-dev] Alignment algorithms In-Reply-To: References: Message-ID: <4160AFD1.8090800@genebrew.com> mark.schreiber@group.novartis.com wrote: > Nope, looks like its gone to the big Hard Drive in the Sky. > > I could recode it if there is interest. I should have something ready in a couple of weeks. It's a good way to get used to BioJava. Thanks, Rahul From mark.schreiber at group.novartis.com Sun Oct 3 22:10:02 2004 From: mark.schreiber at group.novartis.com (mark.schreiber@group.novartis.com) Date: Sun Oct 3 22:09:30 2004 Subject: [Biojava-dev] Alignment algorithms Message-ID: As a word of advice, you will find it much easier to define some interfaces at the start such as SubstitutionTable, DPMatrix, DPAlgorithm. If you do this you can swap any substitution scoring system like Pam450 Blosum62 etc into any DPAlgorithm (NW or SW) while using any implementation of a DPMatrix (eg a basic one or a memory optimized sparse matrix). I could hopefully commit some basic Interfaces soon which could be developed to. - Mark Rahul Karnik 10/04/2004 10:05 AM To: Mark Schreiber/GP/Novartis@PH cc: biojava-dev@biojava.org, biojava-dev-bounces@portal.open-bio.org Subject: Re: [Biojava-dev] Alignment algorithms mark.schreiber@group.novartis.com wrote: > Nope, looks like its gone to the big Hard Drive in the Sky. > > I could recode it if there is interest. I should have something ready in a couple of weeks. It's a good way to get used to BioJava. 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There was an updated version of the schema posted to the BioJava mailing list a month or so ago, but I haven't looked at it in detail. Cheers, Len. > > (I'm also adding this to the other RDBMS's versions and will commit > when I tested them.) > > -hilmar > > On Tuesday, October 21, 2003, at 07:58 PM, Len Trigg wrote: > > > Hilmar Lapp wrote: > > > Sounds reasonable to me. Also, would be consistent with the other 2 > > > supported platforms. > > > > This reminds me, I ported the BioSQL schema to support HSQLDB, and > > added the neccessary support to BioJava's BioSQL binding. We use > > HSQLDB in our BioSQL unit tests, and I have seen references to other > > people making use of it. I have attached the appropriate schema files, > > if you wish include them as part of the BioSQL project (in which case > > BioSQL CVS can become the canonical location). > > > > > > Cheers, > > Len. > > > > > -- > ------------------------------------------------------------- > Hilmar Lapp email: lapp at gnf.org > GNF, San Diego, Ca. 92121 phone: +1-858-812-1757 > ------------------------------------------------------------- > > From su at seznam.cz Tue Oct 5 19:39:56 2004 From: su at seznam.cz (mogens) Date: Tue Oct 5 19:43:31 2004 Subject: [Biojava-dev] =?windows-1251?b?ze7i4P8g6u7r6+Xq9uj/?= Message-ID: <200410052343.i95NhPKr020602@portal.open-bio.org> ????? ????????? ??????????? ????? ?? ????? www.elitpresent.ru From sabrinamolina_gb at kt.co.kr Tue Oct 5 20:07:06 2004 From: sabrinamolina_gb at kt.co.kr (Sabrina Molina) Date: Tue Oct 5 20:06:11 2004 Subject: [Biojava-dev] =?iso-8859-1?q?Buy_cheap_V=ECagra_through_us=2E?= Message-ID: Hi, We have a new offer for you. 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Is anyone else having these problems? - Mark Mark Schreiber Principal Scientist (Bioinformatics) Novartis Institute for Tropical Diseases (NITD) 10 Biopolis Road #05-01 Chromos Singapore 138670 www.nitd.novartis.com phone +65 6722 2973 fax +65 6722 2910 From rahul at genebrew.com Wed Oct 6 01:29:45 2004 From: rahul at genebrew.com (Rahul Karnik) Date: Wed Oct 6 01:27:25 2004 Subject: [Biojava-dev] Problem downloading nightly build In-Reply-To: References: Message-ID: <1097040585.5557.3.camel@porsche.genebrew.com> On Wed, 2004-10-06 at 13:21 +0800, mark.schreiber@group.novartis.com wrote: > Hello - > > I don't seem to be able to download files from the nightly build. I have > tried with both IE and Konqueror. Is anyone else having these problems? Try: http://calette.derkholm.net/autobuild/ The link in the emails is wrong. Thanks, Rahul From mark.schreiber at group.novartis.com Wed Oct 6 01:37:40 2004 From: mark.schreiber at group.novartis.com (mark.schreiber@group.novartis.com) Date: Wed Oct 6 01:37:04 2004 Subject: [Biojava-dev] Problem downloading nightly build Message-ID: I'm getting to that site but the download still doesn't work?? Eventually it times out with a SERVER_RESPONSE_RESET message. Rahul Karnik 10/06/2004 01:29 PM To: Mark Schreiber/GP/Novartis@PH cc: biojava-dev@open-bio.org, td2@sanger.ac.uk Subject: Re: [Biojava-dev] Problem downloading nightly build On Wed, 2004-10-06 at 13:21 +0800, mark.schreiber@group.novartis.com wrote: > Hello - > > I don't seem to be able to download files from the nightly build. I have > tried with both IE and Konqueror. Is anyone else having these problems? Try: http://calette.derkholm.net/autobuild/ The link in the emails is wrong. Thanks, Rahul From rahul at genebrew.com Wed Oct 6 01:45:26 2004 From: rahul at genebrew.com (Rahul Karnik) Date: Wed Oct 6 01:43:10 2004 Subject: [Biojava-dev] Problem downloading nightly build In-Reply-To: References: Message-ID: <1097041526.5557.8.camel@porsche.genebrew.com> On Wed, 2004-10-06 at 13:37 +0800, mark.schreiber@group.novartis.com wrote: > I'm getting to that site but the download still doesn't work?? Eventually > it times out with a SERVER_RESPONSE_RESET message. Hmm, I just downloaded it successfully at about 5 KB/s. Server is quite slow for sure. Mirrored at http://www.genebrew.com/biojava-20041006.jar. Thanks, Rahul From rahul at genebrew.com Wed Oct 6 02:08:28 2004 From: rahul at genebrew.com (Rahul Karnik) Date: Wed Oct 6 02:06:15 2004 Subject: [Biojava-dev] [TRIVIAL PATCH] fix package name in demos/ssbind Message-ID: <1097042908.5557.14.camel@porsche.genebrew.com> Index: demos/ssbind/CountHits.java =================================================================== RCS file: /home/repository/biojava/biojava-live/demos/ssbind/CountHits.java,v retrieving revision 1.2 diff -u -r1.2 CountHits.java --- demos/ssbind/CountHits.java 25 Oct 2002 12:15:27 -0000 1.2 +++ demos/ssbind/CountHits.java 6 Oct 2004 05:34:12 -0000 @@ -1,4 +1,4 @@ -package ssearch; +package ssbind; import org.biojava.bio.search.*; Index: demos/ssbind/CountSubHits.java =================================================================== RCS file: /home/repository/biojava/biojava-live/demos/ssbind/CountSubHits.java,v retrieving revision 1.2 diff -u -r1.2 CountSubHits.java --- demos/ssbind/CountSubHits.java 25 Oct 2002 12:15:27 -0000 1.2 +++ demos/ssbind/CountSubHits.java 6 Oct 2004 05:34:12 -0000 @@ -1,4 +1,4 @@ -package ssearch; +package ssbind; import org.biojava.bio.search.*; From td2 at sanger.ac.uk Wed Oct 6 06:56:42 2004 From: td2 at sanger.ac.uk (Thomas Down) Date: Wed Oct 6 06:56:02 2004 Subject: [Biojava-dev] [TRIVIAL PATCH] fix package name in demos/ssbind In-Reply-To: <1097042908.5557.14.camel@porsche.genebrew.com> References: <1097042908.5557.14.camel@porsche.genebrew.com> Message-ID: <68111071-1786-11D9-AA1C-000A95C8B056@sanger.ac.uk> On 6 Oct 2004, at 07:08, Rahul Karnik wrote: > Index: demos/ssbind/CountHits.java > Index: demos/ssbind/CountSubHits.java Applied, thanks. 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I have writen during my graduation project Java classes with the most used algorithms in microarray data analysis, that are background correction, many normalization methods, and statistical analysis to detect differentially expressed genes. I'm finishing the manuscript that will be published as an application note in the Bioinformatics Journal. I would like to know if is interesting for the project to put my classes in BioJava. I think that it would increase the diversity of classes of BioJava, because my classes can serve as basis for softwares that deal with microarray data analysis and data manipulation. I wait for answer. Tiago _______________________________________________________ Yahoo! Acesso Gr?tis - Internet r?pida e gr?tis. Instale o discador agora! http://br.acesso.yahoo.com/ From mark.schreiber at group.novartis.com Thu Oct 7 21:46:23 2004 From: mark.schreiber at group.novartis.com (mark.schreiber@group.novartis.com) Date: Thu Oct 7 21:45:45 2004 Subject: [Biojava-dev] Microarray Features Message-ID: Hello - I think it would be great to have some of these classes. You could post them to the list as a Tar or you could get a cvs account to commit them and maintain them. Thomas, who can set up CVS accounts these days? - Mark Tiago Lopes Sent by: biojava-dev-bounces@portal.open-bio.org 10/07/2004 10:41 PM To: biojava-dev@biojava.org cc: (bcc: Mark Schreiber/GP/Novartis) Subject: [Biojava-dev] Microarray Features Hello, My name is Tiago Lopes, I'm from Brazil and I'm starting my Msc. in bioinformatics dealing with datamining, microarray and data visualization. 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Huen) Date: Fri Oct 8 14:28:53 2004 Subject: [Biojava-dev] Proposal for minor extension of BlastLikeDataSetCollection DTD Message-ID: The current DTD does not permit the passing of a query description line even though it permits a hit description line to be passed. I propose to add:- and modify the header to:- Are there any objections? Regards, David Huen From rahul at genebrew.com Fri Oct 8 22:46:24 2004 From: rahul at genebrew.com (Rahul Karnik) Date: Fri Oct 8 22:43:18 2004 Subject: [Biojava-dev] Biojava-dev bounces Message-ID: <41675100.9000702@genebrew.com> I sent some patches (5 new files) to biojava-dev two days ago and it is stuck in moderator limbo (biojava-dev-bounces) due to "suspicious headers". Any chance someone could unblock it so I could have some review of these changes? Also, tips on how to avoid the bounce in the future would be much appreciated. Thanks, Rahul From david.huen at ntlworld.com Sat Oct 9 04:45:24 2004 From: david.huen at ntlworld.com (David Huen) Date: Sat Oct 9 04:44:42 2004 Subject: [Biojava-dev] Biojava-dev bounces In-Reply-To: <41675100.9000702@genebrew.com> References: <41675100.9000702@genebrew.com> Message-ID: <200410090945.24906.david.huen@ntlworld.com> On Saturday 09 Oct 2004 03:46, Rahul Karnik wrote: > I sent some patches (5 new files) to biojava-dev two days ago and it is > stuck in moderator limbo (biojava-dev-bounces) due to "suspicious > headers". Any chance someone could unblock it so I could have some > review of these changes? Also, tips on how to avoid the bounce in the > future would be much appreciated. > Hi, This behaviour is rather hard to avoid on this list - I think it rejects enclosures and it has certainly done this to me too. OTOH, if you paste the text directly into the message, it usually gets through. I would unblock the email for you but i don't have moderator access. 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Stewart) Date: Mon Oct 11 11:48:32 2004 Subject: [Biojava-dev] OAT practice tests for students Message-ID: <035c01c4afa9$df670120$6700a8c0@mm7> I recommend adding a link: http://www.testprepreview.com/oat_practice.htm to your website. It has online OAT practice tests for no charge. From mark.schreiber at group.novartis.com Mon Oct 11 15:22:58 2004 From: mark.schreiber at group.novartis.com (mark.schreiber@group.novartis.com) Date: Mon Oct 11 15:24:47 2004 Subject: [Biojava-dev] Biojava-dev bounces Message-ID: Also, make sure you don't send HTML or RTF mail as these get blocked too. Part of the anti spam approach I think. - Mark David Huen Sent by: biojava-dev-bounces@portal.open-bio.org 10/09/2004 04:45 PM Please respond to smh1008 To: biojava-dev@biojava.org cc: (bcc: Mark Schreiber/GP/Novartis) Subject: Re: [Biojava-dev] Biojava-dev bounces On Saturday 09 Oct 2004 03:46, Rahul Karnik wrote: > I sent some patches (5 new files) to biojava-dev two days ago and it is > stuck in moderator limbo (biojava-dev-bounces) due to "suspicious > headers". Any chance someone could unblock it so I could have some > review of these changes? Also, tips on how to avoid the bounce in the > future would be much appreciated. > Hi, This behaviour is rather hard to avoid on this list - I think it rejects enclosures and it has certainly done this to me too. OTOH, if you paste the text directly into the message, it usually gets through. I would unblock the email for you but i don't have moderator access. 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Is this a bug or a feature? --Kevin Fowler void initDb(String biodatabase, boolean create) ... PreparedStatement getID = conn.prepareStatement("select * from biodatabase where name = ?"); getID.setString(1, biodatabase); ResultSet rs = getID.executeQuery(); if (rs.next()) { dbid = rs.getInt(1); name = rs.getString(2); rs.close(); getID.close(); conn.close(); return; } else { rs.close(); getID.close(); } if (create) { PreparedStatement createdb = conn.prepareStatement("insert into biodatabase (name) values ( ? )"); createdb.setString(1, biodatabase); createdb.executeUpdate(); conn.commit(); createdb.close(); dbid = getDBHelper().getInsertID(conn, "biodatabase", "biodatabase_id"); } else { ... -------------- next part -------------- A non-text attachment was scrubbed... Name: not available Type: text/enriched Size: 2048 bytes Desc: not available Url : http://portal.open-bio.org/pipermail/biojava-dev/attachments/20041003/45ea0644/attachment-0001.bin From arv_ind_ at hotmail.com Mon Oct 11 19:29:25 2004 From: arv_ind_ at hotmail.com (Arvind) Date: Thu Oct 14 09:14:29 2004 Subject: [Biojava-dev] Biojava SearchProfile.java Problem Message-ID: Hi, I am a newbie to Biojava. I obtained Biojava 1.4pre1 and compiled the source and the demos. I seem to be having some problems with the demo - especially SearchProfile.java. It seems to throw this exception: .. .. .. Forward: -918.1011438378875 Backward: -918.1011438378877 Training whole profile Cycle 1 completed Score: -2754.2394913554967 Cycle 2 completed Score: NaN Cycle 3 completed Score: NaN Cycle 4 completed Score: NaN Cycle 5 completed Score: NaN Alignining sequences to the model org.biojava.bio.seq.impl.SimpleSequence@1b3967 name: 3 java.lang.NullPointerException at org.biojava.bio.dp.onehead.SingleDP.viterbi(Sing at org.biojava.bio.dp.onehead.SingleDP.viterbi(Sing at SearchProfile2.main(SearchProfile2.java:62) Can you please help me out? I need it very badly to work. Thanks, Arvind From rahul at genebrew.com Thu Oct 7 00:44:34 2004 From: rahul at genebrew.com (Rahul Karnik) Date: Thu Oct 14 09:14:31 2004 Subject: [Biojava-dev] ScoringMatrix interface/implementations Message-ID: <1097124274.11694.14.camel@porsche.genebrew.com> As a first step in the building of a framework for sequence alignment, I have attached: - a ScoringMatrix interface - two simple implementations - a matrix reader - a junit test case and a test file Please let me know if and how I should integrate this ScoringMatrix design with the existing WeightMatrix used with the HMM code. Of course, any other comments and suggestions are welcome too. Thanks, Rahul -------------- next part -------------- A non-text attachment was scrubbed... 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Name: ScoringMatrixReaderTest.java Type: text/x-java Size: 2840 bytes Desc: not available Url : http://portal.open-bio.org/pipermail/biojava-dev/attachments/20041007/5b72fca2/ScoringMatrixReaderTest.bin -------------- next part -------------- # Matrix made by matblas from blosum50.iij # BLOSUM Clustered Scoring Matrix in 1/3 Bit Units # Blocks Database = /data/blocks_5.0/blocks.dat # Cluster Percentage: >= 50 # Entropy = 0.4808, Expected = -0.3573 A R N D C Q E G H I L K M F P S T W Y V B Z X A 5 -2 -1 -2 -1 -1 -1 0 -2 -1 -2 -1 -1 -3 -1 1 0 -3 -2 0 -2 -1 -1 R -2 7 -1 -2 -4 1 0 -3 0 -4 -3 3 -2 -3 -3 -1 -1 -3 -1 -3 -1 0 -1 N -1 -1 7 2 -2 0 0 0 1 -3 -4 0 -2 -4 -2 1 0 -4 -2 -3 4 0 -1 D -2 -2 2 8 -4 0 2 -1 -1 -4 -4 -1 -4 -5 -1 0 -1 -5 -3 -4 5 1 -1 C -1 -4 -2 -4 13 -3 -3 -3 -3 -2 -2 -3 -2 -2 -4 -1 -1 -5 -3 -1 -3 -3 -2 Q -1 1 0 0 -3 7 2 -2 1 -3 -2 2 0 -4 -1 0 -1 -1 -1 -3 0 4 -1 E -1 0 0 2 -3 2 6 -3 0 -4 -3 1 -2 -3 -1 -1 -1 -3 -2 -3 1 5 -1 G 0 -3 0 -1 -3 -2 -3 8 -2 -4 -4 -2 -3 -4 -2 0 -2 -3 -3 -4 -1 -2 -2 H -2 0 1 -1 -3 1 0 -2 10 -4 -3 0 -1 -1 -2 -1 -2 -3 2 -4 0 0 -1 I -1 -4 -3 -4 -2 -3 -4 -4 -4 5 2 -3 2 0 -3 -3 -1 -3 -1 4 -4 -3 -1 L -2 -3 -4 -4 -2 -2 -3 -4 -3 2 5 -3 3 1 -4 -3 -1 -2 -1 1 -4 -3 -1 K -1 3 0 -1 -3 2 1 -2 0 -3 -3 6 -2 -4 -1 0 -1 -3 -2 -3 0 1 -1 M -1 -2 -2 -4 -2 0 -2 -3 -1 2 3 -2 7 0 -3 -2 -1 -1 0 1 -3 -1 -1 F -3 -3 -4 -5 -2 -4 -3 -4 -1 0 1 -4 0 8 -4 -3 -2 1 4 -1 -4 -4 -2 P -1 -3 -2 -1 -4 -1 -1 -2 -2 -3 -4 -1 -3 -4 10 -1 -1 -4 -3 -3 -2 -1 -2 S 1 -1 1 0 -1 0 -1 0 -1 -3 -3 0 -2 -3 -1 5 2 -4 -2 -2 0 0 -1 T 0 -1 0 -1 -1 -1 -1 -2 -2 -1 -1 -1 -1 -2 -1 2 5 -3 -2 0 0 -1 0 W -3 -3 -4 -5 -5 -1 -3 -3 -3 -3 -2 -3 -1 1 -4 -4 -3 15 2 -3 -5 -2 -3 Y -2 -1 -2 -3 -3 -1 -2 -3 2 -1 -1 -2 0 4 -3 -2 -2 2 8 -1 -3 -2 -1 V 0 -3 -3 -4 -1 -3 -3 -4 -4 4 1 -3 1 -1 -3 -2 0 -3 -1 5 -4 -3 -1 B -2 -1 4 5 -3 0 1 -1 0 -4 -4 0 -3 -4 -2 0 0 -5 -3 -4 5 2 -1 Z -1 0 0 1 -3 4 5 -2 0 -3 -3 1 -1 -4 -1 0 -1 -2 -2 -3 2 5 -1 X -1 -1 -1 -1 -2 -1 -1 -2 -1 -1 -1 -1 -1 -2 -2 -1 0 -3 -1 -1 -1 -1 -1 From noreply at bestlabdeals.com Thu Oct 14 12:44:58 2004 From: noreply at bestlabdeals.com (Best Lab Deals) Date: Thu Oct 14 09:57:03 2004 Subject: [Biojava-dev] buying lab equipment can be fun Message-ID: <200410141644.i9EGiwgQ010642@earth.planetharvest.com> Best Lab Deals is the one source for researchers, industrial professionals, scientists, physicians, educators and hobbyists to find more than 40,000 products at prices up to 70% below retail. Precision calibration - repair service Best Lab Deals 919-661-8030 Subscribe to our special offers list and also receive our free online newsletter, with problem-solving ideas, trends and other critical information. This message is to verify that you wish to have your email address added to our newsletter distribution list. You MUST click here to have your email address added to our list. http://bestlabdeals.com/lists/confirm.php?uid=330673608375dc7e1282f990daa59cdb This is to ensure that someone does not add your address to our list without your prior knowledge or consent. Unless you respond to this email, your address is not added to our mailing list! Thanks, Customer Service From simon.foote at nrc-cnrc.gc.ca Thu Oct 14 10:21:46 2004 From: simon.foote at nrc-cnrc.gc.ca (Simon Foote) Date: Thu Oct 14 10:21:05 2004 Subject: [Biojava-dev] BioSQLSequenceDB Create Behavior In-Reply-To: <579B4AC4-15CD-11D9-89D9-000D93C5A5CA@sdsc.edu> References: <579B4AC4-15CD-11D9-89D9-000D93C5A5CA@sdsc.edu> Message-ID: <416E8B7A.6080008@nrc-cnrc.gc.ca> Hi Kevin, I think the thought behind that is, in order to create a new biodatabase you have to provide a name, so it would be redundant. Unless it is required lower down in the code somewhere, although I haven't seen a case of this yet. Also of note, one can't currently set the authority or version for a biodatabase during a create or retrieve them for an existing biodatabase. I do have the retrieve ability in my local copy, but haven't committed it in yet. Simon -- Bioinformatics Programmer Pathogen Genomics Institute for Biological Sciences National Research Council of Canada [T] 613-990-0561 [F] 613-952-9092 simon.foote@nrc-cnrc.gc.ca Kevin Fowler wrote: > Hi, > > > I notice that org.biojava.bio.seq.db.biosql.BioSQLSequenceDB doesn't > set the biodatabase name on create. > > for example: > > > db = new BioSQLSequenceDB(myDataSource,"MyName",true); > > assert(db.getName()==null); // true if the DB was created, > false if it already existed. > > > > Is this a bug or a feature? > > > --Kevin Fowler > > > > > * **void* initDb(String biodatabase,* boolean* create) > > ... > > PreparedStatement getID = conn.prepareStatement(*"select * from > biodatabase where name = ?"*); > > getID.setString(1, biodatabase); > > ResultSet rs = getID.executeQuery(); > > * if* (rs.next()) { > > dbid = rs.getInt(1); > > name = rs.getString(2); > > rs.close(); > > getID.close(); > > conn.close(); > > * return*; > > }* else* { > > rs.close(); > > getID.close(); > > } > > > * if* (create) { > > PreparedStatement createdb = conn.prepareStatement(*"insert into > biodatabase (name) values ( ? )"*); > > createdb.setString(1, biodatabase); > > createdb.executeUpdate(); > > conn.commit(); > > createdb.close(); > > > dbid = getDBHelper().getInsertID(conn,* "biodatabase"*,* > "biodatabase_id"*); > > }* else* { > > ... > >------------------------------------------------------------------------ > >_______________________________________________ >biojava-dev mailing list >biojava-dev@biojava.org >http://biojava.org/mailman/listinfo/biojava-dev > > -- Bioinformatics Programmer Pathogen Genomics Institute for Biological Sciences National Research Council of Canada [T] 613-990-0561 [F] 613-952-9092 simon.foote@nrc-cnrc.gc.ca From mark.schreiber at group.novartis.com Thu Oct 14 11:45:42 2004 From: mark.schreiber at group.novartis.com (mark.schreiber@group.novartis.com) Date: Thu Oct 14 11:44:48 2004 Subject: [Biojava-dev] ScoringMatrix interface/implementations Message-ID: Hi Rahul - I like this approach. The only minor problem is what to do with ambiguities that are not found in the matrix. Currently you through an exception which is fine although you might also want another implementation that more gracefully averages the match values of all the possible sub-symbols of the ambiguity. Looking forward to seeing the rest. Mark Rahul Karnik Sent by: biojava-dev-bounces@portal.open-bio.org 10/07/2004 12:44 PM To: BioJava Dev cc: (bcc: Mark Schreiber/GP/Novartis) Subject: [Biojava-dev] ScoringMatrix interface/implementations As a first step in the building of a framework for sequence alignment, I have attached: - a ScoringMatrix interface - two simple implementations - a matrix reader - a junit test case and a test file Please let me know if and how I should integrate this ScoringMatrix design with the existing WeightMatrix used with the HMM code. Of course, any other comments and suggestions are welcome too. Thanks, Rahul _______________________________________________ biojava-dev mailing list biojava-dev@biojava.org http://biojava.org/mailman/listinfo/biojava-dev [ Attachment ''SCORINGMATRIX.JAVA'' removed by Mark Schreiber ] [ Attachment ''SIMPLESCORINGMATRIX.JAVA'' removed by Mark Schreiber ] [ Attachment ''SYMMETRICSCORINGMATRIX.JAVA'' removed by Mark Schreiber ] [ Attachment ''SCORINGMATRIXREADER.JAVA'' removed by Mark Schreiber ] [ Attachment ''SCORINGMATRIXREADERTEST.JAVA'' removed by Mark Schreiber ] [ Attachment ''BLOSUM50.MATRIX'' removed by Mark Schreiber ] From bearvmindand at usa.com Thu Oct 14 08:04:53 2004 From: bearvmindand at usa.com (Matthew Glave) Date: Thu Oct 14 15:09:22 2004 Subject: [Biojava-dev] Bloody Virginz Message-ID: <9bbeaeab310$bf327bc3$e26a2ff5@usa.com> Bloody Virginz This is the most awesome site you will ever come across... the one place on the internet where you will find actual defloration of rea1 v1rg1nz. We bring you beautiful virgins who REALLY loose it right before your eyes to TWO hard, hung guys. Every Saturday, you're invited to Edik and Vadim's private se>< Party. Check out: http://bird.airs.fgedasi.com/blodyrgin/index.html You can remve yur e-mal. http://hurry.splashing.fgedasi.com/blodyrgin/sdfdegret/index.html She didn't object to Miena. That's why we are working so hard right now to keep the water high. Scalps, what a joke, now every trail guide would want to be decorated with the "scalps" displayed on their horse to show their "honor within the Tribe". gro.avajoib Pushing against the walls with her webbed toes, she sought to swim faster but only stirred up mud, twigs and debris that clouded the passageway. .sbk.ved.tir.avajoib He was distracted by a loud "quack-wack-wack" and "rab-rab-rab". "Why not?" From rahul at genebrew.com Thu Oct 14 18:58:33 2004 From: rahul at genebrew.com (Rahul Karnik) Date: Thu Oct 14 18:53:44 2004 Subject: [Biojava-dev] ScoringMatrix interface/implementations In-Reply-To: References: Message-ID: <416F0499.6060802@genebrew.com> mark.schreiber@group.novartis.com wrote: > I like this approach. The only minor problem is what to do with > ambiguities that are not found in the matrix. Currently you through an > exception which is fine although you might also want another > implementation that more gracefully averages the match values of all the > possible sub-symbols of the ambiguity. Thanks for the feedback. I am going to put off the averaging for ambiguities for now, mainly because ambiguous bases can also be added to the ScoringMatrix. As you say, it could be yet another implementation down the road. 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Could somebody who has a functional HSQLDB server test the DDL script to weed out any possible typos and syntax errors? -hilmar On Wednesday, October 6, 2004, at 11:30 AM, Len Trigg wrote: > At Wed, 6 Oct 2004 09:22:42 -0700, > Hilmar Lapp wrote: > > > > > > On Tuesday, October 5, 2004, at 02:10? PM, Len Trigg wrote: > > > > > There was an updated version of the schema posted to the BioJava > > > mailing list a month or so ago, but I haven't looked at it in > detail. > > > > > > > Could somebody point me to the respective email in the archives, or > at > > least provide either of subject or author? > > http://www.biojava.org/pipermail/biojava-dev/2004-August/001950.html > > I think the only additions were adding primary key statements. 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Click here: http://koolrx.com/meds/ Best regards, Donald Cunfingham No thanks: http://koolrx.com/rm.html From Russell.Smithies at agresearch.co.nz Mon Oct 18 21:54:04 2004 From: Russell.Smithies at agresearch.co.nz (Smithies, Russell) Date: Mon Oct 18 21:53:00 2004 Subject: [Biojava-dev] GFF3 writer? Message-ID: Is anyone working on a writer for GFF3? GMOD wants input in this format and I'm not sure if the current GFFWriter will do it. thanx, Russell Smithies Bioinformatics Software Developer AgResearch Invermay Private Bag 50034 Puddle Alley Mosgiel New Zealand Tel: +64 3 489 9085 Fax: +64 3 489 3739 ======================================================================= Attention: The information contained in this message and/or attachments from AgResearch Limited is intended only for the persons or entities to which it is addressed and may contain confidential and/or privileged material. Any review, retransmission, dissemination or other use of, or taking of any action in reliance upon, this information by persons or entities other than the intended recipients is prohibited by AgResearch Limited. If you have received this message in error, please notify the sender immediately. ======================================================================= From autobuilder at derkholm.net Tue Oct 19 00:11:11 2004 From: autobuilder at derkholm.net (autobuilder@derkholm.net) Date: Mon Oct 18 23:38:30 2004 Subject: [Biojava-dev] [biojava-builder] BioJava nightly build report Message-ID: <31156635.1098159071753.JavaMail.thomas@calette.derkholm.net> BioJava automatic build system, run 20041019 Binary build: OK Javadocs build: OK Core test suite: OK A snapshot release has been made at: http://www.derkholm.net/autobuild/ No changes were made in the last 24 hours. -- BioJava Autobuilder, maintained by Thomas Down If you notice any problems, contact autobuilder@derkholm.net From td2 at sanger.ac.uk Tue Oct 19 04:16:23 2004 From: td2 at sanger.ac.uk (Thomas Down) Date: Tue Oct 19 04:15:51 2004 Subject: [Biojava-dev] GFF3 writer? In-Reply-To: References: Message-ID: <2A0CB486-21A7-11D9-8FB2-000A95C8B056@sanger.ac.uk> On 19 Oct 2004, at 02:54, Smithies, Russell wrote: > > Is anyone working on a writer for GFF3? > GMOD wants input in this format and I'm not sure if the current > GFFWriter will do it. Just been taking a look at the GFF3 spec: http://song.sourceforge.net/gff3.shtml There's one change which definitely makes our current GFFWriter non-compliant. GFF2 specified tag-value attribute data with a space between the tag and value. GFF3 seems to use tag1=value1;tag2=value2 instead. It shouldn't be too hard to add a GFF3Writer to the existing bio.program.gff3 package -- basically just change this, plus the version header at the top :-) Thomas. 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Get it here: http://koolrx.com/sup/ Best regards, Jeremy Stones No thanks: http://koolrx.com/rm.html From taylorhardy_ya at renfe.es Tue Oct 19 08:39:34 2004 From: taylorhardy_ya at renfe.es (Taylor Hardy) Date: Tue Oct 19 08:41:50 2004 Subject: [Biojava-dev] Italian Crafted Rolex from $75 to $275 - Free Shipping Message-ID: <43a401c4b5d8$3070e7e4$8b44774e@aagaskets.com.au> Heya, Do you want a rolex watch? In our online store you can buy replicas of Rolex watches. They look and feel exactly like the real thing. - We have 20+ different brands in our selection - Free shipping if you order 5 or more - Save up to 40% compared to the cost of other replicas - Standard Features: - Screw-in crown - Unidirectional turning bezel where appropriate - All the appropriate rolex logos, on crown and dial - Heavy weight Visit us: http://www.toels.com/replica/rolex/ Best regards, Hilton Jones No thanks: http://toels.com/z.php From heuermh at acm.org Tue Oct 19 11:37:26 2004 From: heuermh at acm.org (Michael Heuer) Date: Tue Oct 19 11:33:52 2004 Subject: [Biojava-dev] [bjv2] org.bjv2.graph In-Reply-To: Message-ID: Hello Matthew, Just wanted to point you to the graph API I had been working on, at > https://dsh-lib.dev.java.net/source/browse/dsh-lib/graph/ > http://ccgb.umn.edu/~heuer/graph/apidocs/org/dishevelled/graph/Graph.html There are a few things in that design I still am not comfortable with (you may remember questions I had with generics some time back), but I do think that it is better to have an interface Node that holds a generic type N than to just hold generic Nodes as in your design. To me it makes more sense to traverse over Nodes with a visitor pattern than to call methods on Graph (Node.inEdges, Node.outEdges vs. Graph.getArcsFrom, getArcsTo). I also find the node and edge maps very useful for implementing traversal and search algorithms, as a convenient way of storing visited or color information. (e.g. Map Graph.nodeMap()) michael From cjacobs_qx at semperflex.cz Tue Oct 19 12:36:00 2004 From: cjacobs_qx at semperflex.cz (Clarence Jacobs) Date: Tue Oct 19 12:37:47 2004 Subject: [Biojava-dev] =?iso-8859-1?q?New!_V=ECagra_soft_tabs=2E?= Message-ID: Hello! We would like to offer V_I_A_G_R_A soft tabs, These pills are just like regular V?agra but they are specially formulated to be soft and dissolvable under the tongue. The pill is absorbed at the mouth and enters the bloodstream directly instead of going through the stomach. This results in a faster more powerful effect which lasts as long as the normal. 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You can get it at: http://koolrx.com/st/?coupon No thanks: http://koolrx.com/rm.html From autobuilder at derkholm.net Wed Oct 20 00:11:05 2004 From: autobuilder at derkholm.net (autobuilder@derkholm.net) Date: Tue Oct 19 23:38:11 2004 Subject: [Biojava-dev] [biojava-builder] BioJava nightly build report Message-ID: <31156635.1098245465966.JavaMail.thomas@calette.derkholm.net> BioJava automatic build system, run 20041020 Binary build: OK Javadocs build: OK Core test suite: OK A snapshot release has been made at: http://www.derkholm.net/autobuild/ The following files were modified in the last 24 hours: * biojava-live/src/org/biojava/bio/search/BioMatcher.java * biojava-live/src/org/biojava/bio/search/BioPattern.java * biojava-live/src/org/biojava/bio/search/BlastLikeSearchFilter.java * biojava-live/src/org/biojava/bio/search/FilterTest.java * biojava-live/src/org/biojava/bio/search/FilteringContentHandler.java * biojava-live/src/org/biojava/bio/search/MaxMismatchMatcher.java * biojava-live/src/org/biojava/bio/search/MaxMismatchPattern.java * biojava-live/src/org/biojava/bio/search/SeqContentMatcher.java * biojava-live/src/org/biojava/bio/search/SeqContentPattern.java * biojava-live/src/org/biojava/utils/TriState.java * biojava-live/tests/files/biosqldb-hsqldb.sql * biojava-live/tests/files/drop-biosqldb-hsqldb.sql A patch file reflecting these changes is available from http://www.derkholm.net/autobuild/patches/ -- BioJava Autobuilder, maintained by Thomas Down If you notice any problems, contact autobuilder@derkholm.net From hlapp at gnf.org Wed Oct 20 02:15:47 2004 From: hlapp at gnf.org (Hilmar Lapp) Date: Wed Oct 20 02:16:22 2004 Subject: [Biojava-dev] Re: HSQLDB support... In-Reply-To: Message-ID: <7B9AA597-225F-11D9-BEE4-000A959EB4C4@gnf.org> On Tuesday, October 19, 2004, at 08:18 PM, Len Trigg wrote: > I plugged the version from BioSQL CVS into the BioJava unit tests and > wiggled with them until they worked (other than the couple of known > problems with the BioJava BioSQL support). Thanks a lot for your help. I greatly appreciate it. > > biosqldb-hsqldb.sql is checked in with windows line endings. Fixed. > Other than that, the name field of the term_synonym table was > incorrect > (patch attached). Fixed. However, doesn't that mean that this column name needs to be changed in the PostgreSQL version as well? Or does Biojava revert to 'synonym' then? > > I also updated the drop-biosqldb-hsqldb.sql. Thanks, a applied this too. 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You can get it at: http://a1medz.com/soft/ No thanks: http://a1medz.com/rr.php From ephraim at ultrapostman.com Sun Oct 31 17:05:59 2004 From: ephraim at ultrapostman.com (=?Windows-1251?B?0OXq6+Ds7e7lIO/w5eTr7ubl7ejl?=) Date: Sun Oct 31 17:15:42 2004 Subject: [Biojava-dev] =?windows-1251?b?0OXq6+Ds4DogyOfk5evo/yDo5yDq7ubo?= =?windows-1251?b?IO/uIOjt5Oji6OTz4Ov87e7s8yDn4Org5/MhISEg0PP37eD/IPDg4e7y?= =?windows-1251?q?=E0!!!?= Message-ID: <131853603.20041031221059@> ??????? ??????? ?? ??????????????? ??????!!! ?????? ??????!!! ??????? ?? ????: ?????????????, ?????? 9,5 ? 6,5 ?? - 5 ?.?. ???????, ?????? 16 ? 12 ?? - 11 ?.?. ????? ??? ?????? ??????? ?5 - ?? 20 ?.?. ????? ????, ????? ??? ????? ??????? ?4 - ?? 30 ?.?. ??????? ? ??????????? ??????????? ????????? ( ??????, ???????, ????, ?????, ???????) ???????????? ( ??????, ???????, ????? ?????) ???????? ???????????? ???????? ?? ????? ???????? ?? ????: ?????, ???????, ????????, ?????, ???????????, ?????????, ????????? ???? ? ?????? ? ???????. ??????? ????? ????????? ? ????? ???????????? ??????????. ????? ?????, ???? ???????????????? ???? ????????? ????????? ??????????? ? ??????: ??????????? ?) ???????? (????????, ?????, ??????, ?????, ???????...). ??????????? ?????? 6?6 M&R "Chameleon" (???, ??????????????????: 3+0, 960 ??????? ??????? ? ?????). ?) ??????????, ??????, ???????, ??????, ??????, ???? (?????? ???????? ? ???, ????????, ????? - ??????, ??????? ?/?...) ?????????????? ?????? Winnon, ??????? ????????? 30?30 ??. ???????????. Winnon - 121. ????????? ?? ?????, ?????????, ???????, ??????, ??????????, ????, ???????, ????. ????, ????????????????. ??????? ????? ???????????? ????????- ?????????? ????????? ?? ?????????. ?????????? ?????. ?????????? ??????, ???????, ?????? ???????????. ???????????? ?????????? ????????,?????????????? ???????, ??????????,???????? ??????? ????????? ???????????. ??????? ????? ?????? ?? ????????: ? ??? ????????? ??????? ??? ??????????? ? ?????????? ? ?????????! (095) 7-888-769 (095) 101-3527 (????????.) 8 (926) 523 - 42-41 (?????????????) ?? ????? ??????? ????????? ???????? ???????????????. ??????? ?? ?????????? ?????? ? ?????? ????? ????? ? ????? "??" - ????????? ???????????, ? ????? "????" - ???????: (???????? ??????????? ????, ????????, ??????, ?????? ? ??.) ???? ?? ?? ??????? ???????? ????????? ??????????? ?? ??????????? ?????, ?? ?????? ??????? ???? ????? ?? ????? ???? ??????, ??????? ??? ?????? ? ????? ??????? ???????? ? ???? ??????, ?? ??????: nevajno2000@yahoo.com ?? ?????? ???? ???????, ??? ?? ?? ????? ???? ?????? ??? ???????? ????? ?? ????? ???? ??????. ?????? ???? ???????????? 20 ????? ??????? ??????. From len at reeltwo.com Tue Oct 19 23:17:56 2004 From: len at reeltwo.com (Len Trigg) Date: Sun Nov 21 16:10:37 2004 Subject: [Biojava-dev] Re: HSQLDB support... In-Reply-To: <389B9928-2094-11D9-AF76-000A959EB4C4@gnf.org> References: <389B9928-2094-11D9-AF76-000A959EB4C4@gnf.org> Message-ID: Hilmar Lapp wrote: > I added the primary key constraints. Could somebody who has a > functional HSQLDB server test the DDL script to weed out any possible > typos and syntax errors? I plugged the version from BioSQL CVS into the BioJava unit tests and wiggled with them until they worked (other than the couple of known problems with the BioJava BioSQL support). biosqldb-hsqldb.sql is checked in with windows line endings. Other than that, the name field of the term_synonym table was incorrect (patch attached). I also updated the drop-biosqldb-hsqldb.sql. Cheers, Len. -------------- next part -------------- A non-text attachment was scrubbed... Name: biosqldb-hsqldb.sql.patch Type: application/octet-stream Size: 645 bytes Desc: not available Url : http://portal.open-bio.org/pipermail/biojava-dev/attachments/20041020/bf56d9b0/biosqldb-hsqldb.sql.obj -------------- next part -------------- A non-text attachment was scrubbed... Name: drop-biosqldb-hsqldb.sql.patch Type: application/octet-stream Size: 5585 bytes Desc: not available Url : http://portal.open-bio.org/pipermail/biojava-dev/attachments/20041020/bf56d9b0/drop-biosqldb-hsqldb.sql.obj From ulimard at yahoo.com.br Wed Oct 20 16:55:30 2004 From: ulimard at yahoo.com.br (Ulisses Dias) Date: Sun Nov 21 16:10:44 2004 Subject: [Biojava-dev] Alignment Message-ID: <20041020205643.2432.qmail@web50506.mail.yahoo.com> Hi All, I'd like to align two sequences and i want to know if there is a predefined function in biojava or I must to create one. If somebody could help me, I would be glad too. Ulisses Dias --------------------------------- Yahoo! Acesso Gr?tis - Internet r?pida e gr?tis. Instale o discador agora! From ulimard at yahoo.com.br Wed Oct 20 17:08:35 2004 From: ulimard at yahoo.com.br (Ulisses Dias) Date: Sun Nov 21 16:10:47 2004 Subject: [Biojava-dev] Phred Message-ID: <20041020210948.95081.qmail@web50501.mail.yahoo.com> Hi, all. It's me again. I'm a newbie in bioJava, but I'm a expert in Java. I have other doubt, What are the facilities that I could use with the class Phred ... I'd like to get a file from the hard disk (phred format) and use it in my java aplication. It's possible??? Ulisses Dias __________________________________________________ Do You Yahoo!? Tired of spam? Yahoo! Mail has the best spam protection around http://mail.yahoo.com